WebMD’s Chief Medical Officer, John Whyte, MD, speaks with Alicja Rudnicka, Professor, Statistical Epidemiology, St. George’s University of London, about an artificial intelligence-enhanced retinal exam that could help predict your risk for cardiovascular disease.
PROVIDENCE, R.I. [Brown University] — When it comes to predicting disasters brought on by extreme events (think earthquakes, pandemics or “rogue waves” that could destroy coastal structures), computational modeling faces an almost insurmountable challenge: Statistically speaking, these events are so rare that there’s just not enough data on them to use predictive models to accurately forecast when they’ll happen next.
But a team of researchers from Brown University and Massachusetts Institute of Technology say it doesn’t have to be that way.
In a new study in Nature Computational Science, the scientists describe how they combined statistical algorithms — which need less data to make accurate, efficient predictions — with a powerful machine learning technique developed at Brown and trained it to predict scenarios, probabilities and sometimes even the timeline of rare events despite the lack of historical record on them.
BIRMINGHAM, United Kingdom — Servers around the world could soon face a massive data storage crunch, thanks to the “mind-blowing amount” of information people store digitally every day.
Researchers from Aston University say the global datasphere — the total amount of data worldwide — will increase by 300 percent within the next three years. Currently, all of this data sits in banks of servers stored in huge warehouses (data centers).
Unfortunately, the answer to creating more space in “the cloud” is not just to build more server warehouses. The Aston team says data centers already use up 1.5 percent of the world’s electricity every year. That makes endlessly building new facilities just for massive servers an unsustainable practice.
BERLIN — A biotechnologist in Germany is developing the world’s first artificial womb facility, and it lets you choose baby’s characteristics from a menu. EctoLife, able to grow 30,000 babies a year, is said to be based on over fifty years of groundbreaking scientific research.
The concept is the brainchild of Berlin-based Hashem Al-Ghaili. He says the facilities would allow infertile couples to conceive a baby and become the true biological parents of their own offspring.
A so-called ‘Elite Package’ would allow you to genetically engineer the embryo before implanting it into the artificial womb. Everything from eye and hair color to strength, height, and intelligence can be chosen, and inherited genetic diseases can be avoided.
The world’s best artists can take a handful of differently colored paints and create a museum-worthy canvas that looks like nothing else. They do so by drawing upon inspiration, knowledge of what’s been done in the past and design rules they learned after years in the studio.
Chemists work in a similar way when inventing new compounds. Researchers at the U.S. Department of Energy’s (DOE) Argonne National Laboratory, Northwestern University and The University of Chicago have developed a new method for discovering and making new crystalline materials with two or more elements.
“We expect that our work will prove extremely valuable to the chemistry, materials and condensed matter communities for synthesizing new and currently unpredictable materials with exotic properties,” said Mercouri Kanatzidis, a chemistry professor at Northwestern with a joint appointment at Argonne.
Many medical treatments have toxicities, sometimes called adverse events, which can complicate a patient’s treatment regimen. Treatment-related adverse events can range from mild symptoms, like transient fatigue or nausea, to severe and lethal occurrences, including cardiac toxicity.
Cardiac toxicity, which manifests as indications like acute myocardial infarction (MI), and angina pectoris (AP), can occur in cancer survivors, even several years following successful treatment. The onset of heart-related adverse events long after treatment is known as late cardiac toxicity, which can become a lethal complication of cancer therapies like radiation and chemotherapy.
The mechanism underlying late cardiac toxicity remains poorly understood. Further, limited interventions to prevent or minimize these symptoms exist. This creates an urgent need to study this relationship and develop therapeutics which can stop or prevent late cardiac toxicity in cancer survivors.
S cientifically, it’s called ectogenesis, a term coined by J.B.S. Haldane in 1924. A hugely influential science popularizer, Haldane did for his generation what Carl Sagan did later in the century. He got people thinking and talking about the implications of science and technology on our civilization, and did not shy away from inventing new words in order to do so. Describing ectogenesis as pregnancy occurring in an artificial environment, from fertilization to birth, Haldane predicted that by 2074 this would account for more than 70 percent of human births.
His prediction may yet be on target.
In discussing the idea in his work Daedalus –a reference to the inventor in Greek mythology who, through his inventions, strived to bring humans to the level of the gods–Haldane was diving into issues of his time, namely eugenics and the first widespread debates over contraception and population control.
A Kent team, led by Professors Ben Goult and Jen Hiscock, has created and patented a ground-breaking new shock-absorbing material that could revolutionise both the defence and planetary science sectors.
This novel protein-based family of materials, named TSAM (Talin Shock Absorbing Materials), represents the first known example of a SynBio (or synthetic biology) material capable of absorbing supersonic projectile impacts. This opens the door for the development of next-generation bullet-proof armour and projectile capture materials to enable the study of hypervelocity impacts in space and the upper atmosphere (astrophysics).
Professor Ben Goult explained: ‘Our work on the protein talin, which is the cells natural shock absorber, has shown that this molecule contains a series of binary switch domains which open under tension and refold again once tension drops. This response to force gives talin its molecular shock absorbing properties, protecting our cells from the effects of large force changes. When we polymerised talin into a TSAM, we found the shock absorbing properties of talin monomers imparted the material with incredible properties.’
It was once thought that inflammation and immune responses in the brain were limited; that is was a so-called immune privileged organ. But there is increasing evidence to the contrary. New research has shown that immune cells called mucosal-associated invariant T cells (MAITs) can serve critical roles in the brain that reduce the levels of damaging reactive oxygen species, which prevents neuroinflammation, and protects learning and memory. The findings have been reported in Nature Immunology.
In this study, researchers genetically engineered mice so MAITs would no longer be produced. These mice were compared to a normal group and mice and while cognitive function was the same in both groups to start with, difference appeared as the mice approached middle age. The MAIT-deficient mice had difficulty forming new memories.
Researchers from MIT want to use a massive, powerfull laser, shoot it into outer space in an attempt to attract aliens to Earth.
