Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.
The vaccines were administered after surgery to remove the tumor and are designed to train the body’s immune system to recognize and eliminate any remaining tumor cells. At the time of data cut-off (median of 34.7 months), all patients remained cancer-free.
The results of this Phase I trial were reported in Nature.
Three months after its launch from NASA’s Kennedy Space Center in Florida, the agency’s Europa Clipper has another 1.6 billion miles (2.6 billion kilometers) to go before it reaches Jupiter’s orbit in 2030 to take close-up images of the icy moon Europa with science cameras.
Meanwhile, a set of cameras serving a different purpose is snapping photos in the space between Earth and Jupiter. Called star trackers, the two imagers look for stars and use them like a compass to help mission controllers know the exact orientation of the spacecraft—information critical for pointing telecommunications antennas toward Earth and sending data back and forth smoothly.
In early December, the pair of star trackers (formally known as the stellar reference units) captured and transmitted Europa Clipper’s first imagery of space. The picture, composed of three shots, shows tiny pinpricks of light from stars 150 to 300 light-years away. The starfield represents only about 0.1% of the full sky around the spacecraft, but by mapping the stars in just that small slice of sky, the orbiter is able to determine where it is pointed and orient itself correctly.
The motivation behind the new study was to address these gaps in our understanding by leveraging the power of large-scale data. The researchers recognized that investigating the connection between genetic predisposition to dyslexia and brain structure in a very large sample could provide more robust and reliable insights than smaller, more traditional studies. They aimed to identify specific brain regions and white matter tracts that are associated with genetic risk for dyslexia, and to explore whether different genetic variants might influence distinct neural pathways.
“Thirty-five genetic variants that influence the chance of having dyslexia were already known from a very large study by the company 23andMe in the USA, carried out in over one million people. However, that study did not include brain MRI data. The new aspect of our study was to investigate the genetic variants in relation to brain structure in MRI data from thousands of people,” explained Clyde Francks (@clydefrancks), a professor at the Max Planck Institute for Psycholinguistics in Nijmegen and senior author of the study.
The researchers used two large datasets: the genetic data 23andMe and brain imaging data from over 30,000 adults in the UK Biobank. The 23andMe dataset helped identify genetic variants associated with dyslexia by comparing individuals who reported a dyslexia diagnosis to those who did not. These genetic variants were then used to calculate “polygenic scores” for individuals in the UK Biobank, reflecting their genetic predisposition to dyslexia.
The distribution of quantum computations is demonstrated between two photonically interconnected trapped-ion modules, using repeatable, deterministic teleported controlled-Z gates to perform Grover’s search algorithm.
Discover how Caltech’s groundbreaking research on ultrathin light sails is revolutionizing space travel. This video explains the innovative design, precise measurements, and surprising discoveries that are paving the way for interstellar propulsion. Dive into the science behind using laser-driven membranes to propel spacecraft and learn why this breakthrough is a game-changer for future space exploration.
Paper link: https://www.nature.com/articles/s4156… 00:00 Introduction 00:57 Experimental Innovations in Lightsail Design 03:56 Precision Measurement of Radiation Pressure 07:37 Future Directions, Implications, and a Relevant Discovery 11:06 Outro 11:16 Enjoy MUSIC TITLE: Starlight Harmonies MUSIC LINK: https://pixabay.com/music/pulses-star… Visit our website for up-to-the-minute updates: www.nasaspacenews.com Follow us Facebook: / nasaspacenews Twitter: / spacenewsnasa Join this channel to get access to these perks: / @nasaspacenewsagency #NSN #NASA #Astronomy#InterstellarLightsail #Caltech #SpaceExploration #BreakthroughStarshot #LaserPropulsion #Nanotechnology #SpaceTech #InterstellarTravel #LightsailDesign #Physics #Astrophysics #SpaceInnovation #RocketScience #FutureTech #LaserSail #PhotonPropulsion #SciTech #SpaceResearch #Astronomy #Innovation #ScienceNews #Interstellar #SpaceMission #LabResearch #Nanofabrication #EdgeScattering #RadiationPressure #Metamaterials #SpaceExplorationNews #NextGenTech.
Chapters: 00:00 Introduction. 00:57 Experimental Innovations in Lightsail Design. 03:56 Precision Measurement of Radiation Pressure. 07:37 Future Directions, Implications, and a Relevant Discovery. 11:06 Outro. 11:16 Enjoy.
A recent study led by quantum researchers at the Department of Energy’s Oak Ridge National Laboratory proved popular among the science community interested in building a more reliable quantum network.
The study, led by ORNL’s Hsuan-Hao Lu, details development of a novel quantum gate that operates between two photonic degrees of freedom—polarization and frequency. (Photonic degrees of freedom describe different properties of a photon that can be controlled and used to store or transmit information.) When combined with hyperentanglement, this new approach could enhance error resilience in quantum communication, helping to pave the way for future quantum networks.
Their work was published in the journal Optica Quantum.
Quantum spin liquids (QSLs) are fascinating and mysterious states of matter that have intrigued scientists for decades. First proposed by Nobel laureate Philip Anderson in the 1970s, these materials break the conventional rules of magnetism by never settling into a stable magnetic state, even at temperatures close to absolute zero.
Instead, the spins of the atoms within them remain constantly fluctuating and entangled, creating a kind of magnetic “liquid.” This unusual behavior is driven by a phenomenon called magnetic frustration, where competing forces prevent the system from reaching a single, ordered configuration.
QSLs are notoriously difficult to study. Unlike ordinary magnetic materials, they don’t show the usual signs of magnetic transitions, which makes it hard to detect and understand them using traditional techniques. As a result, their behavior has remained an elusive puzzle for researchers.
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion through enzymatic RNA degradation. Essentially, chemical energy is converted into mechanical motion by biasing the Brownian motion.
The DNA-nanoparticle motor uses the “burnt-bridge” Brownian ratchet mechanism. In this type of movement, the motor is propelled by the degradation (or “burning”) of the bonds (or “bridges”) it crosses along the substrate, essentially biasing its motion forward.
These nano-sized motors are highly programmable and can be designed for use in molecular computation, diagnostics, and transport.
Tags; #science #neuroscience #happiness #happiness #neurodegenerativediseases #disease #health #mentalhealth #sleep #neuroscientist #disease #education #success. ****************** About me: I am Shambhu Yadav, Ph.D., a research scientist at Harvard Medical School (Boston, MA, USA). I also work (for fun) as a Science Journalist, editor, and presenter on a YouTube channel. Science Communication is my passion.
*********************************************************** Disclaimer 1: The video content is for educational and informational purposes only, not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider regarding any medical condition. Do not disregard or delay seeking professional medical advice based on information from this video. Any reliance on the information provided is at your own risk. Disclaimer 2: The Diary Of A Scientist (DOAS) channel does not promote or encourage any unusual activities, and all content provided by this channel is meant for EDUCATIONAL purposes only.
*Credits and thanks** The video was recorded using iPhone and edited using Adobe Premiere Pro: a timeline-based and non-linear video editing software. Music source: Epidemic sound.
I shared this already. Here it is from Cell reversing diabetes type 1 with stem cells, reducing need for insulin shots.
Chemically induced stem-cell-derived islets were transplanted beneath the abdominal anterior rectus sheath in one patient with type 1 diabetes, resulting in tolerable safety and promising restoration of exogenous-insulin-independent glycemic control at 1-year follow-up.
