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My recently published perspective paper has been featured by GEN Genetic Engineering & Biotechnology News!

#biotechnology #genetherapy #syntheticbiology

Synthetic biology has the potential to upend existing paradigms of adeno-associated virus (AAV) production, helping to reduce the high costs of gene therapy and thus make it more accessible, according to a recent paper.

AAVs are an important vector for gene therapy, but AAV manufacturing is complex and expensive. Furthermore, first author Logan Thrasher Collins, a PhD candidate at Washington University in Saint Louis, tells GEN. “Many current industry approaches to enhancing AAV yields involve incremental process optimization. Synthetic biology has the potential to offer more radical improvements, yet is relatively underappreciated in the context of AAV production.”

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Expand (PITTSBURGH, Pa.) — One of the most consistent issues that disaster response teams face is blood shortages. These headaches, caused by short supply and perishability, make blood donations a constant push across the nation. CBS News reports that in Pennsylvania, scientists from the University of Pittsburgh School of Medicine and UPMC are making progress, and could see results within the decade.

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According to scientific reports, this study relies on studying the DNA of the bird known as “Dodo”, which lived on the island of Mauritius in the middle of the Indian Ocean until the late seventeenth century, and was unable to fly. It may seem like a fantasy, because the animal has been extinct for centuries, but scientists make it clear that their quest is based on very carefully studied steps.

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Do we make conscious decisions? Or are all of our actions predetermined? And if we don’t have free will, are we responsible for what we do? Modern neurotechnology is now allowing scientists to study brain activity neuron by neuron to try to determine how and when our brains decide to act. In this program, experts probe the latest research and explore the question of just how much agency we have in the world, and how the answer impacts our ethics, our behavior, and our society.

This program is part of the Big Ideas Series, made possible with support from the John Templeton Foundation.

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Original Program Date: May 30, 2015

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