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Physicist Dr. Lídia Del Rio, Essentia Foundation’s Research Fellow for Quantum Information Theory at the University of Zürich, explains to Hans Busstra one of the strangest quantum conundra confronting the foundations of physics: the Frauchiger-Renner (FR) thought experiment.

Scientific papers discussed in this video:

Quantum theory cannot consistently describe the use of itself.
Daniela Frauchiger & Renato Renner: https://www.nature.com/articles/s4146… experiments in a quantum computer, Nuriya Nurgalieva, Simon Mathis, Lídia del Rio, Renato Renner: https://arxiv.org/abs/2209.06236 Other interesting links related to the video: Quantum ‘thought experiment software’ https://github.com/XuemeiGu/Quanundrum Great Quantum artwork by Nuriya Nurgalieva: https://www.theoryverse.com/art Part One: Modelling Observers 00:00 Introduction 04:13 The object-subject divide in quantum mechanics 07:58 How would you explain the Wigner’s Friend thought experiment? 09:40 Observations are not facts 12:16 Is collapse relative? 14:11 Losing information = measurement 15:38 How do you model the agent in quantum mechanics? 17:54 What is reversibility in QM? Part Two: Explaining the Frauchiger-Renner Thought Experiment 22:14 Lídia explains Maxwell’s Demon and how the demon can be modelled 29:28 Formatting the ‘hard drive’ of the demon equals the energy gained 31:20 Lídia explains the Frauchiger-Renner thought experiment 41:51 The quantum circuit of the FR experiment 50:31 Where the experiment gets really weird 54:52 How to make sense of the weirdness? Part Three: The Implications and Meaning of the FR Experiment 1:03:59 What assumptions CANNOT all be true? 1:07:47 Critique from the physics community on the FR experiment 1:13:30 The philosophical implications of the FR experiment 1:16:04 Agreeing or disagreeing on Heisenberg cuts 1:17:27 Quanundrum software to test thought experiments 1:20:14 (No title – you might want to add something here) 1:23:16 Does the FR experiment “favor” a many-worlds interpretation, or does it require an epistemic approach? 1:25:04 Every theory, at some point, breaks 1:26:57 On the (in)completeness of quantum theory 1:29:35 What the FR experiment could mean for quantum computers… 1:32:06 What makes the FR experiment REALLY strange? 1:35:31 You cannot have an outside view AND know what’s going on inside… 1:36:01 What does it mean philosophically? 1:40:16 What if objective collapse or many-worlds is true? 1:43:20 Do you believe in free will? 1:45:54 Lídia does believe in an objective world… 1:47:15 What would a world weirder than quantum mechanics look like? 1:52:37 Where does thinking about “different” universes become relevant for physics? 1:55:51 On What the Bleep Do We Know, quantum woo, and the real meaning of quantum mechanics… 1:57:52 Nature doesn’t care about our Heisenberg cut… 1:59:33 Quantum mechanics and non-dualism 2:02:04 Physicists should be aware of their own faiths, religion, and mortality… 2:04:06 On the nature of the self, and how Lídia’s work has informed her outlook on life 2:09:31 Final words Sesame Street Russian Dolls video, under fair use: • Sesame Street Matryoshka Doll 10 All music licensed under Storyblocks and Soundstripe All stock footage licensed under Storyblocks Interview content copyright by Essentia Foundation, 2025 www.essentiafoundation.org.

Thought experiments in a quantum computer.
Nuriya Nurgalieva, Simon Mathis, Lídia del Rio, Renato Renner:
https://arxiv.org/abs/2209.

Other interesting links related to the video:

Quantum ‘thought experiment software’

That’s the question raised by physicist Dr. Richard Lieu at The University of Alabama in Huntsville. In a paper published in the Monthly Notices of the Royal Astronomical Society, Lieu offers a theory that could challenge one of the biggest assumptions in astrophysics. His idea: gravity can exist without any mass at all.

The study explores a different solution to the same equations that normally describe gravity—both in Newtonian theory and in general relativity. These equations link mass with the gravitational force it creates. Lieu focused on what’s known as the Poisson equation, a simplified form of Einstein’s field equations used for describing gravity in weaker fields, like those around galaxies.

This equation typically has one well-known solution: gravity that weakens with distance, created by mass. But there’s another, lesser-known solution that’s often ignored. It can also create an attractive force but doesn’t come from any actual matter.

There are two ways of dealing with this public health problem. One is to devise a comprehensive strategy to combat social inequality that will prevent disease before it happens. Another way is to develop a pill that treats the wear and tear of stress and toxins on the body.

Believe it or not, there are experiments on such pills underway.

Candidates include dasatinib, quercetin, metformin, rapamycin and fisetin among many others. These drugs may slow or even reverse aging in anyone, but they hold the greatest promise for improving America’s health because they disproportionately help the disadvantaged. This population bears the greatest burden of disease by far, so even small health gains in this population can go a long way.


Americans would much prefer a pill or a vaccine over a contentious policy battle.

Purpose of ReviewCerebral amyloid angiopathy (CAA) is a disease of the cerebral vasculature that can result in microhemorrhages, as well as intraparenchymal and subarachnoid hemorrhage, superficial siderosis (SS), and/or secondary infarct/inflammation…

Scientists are left baffled after NASA’s Perseverance rover discovered a bizarre rock on Mars.

The captured images show hundreds of millimetre-sized marbles packed together in an alien-like mass.

Unlike anything ever seen before, the marbles strikingly stand out in the rusty red dust that covers the Martian surface.

Global plastics production is concentrated in oil-producing countries with advanced petrochemical industries, while plastics disposal has shifted from landfill to incineration, with recycling consistently low, according to a global trade-linked material flow analysis of plastics for the year 2022.

Coronary Artery Disease (CAD) is the most common cardiovascular disease worldwide, threatening human health, quality of life and longevity. Aging is a dominant risk factor for CAD. This study aims to investigate the potential mechanisms of aging-related genes and CAD, and to make molecular drug predictions that will contribute to the diagnosis and treatment.

We downloaded the gene expression profile of circulating leukocytes in CAD patients (GSE12288) from Gene Expression Omnibus database, obtained differentially expressed aging genes through “limma” package and GenaCards database, and tested their biological functions. Further screening of aging related characteristic genes (ARCGs) using least absolute shrinkage and selection operator and random forest, generating nomogram charts and ROC curves for evaluating diagnostic efficacy. Immune cells were estimated by ssGSEA, and then combine ARCGs with immune cells and clinical indicators based on Pearson correlation analysis. Unsupervised cluster analysis was used to construct molecular clusters based on ARCGs and to assess functional characteristics between clusters. The DSigDB database was employed to explore the potential targeted drugs of ARCGs, and the molecular docking was carried out through Autodock Vina.