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Altos Labs just redefined big in biotech. Where to start? The $3 billion in investor support? The C-suite staffed by storied leaders—Barron, Bishop, Klausner—identifiable by one name? Or the wildly ambitious plan to reverse disease for patients of any age? Altos is all that and more.

Early details of Altos leaked out last year when MIT Technology Review reported Jeff Bezos had invested to support development of technology that could “revitalize entire animal bodies, ultimately prolonging human life.” The official reveal fleshes out the vision and grounds the technology in the context of the nearer-term opportunities it presents to improve human health.

“It’s clear from work by Shinya Yamanaka, and many others since his initial discoveries, that cells have the ability to rejuvenate, resetting their epigenetic clocks and erasing damage from a myriad of stressors. These insights, combined with major advances in a number of transformative technologies, inspired Altos to reimagine medical treatments where reversing disease for patients of any age is possible,” Hal Barron, M.D., said in a statement.

Deep Learning AI Specialization: https://imp.i384100.net/GET-STARTED
A breakthrough artificial intelligence called SinFusion can now take any video as input and extrapolate a synthetic video as output, either moving forward or backward in time, using a diffusion model. Google AI has released a new robotics transformer (RT-1) that does over 700 tasks using a fleet of 13 different robot arms with 7 degrees of freedom and a 2 fingered gripper manipulator. Researchers from Korea have developed a quadruped robot that is able to walk on walls and ceilings using magnetic elastomers and electromagnets.

AI News Timestamps:
0:00 The Rise of AI Diffusion Models.
1:08 Custom AI Diffusion Model Options.
1:27 What Is SinFusion AI
2:35 How Sinfusion AI Works.
4:04 New Google AI Robot Tech.
6:28 New Robotics That Walk on Walls.

#technology #tech #ai

Summary: Study finds a link between poor hydration in adults and an increased risk of chronic health conditions and advanced biological aging.

Source: NIH

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine. .

This Video Explains Small nuclear RNA (snRNA) and SPLICEOSOME.
Reference: https://www.frontiersin.org/articles/10.3389/fcell.2020.00474/full.
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Water on the Moon has been a hot topic in the research world lately. Since its first unambiguous discovery back in 2008. Since then, findings of it have ramped up, with relatively high concentration levels being discovered, especially near the polar regions, particularly in areas constantly shrouded in shadow. Chang’e 5, China’s recent sample return mission, didn’t land in one of those permanently shadowed areas. Still, it did return soil samples that were at a much higher latitude than any that had been previously collected. Now, a new study shows that those soil samples contain water and that the Sun’s solar wind directly impacted that water.

The amount of water on the lunar surface varies widely both based on the time of the lunar day and the latitude it is located at. There is so much variability that the water content of the lunar soil can be 200 ppm higher or lower at different times of the day. With that much variability, it seems clear that the Sun plays a significant role in the hydrological cycle there is on the Moon.

Part of that role is controlling the type of hydrogen embedded into the lunar soil. Since the Moon has almost no atmosphere to speak of, the charged hydrogen particles that make up the solar wind can directly interact with the top regolith layer on the lunar surface. When they do so, they leave behind a distinct sign that they do – a large amount of hydrogen atoms with very little deuterium.

Viruses impact host cells and have indirect effects on ecosystem processes. Plankton such as ciliates can reduce the abundance of virions in water, but whether virus consumption translates into demographic consequences for the grazers is unknown. Here, we show that small protists not only can consume viruses they also can grow and divide given only viruses to eat. Moreover, the ciliate Halteria sp. foraging on chloroviruses displays dynamics and interaction parameters that are similar to other microbial trophic interactions. These results suggest that the effect of viruses on ecosystems extends beyond (and in contrast to) the viral shunt by redirecting energy up food chains.

Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy. The advancements could help provide future insight into neuroscience, pathology, and many other biological and medical fields.

In the paper “Magnify is a universal molecular anchoring strategy for ,” published Jan. 2 in the journal Nature Biotechnology, collaborators from Carnegie Mellon University, the University of Pittsburgh and Brown University describe new protocols for dubbed Magnify.

“Magnify can be a potent and accessible tool for the biotechnology community,” said Yongxin (Leon) Zhao, the Eberly Family Career Development Associate Professor of Biological Sciences.