Lifeboat Foundation

In nature, wood, shells, and other structural materials are lightweight, strong, and tough. Significantly, these materials are made at the ambient temperature in the local environment – not at the high temperatures at which human-made structural materials are generally processed. Similar materials are difficult to make synthetically. In a review article in Nature Materials, a team of scientists assessed the common design motifs of a range of natural structural materials and determined what it would take to design and fabricate structures that mimic nature. They considered the remaining challenges to include the need for comprehensive characterization of strength and toughness to identify underlying multiscale mechanisms.

This comprehensive assessment provides new inspiration and understanding of design principles that may lead to more efficient synthetic approaches for advanced, lightweight structural materials for transportation, buildings, batteries, and energy conversion.

In the natural world, many of the structural materials (wood, shells, bones, etc.) are hybrid materials made up of simple constituents that are assembled at ambient temperatures and often have remarkable properties. Even though the constituent materials generally have poor intrinsic properties, the superior extrinsic properties of the hybrid materials are the result of the arrangement of hard and soft phases in complex hierarchical architectures, with dimensions spanning from the nanoscale to the macroscale. The resulting materials are lightweight and usually show interesting combinations of strength and toughness, even though these two key structural properties tend to be mutually exclusive. It is relatively easy to make materials that are strong or tough, but difficult to make materials that are both.

Summary: Understanding how changes in the brain relate to changes in well-being is key to developing new targets for the treatment of mental health disorders.

Source: University of Oxford.

Associate Professor Miriam Klein-Flügge and colleagues looked at brain connectivity and mental health data from nearly 500 people. In particular, they looked at the connectivity of the amygdala—a brain region well known for its importance in emotion and reward processing.

Summary: Study reveals a strong connection between certain bacteria residing in the gut and metabolites, small molecules found in the blood.

Source: Uppsala University.

There are strong links between bacteria living in the gut and the levels of small molecules in the blood known as metabolites. Such is the finding of a new study led by researchers from Uppsala University and Lund University, which is now published in the journal Nature Communications.

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC). The researcher’s findings are published in Nature Cancer.

“Pancreatic ductal adenocarcinoma is one of the most lethal cancers,” says the paper’s senior author Zhenkun Lou, Ph.D. Dr. Lou says while Poly-ADP-ribose-polymerase inhibitors (PARPi) are now an FDA-approved option for standard maintenance therapy for patients with metastatic PDAC who harbor pathogenic germline BRCA1/2 mutations, only about 10 percent of patients with PDAC harbor pathogenic mutations of the homologous recombination (HR) genes. “This leaves most patients missing out on this encouraging treatment strategy,” says Dr. Lou.

In this study, Dr. Lou and his colleagues found that the protein METTL16 may be a new biomarker for PARPi treatment, and that PDAC with elevated expression of METTL16, may benefit from PARPi treatment.

For decades the field of cryobiology was largely ignored and underfunded. However, in recent years, several advances were made and will enable the creation of massively transformative industries. One of these advances in rapid reheating and is pioneered by the Dayong Gao group. Here is the story.

Quantum computers and communication devices work by encoding information into individual or entangled photons, enabling data to be quantum securely transmitted and manipulated exponentially faster than is possible with conventional electronics. Now, quantum researchers at Stevens Institute of Technology have demonstrated a method for encoding vastly more information into a single photon, opening the door to even faster and more powerful quantum communication tools.

Typically, quantum communication systems “write” information onto a photon’s spin angular momentum. In this case, photons carry out either a right or left circular rotation, or form a quantum superposition of the two known as a two-dimensional qubit.

It’s also possible to encode information onto a photon’s orbital angular momentum —the corkscrew path that light follows as it twists and torques forward, with each photon circling around the center of the beam. When the spin and angular momentum interlock, it forms a high-dimensional qudit—enabling any of a theoretically infinite range of values to be encoded into and propagated by a single photon.

I am registering Posthuman as a religion in UK, and MVT (although evidence based) as a “religious belief” — which seems consistent with.gov requirements, since the Posthuman Movement started 1988 in UK. Why shouldn’t rational folk benefit from the same financial benefits awarded to promoters of Supernaturalism and religious daftness? Perhaps Transhumans should also consider this, or jointly with https://Posthuman.org? Any USA citizens interested in this approach? https://www.gov.uk/…/charitable…/charitable-purposes…

Posthuman Psychology, MVT research, World Philosophy, Software development.

The eccentric billionaire has said he’ll ask for an exemption to US sanctions on Iran to provide Spacelink internet access to the country.

Summary: The pioneering “soleus pushup” effectively elevates muscle metabolism for hours, even when sitting.

Source: University of Houston.

From the same mind whose research propelled the notion that “sitting too much is not the same as exercising too little,” comes a groundbreaking discovery set to turn a sedentary lifestyle on its ear: The soleus muscle in the calf, though only 1% of your body weight, can do big things to improve the metabolic health in the rest of your body if activated correctly.