Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 36

The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known to play a key role in supporting the development of synapses and neural circuits (i.e., connections between neurons). Mutations in this gene have been linked to various learning disabilities, including intellectual disabilities, speech and language delays, autism spectrum disorder (ASD), and epilepsy.

Researchers at the Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology recently carried out a study aimed at better understanding the via which the SYNGAP1 gene contributes to healthy cognitive function. Their findings, published in Nature Communications, suggest that the autonomous expression of this gene in the cortical excitatory neurons of mice promotes the animals’ cognitive abilities via the assembly of long-range integrating sensory and motor information.

“Our paper builds on our ongoing research into how major risk genes for mental health disorders, including autism, regulate brain organization and function,” Gavin Rumbaugh, senior author of the paper, told Medical Xpress. “The field knows the major risk genes that directly contribute to cognitive and behavioral impairments that lead to diagnosable forms of autism and related neuropsychiatric disorders in humans.

Read more | >

ICEPS transplantation for LSCD was found to be safe throughout the study period. A larger clinical trial is planned to further investigate the efficacy of the procedure.

Read more | >

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life—how enzymes are able to speed up life-sustaining biochemical reactions so dramatically. Their findings could impact fields ranging from basic science to drug discovery, and provoke a rethinking of how science is taught in the classroom.

“When I say enzymes speed up reactions, I mean as in a trillion-trillion times faster for some reactions,” noted senior author of the study, Dan Herschlag, professor of biochemistry in the School of Medicine. “Enzymes are really remarkable little machines, but our understanding of exactly how they work has been lacking.”

There are lots of ideas and theories that make sense, Herschlag said, but biochemists have not been able to translate those ideas into a specific understanding of the chemical and physical interactions responsible for enzymes’ enormous reaction rates. As a result, biochemists don’t have a basic understanding and, therefore, have been unable to predict rates or design new enzymes as well as nature does, an ability that would be impactful across industry and medicine.

Read more | >

The words “optimal” and “optimize” derive from the Latin “optimus,” or “best,” as in “make the best of things.” Alessio Figalli, a mathematician at the university ETH Zurich, studies optimal transport: the most efficient allocation of starting points to end points. The scope of investigation is wide, including clouds, crystals, bubbles and chatbots.

Dr. Figalli, who was awarded the Fields Medal in math that is motivated by concrete problems found in nature. He also likes the discipline’s “sense of eternity,” he said in a recent interview. “It is something that will be here forever.” (Nothing is forever, he conceded, but math will be around for “long enough.”) “I like the fact that if you prove a theorem, you prove it,” he said. “There’s no ambiguity, it’s true or false. In a hundred years, you can rely on it, no matter what.”

The study of optimal transport was introduced almost 250 years ago by Gaspard Monge, a French mathematician and politician who was motivated by problems in military engineering. His ideas found broader application solving logistical problems during the Napoleonic Era — for instance, identifying the most efficient way to build fortifications, in order to minimize the costs of transporting materials across Europe.

Read more | >

A team of microbiologists, chemists and pharmaceutical specialists at Shandong University, Guangzhou Medical University, Second Military Medical University and Qingdao University, all in China, has developed an AI model that generates antimicrobial peptide structures for screening against treatment-resistant microbes.

In their study published in the journal Science Advances, the group developed a compression method to reduce the number of elements needed in training data for an AI system, which helped to reduce diversification issues with current AI models.

Prior research has suggested that drug-resistant microbes are one of the most pressing problems in medical science. Researchers around the world have been looking for new ways to treat people infected with such microbes—one approach involves developing , which work by targeting bacterial membranes.

Read more | >

A cafe in Finland has created an AI-coffee blend. From bean selection to packaging design, watch this report to see how the future of coffee is brewing.

#techitout #technology #tech.

About Channel:

WION The World is One News examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim is to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to world politics. People are tired of biased reportage and we stand for a globalized united world. So for us, the World is truly One.

Continue reading “Brewing The Perfect Cup Of Coffee With AI | Tech It Out | WION” | >

Related: Firefly’s Blue Ghost lunar lander leaves Earth orbit to head for the moon

Blue Ghost launched Jan. 15 atop a SpaceX Falcon 9 rocket. The lander’s mission, called “Ghost Riders in the Sky,” is part of NASA’s Commercial Lunar Payload Services (CLPS) program. Blue Ghost is carrying 10 science and technology experiments for the agency, which wants to better understand the lunar environment before sending astronauts back to the moon via its Artemis program.

Blue Ghost will spend the next 16 days in lunar orbit, if all goes to plan. It will conduct additional engine burns to circularize its path around Earth’s nearest neighbor, then attempt a landing in the Mare Crisium (“Sea of Crises”) region of the moon’s near side on March 2.

Read more | >

A groundbreaking study reveals that Alpha Centauri’s particles are already making their way into our solar system, traveling across the cosmic highway that connects star systems. These particles, ejected from the nearest stellar neighbor to Earth, could be carrying valuable insights about distant worlds and the forces that shape our galaxy.

Read more | >