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The progress of a human being through life might be thought of as a mostly gradual succession of changes from the ovum to the grave.

But if you wake up one morning, look in the mirror, and wonder when you suddenly grew so much older, you may not be imagining things.

According to recent research into the molecular changes associated with aging, humans experience two drastic lurches forward, one at the average age of 44 and the other at the average age of 60.

Second, the crucial point is that there is no such thing as “natural resources.” That term implies that resources are already existing quantities that we merely have to pick up. In reality, resources are services that we derive by combining raw materials with knowledge and purpose. As Simon put it:

“…natural phenomena such as copper and oil and land were not resources until humans discovered their uses and found out how to extract and process them, and thereby made their services available to us. Hence resources are, in the most meaningful sense, created, and when this happens their availability increases and continues to increases as long as our knowledge of how to obtain them increases faster than our use of them, which is the history of all natural resources.” (p.75 footnote)

When people talk about what percentage of world resources are used up by the population of the USA they fail to recognize the creation of resources. Humans have become ever better at creating resources. Consider farmland. Farmland is not a natural resource. It requires tools and work by humans to produce what we want. And metals: Before we knew how to extract and use them, the vast amounts of tin, lead, iron, aluminum and other metals were not resources, they were merely materials. Neither oil nor gas nor petroleum were considered resources until humans saw how to use them to produce value and added our knowledge to turn minerals into resources.

Peggy Hoyt is a Florida-based estate planner and co-author, with Rudi Hoffman, of The Cryonics Estate Planning Handbook. We discuss dynastic trusts, the Rule Against Perpetuities and why it isn’t a problem in the USA, reasons to have a living will, how to build in financial incentives to revive you, the components of a cryonics/biostasis estate plan, the role of the trust protector, financing the preservation of pets, and more.

This study helps to close the gap involving cannabis and weight loss.


Can cannabidiol (CBD) or other cannabis-related products help with weight loss? This is what a recent study published in the journal Cannabis hopes to address as a researcher from NeX Therapeutics investigated how two phytocannabinoids, tetrahydrocannabivarin (THCV) and cannabidiol (CBD), could be used to manage weight loss. This study has the potential to help researchers, legislators, and the public better understand the benefits of cannabis for weight loss compared to prescription drugs currently on the market.

The study was conducted by Dr. Gregory Smith, who is the Founder, CEO, and Scientific Advisor of NeX Therapeutics, and involved 44 participants (31 women and 13 men) with an average age of 51.75. For the study, the participants used consumed mucoadhesive oral strips, which are drug delivery strips that adhere to the inside of the mouth, over 90 days. They were split into Group A, Group B, and Group P which involved single dose, double dose, and placebo, respectively, with one dose equaling 8 mg THCV/10 mg CBD. In the end, Dr. Smith made some interesting findings regarding how the strips helped manage weight loss.

According to the study, “The 16mg/20mg daily dose was superior for weight loss compared to the 8mg/10mg daily dose; both sets of results differed from placebo in a way that was statistically significant. The results of this study were congruent with the prior unpublished studies of a hemp extract containing significant percentages of THCV, CBDV and CBD.”

face_with_colon_three Year 2017 nad plus is essentially immortality of the colon which can reduce colon aging.


Boosting the level of a coenzyme regulating metabolism could help treat constipation and other aging-related intestinal problems. Researchers in Hangzhou, China, led by Qinsong Sheng from the First Affiliated Hospital of Zhejiang University and Zhenyu Ju from Hangzhou Normal University studied differences in colon function between young and old mice. They showed that older animals had more difficulty in defecation through the gastrointestinal tract and that this was associated with a lower level of the coenzyme nicotinamide adenine dinucleotide (NAD). Treatment with an NAD precursor improved defecation ability, whereas administering a drug that blocks NAD synthesis led to worsened colon function in mice. These findings point to NAD as a key regulator of colon motility and suggest a therapeutic strategy for older individuals with bowel-movement problems.

face_with_colon_three year 2024.


Genes from regenerative organisms rejuvenate intestinal stem cells in fruit flies.

In a groundbreaking experiment, Japanese researchers transferred regenerative genes to fruit flies, leading to improved intestinal health and enhanced stem cell activity. This discovery opens new possibilities for anti-aging strategies in higher organisms, including humans, through targeted gene therapy.

Researchers including those from the University of Tokyo’s Graduate School of Pharmaceutical Sciences transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

A battery that’s safer and cheaper than lithium-ion while offering comparable energy density? That sounds like a pipe dream. But such a battery is in fact in the works, using a chemistry of renewables to store over 220 Wh/kg. Singaporean startup Flint believes it has the formula for the most sustainable battery the world has ever seen, capable of replacing lithium for applications like EV power and grid storage. Maybe that is a dream. Or maybe it’s the revolutionary eco-optimized battery of the near-future.

A fully sustainable paper battery that can be recycled and dropped in compost at the end of its life cycle sounds too good to be true. It kicks off a major cynicism alert, and the questions flow like water through a burst dam.

Does it offer such low capacity as to be useless for anything outside a laboratory? No, Flint estimates energy density at 226 Wh/kg, which falls comfortably within the range of existing lithium tech.

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