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Physicists have built the first-ever lab model of a black hole bomb, a decades-old theory where spinning energy amplifies until it explodes.
Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.
A Phase I clinical trial, whose results have been published in the journal Blood, reveals that this new CAR-T30 therapy promotes the expansion of memory T cells, leading to long-lasting responses and improved clinical outcomes in treated patients.
Hodgkin lymphoma and other CD30+ lymphomas have posed a significant challenge to the medical community, particularly in refractory or relapsed cases where conventional treatments have so far shown limited efficacy.
As the world races to build the first commercial nuclear fusion plant, engineers from the University of Surrey have made a breakthrough in understanding how welded components behave inside the extreme conditions of a reactorâoffering critical insights for designing safer and longer-lasting fusion energy systems.
Working in collaboration with the UK Atomic Energy Authority (UKAEA), the National Physical Laboratory, and global supplier of scientific instruments for nanoengineering TESCAN, researchers have developed and used an advanced microscopic method to map hidden weaknesses locked inside welded metals during manufacturing that can compromise reactor components and reduce their lifespan.
The research, published in the Journal of Materials Research and Technology, details how they examined P91 steelâa very strong and heat-resistant metal candidate for future fusion plants. Researchers applied an advanced imaging technique using a plasma-focused ion beam and digital image correlation (PFIB-DIC) to map residual stress in ultra-narrow weld zones that were previously too small to study with conventional methods.
Crystalsâfrom sugar and table salt to snowflakes and diamondsâdonât always grow in a straightforward way. New York University researchers have captured this journey from amorphous blob to orderly structures in a new study published in Nature Communications.
In exploring how crystals form, the researchers also came across an unusual, rod-shaped crystal that hadnât been identified before, naming it âZangeniteâ for the NYU graduate student who discovered it.