Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 269

📝 — Kee, et al.

This review focuses on compartmentalized inflammation in Multiple sclerosis (MS) and in particular, what we know about meningeal tertiary lymphoid structures which are organised clusters of immune cells, associated with more severe and progressive forms of MS.

Full text is available 👇

Multiple sclerosis (MS) is a chronic, immune-mediated, demyelinating disease of the central nervous system (CNS). The most common form of MS is a relapsing–remitting disease characterised by acute episodes of demyelination associated with the breakdown of the blood–brain barrier (BBB). In the relapsing–remitting phase there is often relative recovery (remission) from relapses characterised clinically by complete or partial resolution of neurological symptoms. In the later and progressive stages of the disease process, accrual of neurological disability occurs in a pathological process independent of acute episodes of demyelination and is accompanied by a trapped or compartmentalised inflammatory response, most notable in the connective tissue spaces of the vasculature and leptomeninges occurring behind an intact BBB.

Continue reading “A Review of Compartmentalised Inflammation and Tertiary Lymphoid Structures in the Pathophysiology of Multiple Sclerosis” | >

This presents another challenge: convincing patients to allow the use of their data. Some 70% of Americans have expressed concerns about data privacy, with 56% admitting they find AI in healthcare “scary.”

It isn’t helped by the growing number of data breaches in the healthcare space, with 88 million patients having had their personal health information compromised in data breaches last year alone. Undoubtedly, if AI-powered healthcare is to maintain its trajectory, the sector will need to address these cybersecurity concerns.

AI is no longer a prospect but a reality today. It’s already being deployed in doctors’ offices and hospitals to analyze patient data, handle back-office tasks and assist surgeons. Anticipated to decrease administrative costs by up to 30%, free up hundreds of thousands of hours of physicians’ time and cut surgical waiting times—for the millions of Americans currently suffering in silence, whether due to affordability or accessibility, AI will offer a lifeline.

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For years, they had been losing their central vision—what allows people to see letters, faces, and details clearly. The light-receiving cells in their eyes had been deteriorating, gradually blurring their sight.

But after receiving an experimental eye implant as part of a clinical trial, some study participants can now see well enough to read from a book, play cards, and fill in a crossword puzzle despite being legally blind. Science Corporation, the California-based brain-computer interface company developing the implant, announced the preliminary results this week.

When Max Hodak, CEO of Science and former president of Neuralink, first saw a video of a blind patient reading while using the implant, he was stunned. It led his company, which he founded in 2021 after leaving Neuralink, to acquire the technology from Pixium Vision earlier this year.

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Glass might soon have some competition from an unlikely rival – bamboo. Scientists in China have turned regular old bamboo into a transparent material that’s also resistant to fire and water, and suppresses smoke.

Silica glass, made from sand, is still the go-to building material when you need something transparent but strong, like windows. But it’s not particularly sustainable, and can be heavy and brittle.

Transparent wood has actually been muscling in on glass’s turf for a few years now. Scientists chemically remove the lignin from the wood fibers, then treat the remaining material with plexiglass or epoxy. The end result is a material that’s transparent, renewable, and as strong as or stronger than glass, while being lighter and a better thermal insulator.

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By November 2024, 15 U.S. states had established regulations on ghost guns, though exact requirements vary. The rules typically require a serial number, background checks for firearm component purchases and reporting to authorities that a person is producing 3D-printed guns.

For instance, in New Jersey, a 2019 law mandates that all ghost guns have a serial number and be registered. Under current New York law, possession or distribution of a 3D-printed gun is classified as a misdemeanor. However, a proposed law seeks to elevate the manufacturing of firearms using 3D-printing technology to a felony offense.

As technology advances and rules evolve, criminals who use 3D-printed firearms will continue to pose threats to public safety and security, and governments will continue playing catch-up to effectively regulate these weapons.

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We named him Squirt—not because he was the smallest of the 16 cuttlefish in the pool, but because anyone with the audacity to scoop him into a separate tank to study him was likely to get soaked. Squirt had notoriously accurate aim.

As a comparative psychologist, I’m used to assaults from my experimental subjects. I’ve been stung by bees, pinched by crayfish and battered by indignant pigeons. But, somehow, with Squirt it felt different. As he eyed us with his W-shaped pupils, he seemed clearly to be plotting against us.

Of course, I’m being anthropomorphic. Science does not yet have the tools to confirm whether cuttlefish have emotional states, or whether they are capable of conscious experience, much less sinister plots. But there’s undeniably something special about cephalopods—the class of ocean-dwelling invertebrates that includes cuttlefish, squid and octopus.

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