Lifeboat Foundation: Safeguarding Humanity
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New York, NY (December 12, 2022) A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

The therapy, known as a bispecific antibody, binds to both T cells and multiple myeloma cells and directs the T cells—white blood cells that can be enlisted to fight off diseases—to kill multiple myeloma cells. The researchers described this strategy as “bringing your army right to the enemy.”

The success of the off-the-shelf immunotherapy, called talquetamab, was even seen in patients whose cancer was resistant to all approved multiple myeloma therapies. It uses a different target than other approved therapies: a receptor expressed on the surface of cancer cells known as GPRC5D.

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Summary: A new brain mapping study reveals a neural network in cuttlefish that involves chemosensory function and body pattern control which the cuttlefish utilize for foraging and camouflage.

Source: University of Queensland

New mapping of the cuttlefish brain could explain how, and why, the marine animal employs its distinct camouflage ability according to researchers from The University of Queensland (UQ).

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Source: Penn State

Understanding the neural interface within the brain is critical to understanding aging, learning, disease progression and more. Existing methods for studying neurons in animal brains to better understand human brains, however, all carry limitations, from being too invasive to not detecting enough information.

A newly developed, pop-up electrode device could gather more in-depth information about individual neurons and their interactions with each other while limiting the potential for brain tissue damage.

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Nine military officers who had worked decades ago at a nuclear missile base in Montana have been diagnosed with blood cancer and there are “indications” the disease may be linked to their service, according to military briefing slides obtained by The Associated Press. One of the officers has died.

All of the officers, known as missileers, were assigned as many as 25 years ago to Malmstrom Air Force Base, home to a vast field of 150 Minuteman III intercontinental ballistic missile silos. The nine officers were diagnosed with non-Hodgkin lymphoma, according to a January briefing by U.S. Space Force Lt. Col. Daniel Sebeck.

Missileers ride caged elevators deep underground into a small operations bunker encased in a thick wall of concrete and steel. They remain there sometimes for days, ready to turn the launch keys if ordered to by the president.

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By ten years.

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.

Associated with exceptional longevity, carriers of healthy mutant , like those living in blue zones of the planet, often live to 100 years or more and remain in . These individuals are also less prone to cardiovascular complications. Scientists believe the gene helps to keep their hearts young by protecting them against diseases linked to aging, such as .

In this new study, researchers demonstrate that one of these healthy mutant genes, previously proved particularly frequent in centenarians, can protect cells collected from patients with failure requiring cardiac transplantation.

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