Jimi Olaghere feels like he’s been reborn after a pioneering new treatment for sickle cell disease.
A researcher at the University of Houston College of Pharmacy is reporting an effective protocol for reprogramming human heart cells into specialized cells that conduct electricity throughout the heart to enable rhythmic heartbeat and repair diseased hearts. Bradley McConnell, professor of pharmacology, is the first to demonstrate the process and is reporting it in iScience.
It could be a massive breakthrough.
Currently, there are no treatments for cardiac cell death, the underlying basis of cardiovascular disease (CVD), which remains the leading cause of death globally. By 2035, CVD prevalence is expected to increase to 45.1% (more than 130 million people) in the U.S. while the financial cost is projected to increase by more than $131 million over the next two decades, reaching an astounding $1.1 trillion.
An international team of astrophysicists has made a puzzling discovery while analyzing certain star clusters. The University of Bonn played a major role in the study. The finding challenges Newton’s laws of gravity, the researchers write in their publication. Instead, the observations are consistent with the predictions of an alternative theory of gravity. However, this is controversial among experts. The results have now been published in the Monthly Notices of the Royal Astronomical Society.
In their work, the researchers investigated the so-called open star clusters. These are formed when thousands of stars are born within a short time in a huge gas cloud. As they “ignite,” the galactic newcomers blow away the remnants of the gas cloud. In the process, the cluster expands considerably. This creates a loose formation of several dozen to several thousand stars. The weak gravitational forces acting between them hold the cluster together.
“In most cases, open star clusters survive only a few hundred million years before they dissolve,” explains Prof. Dr. Pavel Kroupa of the Helmholtz Institute of Radiation and Nuclear Physics at the University of Bonn. In the process, they regularly lose stars, which accumulate in two so-called “tidal tails.” One of these tails is pulled behind the cluster as it travels through space. The other, in contrast, takes the lead like a spearhead.
Research in the field continues to focus on seizure prevention, prediction and treatment. Dr. Van Gompel predicts that the use of artificial intelligence and machine learning will help neurologists and neurosurgeons continue to move toward better treatment options and outcomes.
“I think we will continue to move more and more toward removing less and less brain,” says Dr. Van Gompel. “And in fact, I do believe in decades, we’ll understand stimulation enough that maybe we’ll never cut out brain again. Maybe we’ll be able to treat that misbehaving brain with electricity or something else. Maybe sometimes it’s drug delivery, directly into the area, that will rehabilitate that area to make it functional cortex again. That’s at least our hope.”
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What’s after 2024?
This work is public domain in support of the movement to abolish IP.
Continuous-time neural networks are one subset of machine learning systems capable of taking on representation learning for spatiotemporal decision-making tasks. Continuous differential equations are frequently used to depict these models (DEs). Numerical DE solvers, however, limit their expressive potential when used on computers. The scaling and understanding of many natural physical processes, like the dynamics of neural systems, have been severely hampered by this restriction.
Inspired by the brains of microscopic creatures, MIT researchers have developed “liquid” neural networks, a fluid, robust ML model that can learn and adapt to changing situations. These methods can be used in safety-critical tasks such as driving and flying.
However, as the number of neurons and synapses in the model grows, the underlying mathematics becomes more difficult to solve, and the processing cost of the model rises.
Greg Bear, the affable San Diego native who wrote such highly acclaimed and plausible science fiction novels as “Blood Music,” “Darwin’s Radio” and “Eon” and who helped create San Diego Comic-Con, died Saturday in Seattle. He was 71.
His books included “Blood Music” and “Darwin’s Radio,” which helped establish him as a “hard” sci-writer who created plausible tales with the help of scientists.
Continue reading “Greg Bear, prize-winning sci-fi author and Comic-Con co-founder, dies at 71” »
He has surpassed every medical expectation throughout his recovery. Gretarsson can now walk his dog, brush his teeth and give high-fives — as demonstrated when he met Iceland’s president.
“I have feelings in every finger, in the hand,” Gretarsson said recently alongside his wife, Silvia, Friday on “Good Morning Britain.”
Continue reading “I got world’s first double arm transplant — and can finally hug my grandkids” »
Former Neuralink president Max Hodak’s new BCI startup relies on photonics to send light through a patient’s optic nerve and transmit information.
b Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210,023, China.
c Institute of Chemical and Bioengineering, ETH Zurich, Vladimir Prelog Weg 1, 8093 Zurich, Switzerland.
Received 21st February 2019, Accepted 17th April 2019.
