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Asking AI to act like an expert can make it less reliable

To get the best out of AI, some users tell it to provide answers as if it were an expert. Others ask it to adopt a persona, such as a safety monitor, to guide its responses. However, this approach can sometimes hurt performance, according to a study available on the arXiv preprint server.

To see how well large language models (LLMs) behave when they are told to be someone else, researchers from the University of California ran a huge test using 12 different personas across six language models. These included experts in fields like math, coding and STEM (science, technology, engineering and mathematics) as well as general roles such as creative writer or safety monitor.

The team found that adopting a persona was something of a double-edged sword. While it makes AI sound more professional and keeps it safer (more likely to follow rules and less likely to generate harmful content), it sometimes performs worse at recalling facts.

Thousands of websites are accidentally broadcasting sensitive data, study finds

Researchers have discovered a major security leak hiding in plain sight on the internet that could expose the personal data and financial records of millions of people. In a paper published on the arXiv preprint server, Nurullah Demir of Stanford University and colleagues analyzed 10 million websites to see how often API (application programming interfaces) credentials are exposed. These are digital keys or tokens that enable different software programs to communicate and are often used to process bank payments and access cloud storage.

The team used a huge database called the HTTP Archive, which tracks how millions of real websites work. They looked at live, running versions of sites to monitor how data is processed as pages load.

By examining the websites while they were active, the researchers identified API credentials that appear only when a user visits a site. These credentials are specific strings of text that a website uses to identify itself to services like banks or cloud providers.

Dust-resilient perovskite solar cells could cut manufacturing costs and expand green energy worldwide

Research appearing in Communications Materials has shown that perovskite solar cells (PSCs) are remarkably resilient to dust during production, challenging the industry belief that high-performance solar technology must be manufactured in sterile and expensive cleanrooms. This discovery could reduce the need for ultra-clean factories, making solar cell production cheaper and more accessible worldwide.

PSCs are a new type of technology that uses a unique crystal structure to harvest light. They are thinner, lighter, and potentially much cheaper to produce than the traditional silicon panels found on roofs today. However, traditional silicon cells are incredibly fragile during the making process; even a single microscopic dust particle can ruin a cell. This forces manufacturers to use expensive, energy-hungry cleanrooms, creating a massive barrier to production in developing nations.

Researchers at Swansea University’s Faculty of Science & Engineering have now found that perovskite technology has a unique tolerance to common dust and debris.

Why no individual is like another when epigenetics come into play

Why do animals behave differently, and what are the consequences of this? A research team from the Collaborative Research Center NC³ at Bielefeld University and the University of Münster now provides a new explanation: epigenetic processes—chemical markings on DNA—may play a key role. The study, published in the journal Trends in Ecology & Evolution, links individuality, environmental adaptation, genetics, ecology, and evolution in a novel way.

“With our study, we propose that individuality and epigenetic variation influence each other,” explains Dr. Denis Meuthen, an evolutionary biologist at Bielefeld University, who is one of the study’s main authors. “This bidirectionality—this mutual interaction—helps us to better understand ecological and evolutionary processes.”

Laser-modified graphene enables molecule-thick films to grow only where needed

Researchers from the University of Jyväskylä and Aalto University have developed a new method based on laser modification, which allows metal-organic materials to be grown locally one molecule-thick layer at a time. The method enables the precise construction of films of different shapes and offers new ways to modify the properties of materials for various applications. The study was published in the journal ACS Nano.

Atomic layer deposition (ALD) is a method used especially in the semiconductor industry to produce high-quality thin films with atomic layer accuracy. The method was developed in the 1970s by the Finnish Tuomo Suntola, and it has since become an important technology.

In ALD, thin films are grown one atomic layer at a time through controlled chemical reactions between the reactants, as well as their interactions with the surface. This so-called bottom-up method allows for precise film thickness adjustment.

Unusual signal may prove existence of primordial black holes

It may well take years to prove, but a pair of University of Miami astrophysicists could be on the verge of a cosmic breakthrough that will confirm the existence of primordial black holes and the role they play in one of cosmology’s greatest mysteries.

