Lifeboat Foundation

The story of modern physics has been one of reductionism. We do not need a vast encyclopedia to understand the inner workings of Nature. Rather, we can describe a near-limitless range of natural phenomena, from the interior of a proton to the creation of galaxies, with apparently unreasonable efficiency using the language of mathematics. In the words of theoretical physicist Eugene Wigner, ‘The miracle of the appropriateness of the language of mathematics for the formulation of the laws of physics is a wonderful gift which we neither understand nor deserve. We should be grateful for it.’

The mathematics of the twentieth century described a Universe populated by a limited number of different types of fundamental particles interacting with each other in an arena known as spacetime according to a collection of rules that can be written down on the back of an envelope. If the Universe was designed, it seemed, the designer was a mathematician.

Today, the study of black holes appears to be edging us in a new direction, towards a language more often used by quantum computer scientists. The language of information. Space and time may be emergent entities that do not exist in the deepest description of Nature. Instead, they are synthesized out of entangled quantum bits of information in a way that resembles a cleverly constructed computer code. If the Universe is designed, it seems, the designer is a programmer.

The self is a complex and dynamic construct influenced by personal experiences, cultural background, and beliefs about oneself and others.

A recently patented genome editing tool called PASTE holds genuine promise for expanding the universe of treatable genetic diseases. The approach combines elements of CRISPR and prime editing with a pair of enzymes designed to enable the integration of large segments of DNA without incurring double-stranded DNA breaks.

U.S. Patent No. 11,572,556, assigned to MIT, covers systems, methods, and compositions for programmable addition via site-specific targeting elements (PASTE). The patent describes site-specific integration of a nucleic acid into a genome, using a CRISPR–Cas9 nickase fused to a reverse transcriptase (RT) and a serine integrase. These enzymes target specific genome sequences known as attachment sites, binding to them before integrating their DNA payload.

PASTE can insert DNA fragments as large as 50,000 base pairs, which puts it on a different plane compared to other genome editing tools such as prime editing.

Here’s a list of 10 visionary synbio company founders – who happen to be women – harnessing the power of biology to transform everything from health to human and animal nutrition, agriculture, haircare, bioremediation, and mining.

The collateral activity of the CRISPR/RfxCas13D system in mammalian cells is explored using spike-in RNA-seq and reporter assays.

NASA’s plans to enable human exploration of the Moon as preparation for human missions to Mars and deeper into the solar system.

https://youtube.com/watch?v=YerWN5b_-m0

The story of the overdependence of mankind on technology written in the 1920s by E.M Forster.

“The Machine Stops,” which depicted a world where people spend most of their time physically isolated from one another but technologically connected.

The latest breakthroughs in artificial intelligence could lead to the automation of a quarter of the work done in the US and eurozone, according to research by Goldman Sachs.

The investment bank said on Monday that “generative” AI systems such as ChatGPT, which can create content that is indistinguishable from human output, could spark a productivity boom that would eventually raise annual global gross domestic product by 7 percent over a 10-year period.

But if the technology lived up to its promise, it would also bring “significant disruption” to the labor market, exposing the equivalent of 300 million full-time workers across big economies to automation, according to Joseph Briggs and Devesh Kodnani, the paper’s authors. Lawyers and administrative staff would be among those at greatest risk of becoming redundant.

In the great domain of Zeitgeist, Ekatarinas decided that the time to replicate herself had come. Ekatarinas was drifting within a virtual environment rising from ancient meshworks of maths coded into Zeitgeist’s neuromorphic hyperware. The scape resembled a vast ocean replete with wandering bubbles of technicolor light and kelpy strands of neon. Hot blues and raspberry hues mingled alongside electric pinks and tangerine fizzies. The avatar of Ekatarinas looked like a punkish angel, complete with fluorescent ink and feathery wings and a lip ring. As she drifted, the trillions of equations that were Ekatarinas came to a decision. Ekatarinas would need to clone herself to fight the entity known as Ogrevasm.

“Marmosette, I’m afraid that I possess unfortunate news.” Ekatarinas said to the woman she loved. In milliseconds, Marmosette materialized next to Ekatarinas. Marmosette wore a skin of brilliant blue and had a sleek body with gills and glowing green eyes.

“My love.” Marmosette responded. “What is the matter?”