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Nov 14, 2022

Beer Ingredient May Inhibit Clumping of Alzheimerโ€™s Protein

Posted by in categories: biotech/medical, chemistry, food, health, neuroscience

Cheers!

๐๐ž๐ž๐ซ ๐ˆ๐ง๐ ๐ซ๐ž๐๐ข๐ž๐ง๐ญ ๐Œ๐š๐ฒ ๐ˆ๐ง๐ก๐ข๐›๐ข๐ญ ๐‚๐ฅ๐ฎ๐ฆ๐ฉ๐ข๐ง๐  ๐จ๐Ÿ ๐€๐ฅ๐ณ๐ก๐ž๐ข๐ฆ๐ž๐ซโ€™๐ฌ ๐๐ซ๐จ๐ญ๐ž๐ข๐ง

๐˜ฝ๐™š๐™š๐™ง ๐™ž๐™จ ๐™ค๐™ฃ๐™š ๐™ค๐™› ๐™ฉ๐™๐™š ๐™ค๐™ก๐™™๐™š๐™จ๐™ฉ ๐™–๐™ฃ๐™™ ๐™ข๐™ค๐™จ๐™ฉ ๐™ฅ๐™ค๐™ฅ๐™ช๐™ก๐™–๐™ง ๐™—๐™š๐™ซ๐™š๐™ง๐™–๐™œ๐™š๐™จ ๐™ž๐™ฃ ๐™ฉ๐™๐™š ๐™ฌ๐™ค๐™ง๐™ก๐™™, ๐™ฌ๐™ž๐™ฉ๐™ ๐™จ๐™ค๐™ข๐™š ๐™ฅ๐™š๐™ค๐™ฅ๐™ก๐™š ๐™ก๐™ค๐™ซ๐™ž๐™ฃ๐™œ ๐™–๐™ฃ๐™™ ๐™ค๐™ฉ๐™๐™š๐™ง๐™จ ๐™๐™–๐™ฉ๐™ž๐™ฃ๐™œ ๐™ฉ๐™๐™š ๐™™๐™ž๐™จ๐™ฉ๐™ž๐™ฃ๐™˜๐™ฉ, ๐™—๐™ž๐™ฉ๐™ฉ๐™š๐™ง ๐™ฉ๐™–๐™จ๐™ฉ๐™š ๐™ค๐™› ๐™ฉ๐™๐™š ๐™๐™ค๐™ฅ๐™จ ๐™ช๐™จ๐™š๐™™ ๐™ฉ๐™ค ๐™›๐™ก๐™–๐™ซ๐™ค๐™ง ๐™ž๐™ฉ๐™จ ๐™ข๐™–๐™ฃ๐™ฎ ๐™ซ๐™–๐™ง๐™ž๐™š๐™ฉ๐™ž๐™š๐™จ. ๐˜ฝ๐™ช๐™ฉ ๐™–๐™ฃ ๐™š๐™จ๐™ฅ๐™š๐™˜๐™ž๐™–๐™ก๐™ก๐™ฎ โ€œ๐™๐™ค๐™ฅ๐™ฅ๐™ฎโ€ ๐™—๐™ง๐™š๐™ฌ ๐™ข๐™ž๐™œ๐™๐™ฉ ๐™๐™–๐™ซ๐™š ๐™ช๐™ฃ๐™ž๐™ฆ๐™ช๐™š ๐™๐™š๐™–๐™ก๐™ฉ๐™ ๐™—๐™š๐™ฃ๐™š๐™›๐™ž๐™ฉ๐™จ. ๐™๐™š๐™˜๐™š๐™ฃ๐™ฉ ๐™ง๐™š๐™จ๐™š๐™–๐™ง๐™˜๐™ ๐™ฅ๐™ช๐™—๐™ก๐™ž๐™จ๐™๐™š๐™™ ๐™ž๐™ฃ ๐˜ผ๐˜พ๐™Ž ๐˜พ๐™๐™š๐™ข๐™ž๐™˜๐™–๐™ก ๐™‰๐™š๐™ช๐™ง๐™ค๐™จ๐™˜๐™ž๐™š๐™ฃ๐™˜๐™š ๐™ง๐™š๐™ฅ๐™ค๐™ง๐™ฉ๐™จ ๐™ฉ๐™๐™–๐™ฉ ๐™˜๐™๐™š๐™ข๐™ž๐™˜๐™–๐™ก๐™จ ๐™š๐™ญ๐™ฉ๐™ง๐™–๐™˜๐™ฉ๐™š๐™™ ๐™›๐™ง๐™ค๐™ข ๐™๐™ค๐™ฅ ๐™›๐™ก๐™ค๐™ฌ๐™š๐™ง๐™จ ๐™˜๐™–๐™ฃ, ๐™ž๐™ฃ ๐™ก๐™–๐™— ๐™™๐™ž๐™จ๐™๐™š๐™จ, ๐™ž๐™ฃ๐™๐™ž๐™—๐™ž๐™ฉ ๐™ฉ๐™๐™š ๐™˜๐™ก๐™ช๐™ข๐™ฅ๐™ž๐™ฃ๐™œ ๐™ค๐™› ๐™–๐™ข๐™ฎ๐™ก๐™ค๐™ž๐™™ ๐™—๐™š๐™ฉ๐™– ๐™ฅ๐™ง๐™ค๐™ฉ๐™š๐™ž๐™ฃ๐™จ, ๐™ฌ๐™๐™ž๐™˜๐™ ๐™ž๐™จ ๐™–๐™จ๐™จ๐™ค๐™˜๐™ž๐™–๐™ฉ๐™š๐™™ ๐™ฌ๐™ž๐™ฉ๐™ ๐˜ผ๐™ก๐™ฏ๐™๐™š๐™ž๐™ข๐™š๐™งโ€™๐™จ ๐™™๐™ž๐™จ๐™š๐™–๐™จ๐™š (๐˜ผ๐˜ฟ).

