Lifeboat Foundation

Researchers have developed a metasurface device that can display three types of images depending on the illumination light. The three-channel device could be used as an anticounterfeiting measure or offer a new way to securely deliver encrypted information.

“Metasurfaces are artificial materials with tiny nanostructures that can be used to manipulate light,” said research team member Qi Dai from Wuhan University in China. “In this work, we exploited both the size and orientation of the nanostructures to design a metasurface with three working modes.”

The researchers describe the new device in Optics Express. They also showed that depending on the light used, the metasurface would generate a holographic image or a structural-color nanoprinting image with or without polarization-dependent watermarks.

Neurodegenerative diseases—like amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease), Alzheimer’s, and Parkinson’s—are complicated, chronic ailments that can present with a variety of symptoms, worsen at different rates, and have many underlying genetic and environmental causes, some of which are unknown. ALS, in particular, affects voluntary muscle movement and is always fatal, but while most people survive for only a few years after diagnosis, others live with the disease for decades. Manifestations of ALS can also vary significantly; often slower disease development correlates with onset in the limbs and affecting fine motor skills, while the more serious, bulbar ALS impacts swallowing, speaking, breathing, and mobility. Therefore, understanding the progression of diseases like ALS is critical to enrollment in clinical trials, analysis of potential interventions, and discovery of root causes.

However, assessing disease evolution is far from straightforward. Current clinical studies typically assume that health declines on a downward linear trajectory on a symptom rating scale, and use these linear models to evaluate whether drugs are slowing disease progression. However, data indicate that ALS often follows nonlinear trajectories, with periods where symptoms are stable alternating with periods when they are rapidly changing. Since data can be sparse, and health assessments often rely on subjective rating metrics measured at uneven time intervals, comparisons across patient populations are difficult. These heterogenous data and progression, in turn, complicate analyses of invention effectiveness and potentially mask disease origin.

Continue reading “Machine-learning method shows neurodegenerative disease can progress in newly identified patterns” »

Additionally, epigenetic changes were suggested to be a possible link [30, 31] between adverse childhood experiences and mortality as well as higher morbidity burden in late life [32]. It was proposed that this link could be mediated by health-adverse coping mechanisms (activated as a result of high levels of anxiety and depression) that are associated with adverse childhood experiences [33]. Some of these coping strategies, such as smoking, alcohol abuse and and a high BMI resulting from unhealthy eating habits, were shown to be associated with DNAmAA in some studies [34,35,36]. However, these results were not unequivocally replicated [37,38,39] (reviewed in ref. [40]).

Previous studies that examined the relationship between DNAmAA and stress operationalized stress as low socioeconomic status (SES) [41, 42], (childhood) trauma [26, 43,44,45], racial discrimination [46], or exposure to violence [47]. Many previous studies on the topic focused on changes in DNAm age during childhood as this period is known to be particularly prone to stress-related epigenetic changes [29].

In contrast, in this work we focus on older age which was shown to be the second most vulnerable phase in a person’s life in terms of epigenetics [29]. As epigenetic modifications remain even after the psychological stimulus has ceased there is the possibility of cumulating effects on the epigenome exerted by repeated psychological stressors [29]. Specifically, we analyzed the association between the amount of experienced stress (measured by Cohen’s Perceived Stress Scale [PSS] [48]) and several DNAm age estimators (i.e. the 7-CpG clock [49], Horvath’s clock [50], Hannum’s clock [51], PhenoAge [34], GrimAge [52]) in 1,100 older adults. While the PSS represents a well-established marker of perceived stress [48], to our knowledge it has not been investigated in the context of epigenetic aging before. While we were able to replicate well-established associations with perceived stress, none of the five epigenetic clocks analyzed in the current study were associated with the perception of stress.

After doubts grew, blockbuster Nature paper is withdrawn over objections of study team.

This is NASA’s first major step to keeping us safe from killer asteroids.

face_with_colon_three circa 2021.

Most of the colors we see around us are produced by the reflection of light from pigments. Yet there is another type of color called “structural color,” produced when light is reflected off the special microstructure of a surface. Structural color is what makes the surface of soap bubbles iridescent and the body of a jewel beetle appear to glitter. While pigmented colors have the disadvantage of fading due to ultraviolet rays, structural colors retain their appearance as long as the microstructure remains intact. Associate Professor Michinari Kohri of Chiba University is working to artificially reproduce these structural colors. Taking a hint from the structural colors of peacock and turkey feathers, he has succeeded in reproducing the microstructure that gives rise to the colors and is now working on the development of special ink that will not fade.

So one treated rat made it to 45 months which is 113 for people. A 2nd trial is underway to try and increase these results. Also, the human topical test for E5 is just for skin rejuvenation, not fro full rejuvenation or lifespan increase for people.

In this video we report on the August 2022 update from Dr. Katcher’s experiment with E5 along with some other details about the book launch in other languages, the new experiment and topical E5 for humans!

Continue reading “Dr Katcher’s E5 Experiment September 2022 Update | Review” »

A new theory disputes a widely accepted claim about the existence of life on other planets.

The equivalence of life on Earth may hold the key to determining life existence on other planets according to a recent study published by Cambridge University Press.

Scientists have often questioned if the existence of life on Earth can tell us about abiogenesis, or the origin of life from inorganic substances, on other planets. Therefore the new insights may provide a fresh boost of understanding in the field.

Save your solar panels from the shade.

Currently, solar power accounts for 3.3 percent of the total energy produced in the US, and it has become the fastest-growing source of clean energy in the country. The National Renewable Energy Laboratory estimates that by 2050, the share of solar energy in America’s total electricity production could reach 45 percent. However, in order to achieve this milestone, solar energy experts will have to make photovoltaic systems more efficient and advanced than ever.

Continue reading “Our solar power dreams are threatened by shadows, we shouldn’t ignore them for long” »