Blog – Page 3237

In response to Bernardo Kastrup’s scathing criticisms of materialist explanations of the states of consciousness induced by psychedelics, David Nutt argues that we don’t need to adopt an untestable metaphysical worldview to explain the subjective richness of psychedelic experiences.In response to Bernardo Kastrup’s scathing criticisms of materialist explanations of the states of consciousness induced by psychedelics, David Nutt argues that we don’t need to adopt an untestable metaphysical worldview to explain the subjective richness of psychedelic experiences.

Let’s start with where we agree. It doesn’t make intuitive sense that alterations in (increased) complexity of brain waves could explain the whole range of subjective experiences that are reported under the influence of psychedelics. I agree they probably don’t in a direct sense — it seems to me much more likely that they are correlated because they both derive from a common change in another system or systems. Despite Bernardo’s criticisms and scepticism, I think we can plausibly develop theories as a result of neuroscience and neuroimaging research coupled with simultaneous acquisition of subjective effects that help explain the altered state of consciousness produced by psychedelics.

Where those might be is the question — and I will come back to it later — but at this point I think it is reasonable to suggest that the primary visual hallucinations (the Christmas tree lights) probably reflect a psychiatry-induced disruption of the layer 5 neurons in the visual cortex. This would degrade the ability of the complex cortical network that creates vision by integrating retinal inputs. Physiological studies of the neuronal workings of non-human visual systems predict that simple geometric shapes, colours and movement are the primary processes that are extracted from retinal inputs and from which more complex visual schema are then created. Psychedelics disrupt these higher-level constructions so allow the user to “see” the primary workings of the visual system that are not normally accessible to consciousness.

New research published in Scientific Reports suggests that breathing has a crucial role in coordinating brain activity in the prefrontal brain network during wakefulness. The findings provide new insights into the relationship between respiration and cognitive processing, and could have important implications for meditative practices that involve controlled breathing.

Previous studies have indicated that respiration can have significant effects on brain activity and cognitive processes. For example, changes in breathing patterns have been linked to alterations in attention, arousal, and emotional states. The respiratory system also shares neural pathways and connections with brain regions involved in cognition.

For their new study, the researchers focused on a specific structure called the nucleus reuniens (Reu), which acts as a link between the prefrontal cortex and the hippocampus. The researchers wanted to investigate how the synchronization of neural activity, particularly in the gamma rhythm frequency range, is organized in this network.