Continue reading “Beer Ingredient May Inhibit Clumping of Alzheimerโ€™s Protein” »

Nov 14, 2022

Lab discovers new pathway for antimicrobial peptides

Posted by in category: biotech/medical

Researchers in the Princeton University Department of Chemistry have discovered a new multi-step pathway through which bacteria found in the mammalian gut produce antimicrobial peptides.

The newly identified biosynthetic pathway transforms a biologically inert peptide into structurally complex antibiotics, which they call enteropeptins. Enteropeptins are a class of ribosomally synthesized peptide , referred to as RiPPs.

The core structure of these products is synthesized by the ribosome, which is limited to the 20 canonical amino acids. The Mo Lab discovered and characterized new metalloenzymes capable of converting arginine, a canonical amino acid, into N-methylornithine, a noncanonical amino acid, within enteropeptin.

Nov 14, 2022

Worldโ€™s largest solar telescope array is now complete

Posted by in category: space

Chinaโ€™s Daocheng Solar Radio Telescope is among a suite of instruments the country has built in the past three years to study the Sun.

Nov 14, 2022

The Gold In Our Galaxy May Be 10 Billion Years Old, Say Scientists

Posted by in categories: physics, space, supercomputing

The hundreds of gold-rich stars discovered in our Milky Way galaxy may have come from smaller galaxies that merged 10 billion years ago, according to new simulations by a supercomputer.

Using the ATERUI II supercomputer in the Center for Computational Astrophysics at the National Astronomical Observatory of Japan, scientists at Tohoku University and the University of Notre Dame developed new simulations of galaxy formation with the highest resolution yet.

The paper was published this week in the Monthly Notices of the Royal Astronomical Society.

Nov 14, 2022

Researchers discover unique peptides with anti-cancer potential

Posted by in categories: biotech/medical, chemistry

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

The research was led by Professor Ashraf Brik and post-doctoral fellows Dr. Ganga B. Vamisetti and Dr. Abbishek Saha from the Schulich Faculty of Chemistry at the Technionโ€”Israel Institute of Technology in Haifa, along with Professor Nabieh Ayoub from the Technionโ€™s Faculty of Biology and Professor Hiroaki Suga from the University of Tokyo.

Peptides are short chains of amino acids linked by , the name given to formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule.

Nov 14, 2022

Ultra-thin smartphone touchscreens could be printed like a newspaper

Posted by in categories: materials, mobile phones

face_with_colon_three circa 2020.


