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The journal Nature published a groundbreaking new study by world-renowned Stanford neuroscientist Sergiu Pasca involving the transfer of human brain organoids into the brains of rats. Insoo Hyun, Director of the Center for Life Sciences and Public Learning at the Museum of Science, speaks candidly with Dr. Pasca about his research. Why did he do it? How might this uncover the mysteries of psychiatric disorders? And the Big Question we are all wondering about – can these rats ever develop “human-like” consciousness? Together they demystify the science.

00:33 Dr. Sergiu Pasca’s Romanian roots.
00:55 Why is Dr. Pasca’s work important for Psychiatry?
04:14 Dr. Pasca’s work with human brain organoids.
06:14 Challenges with using animal brains when trying to unlock mysteries of human psychiatric disorders.
07:13 Reason for Dr. Pasca’s latest research transplanting human brain organoids into rat brains.
08:47 How the human brain organoid transplantation into a rat brain is accomplished.
10:19 What Dr. Pasca learned from his experiment and its importance.
12:02 Brain cells’ amazing ability to take over and organize themselves in appropriate environments.
13:03 Will animals with human brain organoids in their brain develop human-like consciousness?
17:30 Will manipulating human neurons in a rat change the behavior of the rat?
19:43 Application of rat experiment findings for human patients.
22:07 The ethics and regulation of using animals in scientific research.
25:25 Why context matters in research of transplanting human brain organoids into rat brains and the challenge of people backfilling science they might not understand with mythology and science fiction.
32:28 Dr. Pasca’s inspiration to work so hard to unlock the mysteries of psychiatric disorders.

“The Big Question” is a production of the Museum of Science, Boston.

Learn more about the Museum of Science Life Sciences and Public Learning: https://www.mos.org/explore/center-for-life-sciences.

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You may already know that it’s important to wash your hands, wear a face mask and avoid sick people while neutropenic.

But is there anything else you should — or should not — be doing to avoid infections when you’re immunocompromised by a low white blood cell count during or after cancer treatment?

We spoke with internal medicine expert Carmen Escalante, M.D., for insight. Here are five precautions she shares with immunocompromised patients and their caregivers.

Welcome back to Chain Reaction, a podcast that interviews newsmakers in crypto to better understand the tech behind the hype and the people working to build a decentralized future.

For this week’s episode, Jacquelyn interviewed Emin Gün Sirer, the founder and CEO of Ava Labs.

Ava Labs has raised a total of about $640 million, according to Crunchbase, and is backed by firms like a16z and Polychain Capital. In recent months, Ava Labs has announced a number of partnerships with major brands and companies, like Amazon Web Services, which TechCrunch covered exclusively.

Neuroscience playlist.


Instructor: Nancy Kanwisher View the complete course: https://ocw.mit.edu/9-13S19 YouTube Playlist: This course surveys the core perceptual and cognitive abilities of the human mind and explores how they are implemented in the brain… NOTE: * Lecture 3. Master Class: Human Brain Dissection (in-class dissection—video not recorded) * NOTE: Lecture 12: Brain-Machine Interface with Guest Lecturer Michael Cohen is unavailable * Lecture 14: New Methods Applied to Number (student breakout groups—video not recorded) * Lecture 17: MEG Decoding and RSA (video not recorded) * Lecture 19: Language II (class canceled—video not recorded) * Lecture 22: Experimental Design (student breakout groups—video not recorded) * Lecture 23: Deep Networks (2021) (video will be added soon) License: Creative Commons BY-NC-SA More information at https://ocw.mit.edu/terms More courses at https://ocw.mit.edu Support OCW at http://ow.ly/a1If50zVRlQ We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.