The researchers identified a stress response that emerges from damaged mitochondria. By interrupting this stress response with a compound known as ISRIB, their results showed a marked improvement in blood sugar handling in mice.
A β-cell in the pancreas is responsible for releasing insulin, the hormone that regulates blood sugar.
These cells need high energy output from mitochondria to carry out their job. Weak energy conversion can disrupt insulin release, fueling the symptoms associated with type 2 diabetes.
On 23 June 2025, the world will get a look at the first images from one of the most powerful telescopes ever built: the Vera C. Rubin Observatory.
Perched high in the Chilean Andes, the observatory will take hundreds of images of the southern hemisphere sky, every night for 10 years. In doing so, it will create the most complete time-lapse record of our universe ever assembled. This scientific effort is known as the Legacy Survey of Space and Time (LSST).
Rather than focusing on small patches of sky, the Rubin Observatory will scan the entire visible southern sky every few nights. Scientists will use this rolling deep-sky snapshot to track supernovae (exploding stars), asteroids, black holes, and galaxies as they evolve and change in real time. This is astronomy not as a static snapshot, but as a cosmic story unfolding night by night.
The universe is full of spectacular and violent events, but few are more dramatic than a black hole tearing apart a star. Now, thanks to advanced computer simulations, scientists have gotten their closest look yet at what this cosmic catastrophe might actually look — and even sound — like.
A team of astronomers, led by theoretical astrophysicist Elias Most of the California Institute of Technology (Caltech), modeled the dramatic final milliseconds before a neutron star, the incredibly dense core left behind by a massive stellar explosion, is devoured by a black hole.
IN A NUTSHELL 🤖 Veho has partnered with RIVR to introduce wheeled-legged robots for parcel delivery in Austin, Texas. 🚀 The robots feature precision engineering and adaptive mobility to navigate complex urban environments. 🔗 This collaboration aims to enhance delivery efficiency while reducing physical strain on human drivers. 🌐 The initiative represents a major step
The entire field of mathematics summarised in a single map! This shows how pure mathematics and applied mathematics relate to each other and all of the sub-topics they are made from.
#mathematics #DomainOfScience.
If you would like to buy a poster of this map, they are available here: North America: https://store.dftba.com/products/map–… else: http://www.redbubble.com/people/domin… French version: https://www.redbubble.com/people/domi… Spanish Version: https://www.redbubble.com/people/domi… I have also made a version available for educational use which you can find here: https://www.flickr.com/photos/9586967… To err is to human, and I human a lot. I always try my best to be as correct as possible, but unfortunately I make mistakes. This is the errata where I correct my silly mistakes. My goal is to one day do a video with no errors! 1. The number one is not a prime number. The definition of a prime number is a number can be divided evenly only by 1, or itself. And it must be a whole number GREATER than 1. (This last bit is the bit I forgot). 2. In the trigonometry section I drew cos(theta) = opposite / adjacent. This is the kind of thing you learn in high school and guess what. I got it wrong! Dummy. It should be cos(theta) = adjacent / hypotenuse. 3. My drawing of dice is slightly wrong. Most dice have their opposite sides adding up to 7, so when I drew 3 and 4 next to each other that is incorrect. 4. I said that the Gödel Incompleteness Theorems implied that mathematics is made up by humans, but that is wrong, just ignore that statement. I have learned more about it now, here is a good video explaining it: • Gödel’s Incompleteness Theorem — Numberphile 5. In the animation about imaginary numbers I drew the real axis as vertical and the imaginary axis as horizontal which is opposite to the conventional way it is done. Thanks so much to my supporters on Patreon. I hope to make money from my videos one day, but I’m not there yet! If you enjoy my videos and would like to help me make more this is the best way and I appreciate it very much. / domainofscience Here are links to some of the sources I used in this video. Links: Summary of mathematics: https://en.wikipedia.org/wiki/Mathema… Earliest human counting: http://mathtimeline.weebly.com/early–… First use of zero: https://en.wikipedia.org/wiki/0#Historyhttp://www.livescience.com/27853-who–… First use of negative numbers: https://www.quora.com/Who-is-the-inve… Renaissance science: https://en.wikipedia.org/wiki/History… History of complex numbers: http://rossroessler.tripod.com/https://en.wikipedia.org/wiki/Mathema… Proof that pi is irrational: https://www.quora.com/How-do-you-prov… and https://en.wikipedia.org/wiki/Proof_t… Also, if you enjoyed this video, you will probably like my science books, available in all good books shops around the work and is printed in 16 languages. Links are below or just search for Professor Astro Cat. They are fun children’s books aimed at the age range 7–12. But they are also a hit with adults who want good explanations of science. The books have won awards and the app won a Webby. Frontiers of Space: http://nobrow.net/shop/professor-astr… Atomic Adventure: http://nobrow.net/shop/professor-astr… Intergalactic Activity Book: http://nobrow.net/shop/professor-astr… Solar System App: Find me on twitter, instagram, and my website: http://dominicwalliman.com / dominicwalliman / dominicwalliman / dominicwalliman. Everywhere else: http://www.redbubble.com/people/domin… French version: https://www.redbubble.com/people/domi… Spanish Version: https://www.redbubble.com/people/domi…
To err is to human, and I human a lot. I always try my best to be as correct as possible, but unfortunately I make mistakes. This is the errata where I correct my silly mistakes. My goal is to one day do a video with no errors!
1. The number one is not a prime number. The definition of a prime number is a number can be divided evenly only by 1, or itself. And it must be a whole number GREATER than 1. (This last bit is the bit I forgot).
A team of chemists at the University of Cambridge has developed a powerful new method for adding single carbon atoms to molecules more easily, offering a simple one-step approach that could accelerate drug discovery and the design of complex chemical products.
The research, recently published in the journal Nature under the title “One-carbon homologation of alkenes,” unveils a breakthrough method for extending molecular chains—one carbon atom at a time. This technique targets alkenes, a common class of molecules characterized by a double bond between two carbon atoms. Alkenes are found in a wide range of everyday products, from anti-malarial medicines like quinine to agrochemicals and fragrances.
Led by Dr. Marcus Grocott and Professor Matthew Gaunt from the Yusuf Hamied Department of Chemistry at the University of Cambridge, the work replaces traditional multi-step procedures with a single-pot reaction that is compatible with a wide range of molecules.
The reliable manipulation of the speed at which light travels through objects could have valuable implications for the development of various advanced technologies, including high-speed communication systems and quantum information processing devices. Conventional methods for manipulating the speed of light, such as techniques leveraging so-called electromagnetically induced transparency (EIT) effects, work by utilizing quantum interference effects in a medium, which can make it transparent to light beams and slow the speed of light through it.
Despite their advantages, these techniques only enable the reciprocal control of group velocity (i.e., the speed at which the envelope of a wave packet travels through a medium), meaning that a light beam will behave the same irrespective of the direction it is traveling in while passing through a device. Yet the nonreciprocal control of light speed could be equally valuable, particularly for the development of advanced devices that can benefit from allowing signals to travel in desired directions at the desired speed.
Researchers at the University of Manitoba in Canada and Lanzhou University in China recently demonstrated the nonreciprocal control of the speed of light using a cavity magnonics device, a system that couples microwave photons (i.e., quanta of microwave light) with magnons (i.e., quanta of the oscillations of electron spins in materials).