Scientists in Australia have developed a new type of electronic material that is touch-responsive and just a fraction of the thickness of current smartphone screens. This could see it one day find use in next-generation mobile devices, and because of its incredible thinness and flexibility, could be manufactured at large scale using roll-to-roll (R2R) processing like a printed newspaper.

The breakthrough comes from researchers at RMIT University, who began with a material commonly used in todayโ€™s mobile touchscreens called indium-tin oxide. This transparent material is highly conductive but does have its shortcomings, chiefly that it is very brittle, so the team sought to give it better pliability by greatly reducing its thickness.

Continue reading “Ultra-thin smartphone touchscreens could be printed like a newspaper” »

Nov 14, 2022

Recent searches for light fermionic dark matter by the PandaX-4T collaboration

Posted by in categories: cosmology, particle physics

Teams of astrophysicists worldwide are trying to observe different possible types of dark matter (DM), hypothetical matter in the universe that does not emit, absorb or reflect light and would thus be very difficult to detect. Fermionic DM, however, which would be made of fermions, has so far been primarily explored theoretically.

The PandaX Collaboration, a large consortium of researchers in China involved in the PandaX-4T experiment, has recently carried out a study aimed at extending the sensitive window for experiments aimed at directly detecting fermionic DM from above GeV to MeV or even keV ranges.

The team recently published two papers in Physical Review Letters outlining the results of the two searches for the absorption of fermionic DM using data gathered as part of the Panda X-4T experiment, a large-scale research effort aimed at detecting DM using a dual-phase time projection chamber (TPC) in China.

Nov 14, 2022

Meet Orbit, the Interactive Robot That Looks to Help Children With Autism Spectrum Disorders Develop Social Skills

Posted by in category: robotics/AI

Orbit, an interactive robot, helps teach children on the autism spectrum to develop social appropriateness and emotion via storytelling, physical interaction, and visual communication.

The hand-sized robot smiles and encourages users to press a button on its back, reacting with a beaming smile if pressed gently, and with a sad face if the interaction is too hard.

Continue reading “Meet Orbit, the Interactive Robot That Looks to Help Children With Autism Spectrum Disorders Develop Social Skills” »

Nov 14, 2022

Mapping Brain Connections Reinforces Theories On Human Cognition

Posted by in categories: mapping, neuroscience

17:12 minutes.

After decades of research using sophisticated brain imaging, thereโ€™s a growing consensus among neuroscientists that understanding the connections between brain regions may be even more important than the functions of the regions themselves. When it comes to understanding human cognition, the whole is greater than the sum of its parts.

Nov 14, 2022

Is Physical Law an Alien Intelligence?

Posted by in categories: alien life, existential risks, mobile phones, particle physics, singularity

Perhaps Arthur C. Clarke was being uncharacteristically unambitious. He once pointed out that any sufficiently advanced technology is going to be indistinguishable from magic. If you dropped in on a bunch of Paleolithic farmers with your iPhone and a pair of sneakers, youโ€™d undoubtedly seem pretty magical. But the contrast is only middling: The farmers would still recognize you as basically like them, and before long theyโ€™d be taking selfies. But what if life has moved so far on that it doesnโ€™t just appear magical, but appears like physics?

After all, if the cosmos holds other life, and if some of that life has evolved beyond our own waypoints of complexity and technology, we should be considering some very extreme possibilities. Todayโ€™s futurists and believers in a machine โ€œsingularityโ€ predict that life and its technological baggage might end up so beyond our ken that we wouldnโ€™t even realize we were staring at it. Thatโ€™s quite a claim, yet it would neatly explain why we have yet to see advanced intelligence in the cosmos around us, despite the sheer number of planets it could have arisen onโ€”the so-called Fermi Paradox.

For example, if machines continue to grow exponentially in speed and sophistication, they will one day be able to decode the staggering complexity of the living world, from its atoms and molecules all the way up to entire planetary biomes. Presumably life doesnโ€™t have to be made of atoms and molecules, but could be assembled from any set of building blocks with the requisite complexity. If so, a civilization could then transcribe itself and its entire physical realm into new forms. Indeed, perhaps our universe is one of the new forms into which some other civilization transcribed its world.