Believed to have formed within the first fraction of a second after the Big Bang, primordial black holes are purely theoretical. But if confirmed, these hypothetical cosmic phenomena, which could range from asteroid-sized to massive, could explain a lot, including the nature of dark matter—the invisible substance that constitutes about 85% of all matter in the universe, acting as “gravitational glue” that holds galaxies together.

“We believe our study will aid in confirming that they actually do exist,” Nico Cappelluti, an associate professor in the College of Arts and Sciences’ Department of Physics, said of the research he and Ph.D. student Alberto Magaraggia have conducted.

Motivations behind violent extremism uncovered in new global study

New research from the University of St Andrews has revealed that human readiness for intergroup violence is not a single or unified mindset. Published in the Proceedings of the National Academy of Sciences, the new study, spanning 58 countries and involving more than 100 researchers from various institutions around the world, demonstrates that violent extremist intentions are driven by two fundamentally different psychological motivations.

These are defensive extremism, which aims to protect a group from perceived threats, and offensive extremism, which seeks to establish group dominance and expand influence.

This preregistered study analyzed data from 18,128 participants globally. The findings indicate that defensive extremist intentions are consistently more prevalent, showing higher levels of endorsement than offensive intentions in 56 out of the 58 surveyed nations. This suggests a widespread tendency to find protective violence more morally acceptable than violence aimed at conquest.

RNA-guided CRISPR system activates gene expression

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA. The research includes two complementary studies, one examining the biological function of the system and the other revealing the molecular mechanism that enables it.

The team’s research on a variant of the CRISPR—Clustered Regularly Interspaced Short Palindromic Repeats—system broadens understanding of CRISPR’s natural diversity and provides a foundation for new gene-regulation technologies. Because this CRISPR variant activates genes without cutting DNA, it could be adapted for precise gene control applications, including research tools and potential therapeutic strategies that turn on genes without permanently altering the genome.

One study shows that this CRISPR system, using a strand of RNA as a guide, finds specific sections of DNA, known as genes, and attracts the cell’s own gene expression machinery to the location to activate the gene. The second study explains how the molecular complex performs this task, revealing how its structure allows it to recruit RNA polymerase—the enzyme responsible for transcribing DNA into RNA—to initiate gene expression.

Topological solitons power a chip-scale frequency comb source

Caltech scientists have developed a new way to produce optical frequency combs—important tools in devices that keep time and measure distances very precisely—at the chip scale, an advance that should make it easier to incorporate such combs in optical devices and more practical to use them outside the laboratory.

To generate the combs, the new research demonstrates the utility of a robust class of light pulses, called topological solitons, that had been previously predicted but largely unexplored until now. The scientists, led by Caltech’s Alireza Marandi, professor of electrical engineering and applied physics, describe their findings in a paper published in Nature.

Frequency combs are light sources that emit a precise ruler-like “comb” of many evenly spaced frequencies. Over the last three decades, they have become important tools in spectroscopy, in telecommunications, and even in astronomical research. Currently, most frequency comb sources rely on bulky tabletop laser sources. The new work shows that an electrically pumped laser diode integrated with a photonic chip with strong nonlinearity can serve as a frequency comb source.

Protein modification discovery opens cancer therapy possibilities

A research team led by Purdue University’s W. Andy Tao has discovered a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive energy processes. Their discovery, published in Nature Chemistry, opens a new route to therapeutic cancer intervention.

“Mutation is considered the driving mechanism leading to cancer. Many mutations are hidden and harmless, but the mutation of enzymes like kinases can lead to the uncontrolled growth of cancer cells,” said Tao, a professor of biochemistry in Purdue’s College of Agriculture.

The study wades into the interactive dynamic complexity of the human genome (containing 20,000 to 25,000 genes) and the human proteome (containing more than 1 million proteins). The researchers identified a new modification on proteins because of the mutation in the isocitrate dehydrogenase (IDH) enzyme, which affects how kinase enzymes control protein function.

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