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A powerful plant-derived toxin with a unique way of killing harmful bacteria has been identified as one of the most promising new antibiotics in decades.

Albicidin, a new antibiotic, is produced by the plant pathogen Xanthomonas albilineans, responsible for causing sugar cane’s destructive leaf scald disease. The toxin is believed to aid the pathogen’s spread by attacking the plant. Albicidin has been shown to be highly effective against harmful bacteria, including drug-resistant superbugs such as E. coli and S. aureus.

Despite its antibiotic potential and low toxicity in pre-clinical experiments, pharmaceutical development of albicidin has been hampered because scientists did not know precisely how it interacted with its target, the bacterial enzyme DNA.

In a study published in the journal Cell Stem Cell on February 2, researchers show that brain organoids—clumps of lab-grown neurons—can integrate with rat brains and respond to visual stimulation like flashing lights.

Decades of research has shown that we can transplant individual human and rodent neurons into rodent brains, and, more recently, it has been demonstrated that human brain organoids can integrate with developing rodent brains. However, whether these organoid grafts can functionally integrate with the visual system of injured adult brains has yet to be explored.

“We focused on not just transplanting individual cells, but actually transplanting tissue,” says senior author H. Isaac Chen, a physician and Assistant Professor of Neurosurgery at the University of Pennsylvania. “Brain organoids have architecture; they have structure that resembles the brain. We were able to look at individual neurons within this structure to gain a deeper understanding of the integration of transplanted organoids.”

Researchers are studying hibernating Arctic ground squirrels with the goal of harnessing the benefits of this odd natural state to protect astronauts’ health on long-duration space missions.

Hibernation is not just sleep. In fact, it’s quite different from sleep. While we sleep, our brains fire up and become highly active; in hibernation, on the contrary, brain activity completely slows down. The body temperature of hibernating animals also drops, in some cases close to the freezing point, cells stop dividing and heart rate decreases to two beats per minute.

As fantastic as this may seem this is not an impossible occurrence.


Before Einstein, time travel was just a story, but his calculations led us into the quantum world and gave us a more complicated picture of time. Kurt Godel found that Einstein’s equations made it possible to go back in time. What’s up? None of the ideas about how to go back in time were ever physically possible.

Before sending a particle back in time, scientists from ETH Zurich, Argonne National Laboratory, and Moscow Institute of Physics and Technology asked, Why stick to physical grounds?

Many laws of physics treat the future and the past as if they are one thing. The second rule of thermodynamics says that in a closed system, order gives way to chaos (or entropy). When you scramble an egg to make an omelet, you add a lot of chaos to the egg, which was a closed system before.

Results from a complex new analysis support cosmologists’ suspicions that something is missing from our understanding of the universe.

For the most part, our standard theory of cosmology fits observations like a glove. With just a handful of ingredients, scientists can explain the patchy pattern of the cosmic microwave background (CMB) — the relic radiation from the universe’s primordial age — and how the nearly uniform soup it came from transformed into the Swiss cheese of galaxy clusters and cosmic voids we see today.

But some nagging problems remain. The most touted is the Hubble tension, a discrepancy between how fast the universe appears to be expanding today and how fast it “should” be expanding, based on what we see in the early universe. But there’s another, more subtle discrepancy: Today’s universe is too smooth.

Personal visual development based on the novel “Rendezvous with Rama”, written by Arthur C. Clarke.
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