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At Blueprint we’ve explored and evaluated hundreds of anti-aging therapies.

Recently, we had a daring idea: what if my father, son and I completed the world’s first ever multi-generational plasma exchange?

Plasma is the yellowish, liquid part of your blood. There is emerging evidence that plasma exchanges may offer various health benefits.

Nervous but excited, we travelled to a transfusion centre in Dallas Texas to make it happen.

🧪 WHAT IS BLUEPRINT
I’ve invested millions of dollars building the world’s leading anti-aging protocol, becoming the most measured human in history. Blueprint is an algorithm, built by science, that takes better care of me than I can myself.

And it’s available to you for free. Check out the Blueprint website for recipes, exercise, and other protocols. Become the next evolution of human.

Perspective from a very-educated layman. Er, laywoman.


This is Hello, Computer, a series of interviews carried out in 2023 at a time when artificial intelligence appears to be going everywhere, all at once.

Sabine Hossenfelder is a German theoretical physicist, science communicator, author, musician, and YouTuber. She is the author of Lost in Math: How beauty leads physics astray, which explores the concept of elegance in fundamental physics and cosmology, and of Existential Physics: A scientist’s guide to life’s biggest questions.

Sabine has published more than 80 research papers in the foundations of physics, from cosmology to quantum foundations and particle physics. Her writing has appeared in Scientific American, Nautilus, The New York Times, and The Guardian.

Sabine also works as a freelance popular science writer and runs the YouTube channel Science Without the Gobbledygook, where she talks about recent scientific developments and debunks hype, and a separate YouTube channel for music she writes and records.

The other day a friend proudly told me she wrote a heartwarming graduation card to her teenage son. “Okay,” she confessed. “I

How long was your card? I asked her.


Not only that, but many also couldn’t even generate a topic on their own. They lacked creativity to dream up their own ideas, much less the critical thinking skills to put themselves in the shoes of their audience, imagining what would land. But they all had 4.0 GPAs or higher and came from private schools in Orange County and LA, reflecting our watered-down educational system.

And now we’re being told ChatGPT is a boon for our students?

Despite these concerns, our best days are ahead of us. As a positive futurist, I see the AI surge as a wakeup call. Especially in corporate America. For too long, we’ve outsourced too much. As just one example, the COVID-19 pandemic exposed how reliant we are on countries like China for manufacturing, including our critical medical supply chain.

According to the Financial Times, Meta is in talks with Magic Leap, an AR headset company, to look into licensing the latter’s tech.

Meta is reportedly in talks with a company called Magic Leap with an eye to a partnership that could see Meta developing its alternative reality (AR) headset in the future.

According to the Financial Times, the two are negotiating a multi-year intellectual property (IP) and manufacturing alliance. The report’s timing is significant for a few reasons.

With LIMA, Meta’s AI researchers introduce a new language model that achieves GPT-4 and Bard level performance in test scenarios, albeit fine-tuned with relatively few examples.

LIMA stands for “Less is More for Alignment,” and the name hints at the model’s function: It is intended to show that with an extensively pre-trained AI model, a few examples are sufficient to achieve high-quality results.

Few examples in this case means that Meta manually selected 1,000 diverse prompts and their output from sources such as other research papers, WikiHow, StackExchange, and Reddit.

Summary: Scientists present a hypothesis dubbed “Cytoelectric Coupling” suggesting electrical fields within the brain can manipulate neuronal sub-cellular components, optimizing network stability and efficiency. They propose these fields allow neurons to tune the information-processing network down to the molecular level.

Comparatively, this process is akin to households arranging their TV setup for optimal viewing experience. The theory, open for testing, could significantly enhance our understanding of the brain’s inner workings.

Summary: Neurons in the hippocampus vary in function depending on their exact genetic identity. The study revealed these neurons, once believed to be homogeneous, are quite diverse and encode task-related information differently based on their location. This newfound understanding of neuronal diversity could lead to better comprehension of brain functions, memory capacity, and potentially advance disease treatment strategies.

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