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“People on metformin have 30% lower rates of almost every kind of cancer. It delays cognitive decline. Even people with diabetes who are obese and have more disease to start with but are on metformin have lower mortality rates than people without diabetes who aren’t on the drug.”

What he says is born out in numerous studies. Overall, this safe, super-cheap, decades-old drug not only treats diabetes, but it also seems to delay and compress the years of chronic illness associated with the final stage of life and extend what geroscientists call the “healthspan.”

Metformin is just one of many medications, including other old ones and some brand new inventions, that academic researchers and biotech startups are exploring to slow, stop, or perhaps even reverse aging.

AI might not take your job any time soon, but companies are already using it to help them decide who to lay off.

That’s according to a November Capterra survey of 300 US human resources leaders, which found that 98% of respondents plan to use software and algorithms to help them make any layoff decisions in 2023.

While many companies have access to a wide range of employee data — including information on employee attendance, pay, and experience — the HR leaders said “skills” and “performance” data would be most likely to be used in a layoff decision, with 70% of the leaders saying each of these would be considered.

Several studies have predicted that the water splitting reaction could be catalyzed by certain groups of 2D materials—each measuring just a few atoms thick. One particularly promising group are named 2D Janus materials, whose two sides each feature a different molecular composition.

Through new calculations detailed in The European Physical Journal B, Junfeng Ren and colleagues at Shandong Normal University in China present a new group of four 2D Janus materials, which could be especially well suited to the task.

Since hydrogen releases an abundance of energy when combusted, with only water as a byproduct, it is now widely seen as an excellent alternative to fossil fuels. Splitting involves a , where and holes participate in reduction and oxidation reactions.

For the first time, a researcher at the University of Delaware College of Health Sciences in collaboration with a team at the National Institute on Aging, a division of the National Institutes of Health, has determined that the naturally occurring dietary supplement known as nicotinamide riboside (NR) can enter the brain.

The discovery was made by Christopher Martens, assistant professor of kinesiology and applied physiology and director of the Delaware Center for Cognitive Aging Research, and Dr. Dimitrios Kapogiannis, a senior investigator at the National Institute on Aging. The finding is significant because it supports the idea that NR, upon reaching the brain, can alter the metabolism of relevant biological pathways involved in like Alzheimer’s. Their work was recently published in the journal Aging Cell.

Upon consumption, NR is readily converted into nicotinamide adenine dinucleotide (NAD+), which is critical to cellular repair and the repair of damaged DNA.

West Virginia University physicists have made a breakthrough on an age-old limitation of the first law of thermodynamics.

Paul Cassak, professor and associate director of the Center for KINETIC Plasma Physics, and graduate research assistant Hasan Barbhuiya, both in the Department of Physics and Astronomy, are studying how energy gets converted in superheated plasmas in .

Their findings, published in Physical Review Letters, will revamp scientists’ understanding of how plasmas in space and laboratories get heated up, and may have a wide variety of further applications across and other sciences.