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Summary: Researchers used artificial intelligence to predict how enzymes interact with various substrates. The team developed an AI model that can accurately predict whether an enzyme can work with a particular molecule.

Their enzyme substrate prediction (ESP) model provides a valuable tool for drug research and biotechnology, with applications ranging from the creation of new drugs to the production of biofuels.

Lifespan by simply slowing the aging of an organ, such as the intestine? CNRS researchers have discovered how to extend the life expectancy of zebrafish by reactivating a gene within intestinal cells. The results were published in the journal Nature Aging on May 4, 2023.

The intestine plays a crucial role in an anti-aging approach as well as general health. Over a century ago, Elie Metchnikov observed that aging ensued from increased inflammation of the intestine and microbial infiltration within . The more we age, the less the serves as a barrier, allowing the undesirable particles and bacteria that cause the more rapid aging of the organism to pass through.

In a new study, Miguel Godinho Ferreira and his team at the Institute for Research on Cancer and Aging (Ircan) in Nice (CNRS/Inserm/Université Côte d’Azur) have studied the impact on aging of telomere length in the intestinal cells of zebrafish. As with humans, these chromosome extremities shrink faster in the than in other organs during the course of a life, which is why this process plays such an important role in aging.

A SpaceX Dragon capsule carrying four private astronauts arrived at the International Space Station early Monday (May 22) after a record-setting trip to the orbiting laboratory.

The Dragon spacecraft, named Freedom, launched atop a SpaceX Falcon 9 rocket on Sunday (May 21), kicking off the private Ax-2 mission to the orbiting lab for Axiom Space. It linked up with the station a day later at 9:12 a.m. EDT (1312 GMT) as both spacecraft sailed 262 miles above the Pacific Ocean, northeast of Japan.

Join us at 6:00 pm EST (11:00 pm UTC) for our Perpetual Life Hybrid Party live from our new location at 950 South Cypress Road in Pompano Beach, FL, & socialize with Immortalists from Around the World, hosted by hosted by Tonya Scholz & Rudi Hoffman.

Stay “In Zoom” for our 7:00 pm (12:00 am-midnight UTC) YouTube Streaming Service. This month, we are excited to have two speakers. First, Erik Nelson, Director of Clinical Programs at The Healthy Longevity Clinic, will present “Into the World of Longevity Medicine.”

Second, Bill Faloon: A founder of The Church of Perpetual Life and a leader in the Global Age Reversal movement, Bill will give a NEW Age Reversal Update at this service.

ChatGPT has changed the world since it emerged a few short months ago. Where will future advancements in generative AI take us?


Welcome back Katie Brenneman, a regular contributor to 21st Century Tech Blog. Several weeks ago when ChatGPT entered the headlines I suggested to Katie that she consider writing about Large Language Modelling (LLM) and the technological and societal implications in terms of its capabilities. Were we witnessing the birth of consciousness in this new artificial intelligence (AI) discipline, or were we coming to terms with what defines our sentience?

By definition, sentience is about feelings and sensations and not thinking. Consciousness, on the other hand, is about our awareness of self and our place in the world around us. And thinking is about the ability to reason, consider a problem, come up with an idea or solution, or have an opinion.

So from what we know about ChatGPT in its various iterations, does it meet the definition of any of these terms? Is it sentient? Is it conscious? Is it thinking?

Join top executives in San Francisco on July 11–12, to hear how leaders are integrating and optimizing AI investments for success. Learn More

When Microsoft-funded lab OpenAI launched ChatGPT in February, millions of people realized almost overnight what tech professionals have understood for a long time: Today’s AI tools are advanced enough to transform daily life as well as an incredibly broad range of industries. Microsoft’s Bing leaped from a distant second place in search to a much higher-profile level. Concepts like large language models (LLMs) and natural language processing are now part of mainstream discussion.

However, with the spotlight also comes scrutiny. Regulators around the world are taking note of AI’s risks to user privacy. The Elon Musk-backed Future of Life Institute amassed 1,000 signatures from tech leaders asking for a six-month pause on training AI tools that are more advanced than GPT-4, which powers ChatGPT.