Lifeboat Foundation: Safeguarding Humanity
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Tunneling is a fundamental process in quantum mechanics, involving the ability of a wave packet to cross an energy barrier that would be impossible to overcome by classical means. At the atomic level, this tunneling phenomenon significantly influences molecular biology. It aids in speeding up enzyme reactions, causes spontaneous DNA mutations, and initiates the sequences of events that lead to the sense of smell.

Photoelectron tunneling is a key process in light-induced chemical reactions, charge and energy transfer, and radiation emission. The size of optoelectronic chips and other devices has been close to the sub-nanometer atomic scale, and the quantum tunneling effects between different channels would be significantly enhanced.

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“Where are we going? Life, the timeless, mysterious gift, is still evolving. What wonders, or terrors, does evolution hold in store for us in the next ten thousand years? In a million? In six million? Perhaps the answer lies in this old house in this old and misty valley…” A benign and brilliant scientist (Edward Mulhare) discovers a way to accelerate human evolution. David McCallum (super-agent Illya Kuryakin from “The Man From Uncle”) plays the bitter young coal miner who is miraculously transformed into the man of the future. As a result of the experiment, the size of his brain grows grotesquely, a “sixth finger” appears, and he becomes the possessor of tremendous mental powers!

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Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved by the FDA to treat sickle cell disease in December 2023. That therapy is based on a highly studied system known as the CRISPR-Cas9 genetic scissor.

However, a newer and unique platform with the potential to make large-sized DNA removals, called Type I CRISPR or CRISPR-Cas3, waits in the wings for potential therapeutic use.

A new study from Yan Zhang, Ph.D., Assistant Professor in the Department of Biological Chemistry at the University of Michigan Medical School, and her collaborators at Cornell University develops off-switches useful for improving the safety of the Type I-C/Cas3 gene editor. The study, “Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for 3 Genome Editing Applications,” is published in the journal Molecular Cell.

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Already, the graphene efforts have offered “a breath of fresh air” to the community, Alicea says. “It’s one of the most promising avenues that I’ve seen in a while.” Since leaving Microsoft, Zaletel has shifted his focus to graphene. “It’s clear that this is just where you should do it now,” he says.

But not everyone believes they will have enough control over the free-moving quasiparticles in the graphene system to scale up to an array of qubits—or that they can create big enough gaps to keep out intruders. Manipulating the quarter-charge quasiparticles in graphene is much more complicated than moving the Majoranas at the ends of nanowires, Kouwenhoven says. “It’s super interesting for physics, but for a quantum computer I don’t see it.”

Just across the parking lot from Station Q’s new office, a third kind of Majorana hunt is underway. In an unassuming black building branded Google AI Quantum, past the company rock-climbing wall and surfboard rack, a dozen or so proto–quantum computers dangle from workstations, hidden inside their chandelier-like cooling systems. