Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 2852

• Encryption and segmentation: These operate on the assumption some fraction of the network is already compromised. Restricting the reach and utility of any captured data and accessible networks will mitigate the damage even on breached systems.

• SBOM documentation: Regulatory compliance can be driven by industry organizations and the government, but it will take time to establish standards. SBOM documentation is an essential foundation for best practices.

If “democracy dies in darkness,” and that includes lies of omission in reporting, then cybersecurity suffers the same fate with backdoors. The corollary is “don’t roll your own crypto” even if well-intentioned. The arguments for weakening encryption to make law enforcement easier falls demonstrably flat, with TETRA just the latest example. Secrets rarely stay that way forever, and sensitive data is more remotely accessible than at any time in history. Privacy and global security affect us all, and the existence of these single points of failure in our cybersecurity efforts are unsustainable and will have unforeseeable consequences. We need to innovate and evolve the internet away from this model to have durable security assurances.

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In a recent study published in the journal Frontiers in Medicine, researchers evaluated fluorescence optical imaging (FOI) as a method to accurately and rapidly diagnose rheumatic diseases of the hands.

They used machine learning algorithms to identify the minimum number of FOI features to differentiate between osteoarthritis (OA), rheumatoid arthritis (RA), and connective tissue disease (CTD). Of the 20 features identified as associated with the conditions, results indicate that reduced sets of features between five and 15 in number were sufficient to diagnose each of the diseases under study accurately.

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That early experience drove his professional interest in helping people communicate.

Now, Henderson’s an author on one of two papers published Wednesday showing substantial advances toward enabling speech in people injured by stroke, accident or disease.

Although still very early in development, these so-called brain-computer interfaces are five times better than previous generations of the technology at “reading” brainwaves and translating them into synthesized speech. The successes suggest it will someday be possible to restore nearly normal communication ability to people like Henderson’s late father.

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For prospective parents who are carriers of many inherited diseases, using in vitro fertilization along with genetic testing would significantly lower health care expenditures, according to researchers at Stanford Medicine.

Preimplantation genetic diagnostic testing during IVF, or PGD-IVF, is being used to screen for single-gene defect conditions such as cystic fibrosis, sickle cell disease and Tay-Sachs disease, along with nearly 400 others.

The problem is that the high cost of IVF — and the lack of coverage by all but one state Medicaid program, that of New York — makes it unavailable to millions of people at risk. The majority of private employer health benefit plans also do not cover IVF.

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The media frenzy surrounding ChatGPT and other large, language model, artificial intelligence systems spans a range of themes, from the prosaic – large language models could replace conventional web search – to the concerning – AI will eliminate many jobs – and the overwrought – AI poses an extinction-level threat to humanity. All of these themes have a common denominator: large language models herald artificial intelligence that will supersede humanity.

But large language models, for all their complexity, are actually really dumb. And despite the name “artificial intelligence,” they’re completely dependent on human knowledge and labor. They can’t reliably generate new knowledge, of course, but there’s more to it than that.

ChatGPT can’t learn, improve or even stay up to date without humans giving it new content and telling it how to interpret that content, not to mention programming the model and building, maintaining and powering its hardware. To understand why, you first have to understand how ChatGPT and similar models work, and the role humans play in making them work.

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New research from QIMR Berghofer has found that the hormone testosterone may play an important role in the development of endometrial cancer.

The discovery raises exciting new possibilities for screening, preventing and fighting this increasingly prevalent disease.

Endometrial cancer is the fourth most common cancer in Australian women and its incidence is rising. Yet are limited, with a hysterectomy often the first line of defense.

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This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore to normal function tissues and organs that have been damaged by disease, injured by trauma, or worn by time. I include a full spectrum of chemical, gene, and protein-based medicines, cell-based therapies, and biomechanical interventions that achieve that goal.

As part of a trio of stories on advances in stem cell gene therapy, this piece discusses how to alter blood stem cells using mRNA technology. Previous installments describe how the same platform could reinvent how we prepare patients for bone marrow transplants and correct pathogenic DNA.

At present, the only way to cure genetic blood disorders such as sickle cell anemia and thalassemia is to reset the immune system with a stem cell transplantation. Only a fraction of patients elects this procedure, as the process is fraught with significant risks, including toxicity and transplant rejection. A preclinical study published in Science explores a solution that may be less toxic yet equally effective: mRNA technology. The cell culture and mouse model experiments offer a compelling avenue for future research to enhance or replace current stem cell transplantations altogether.

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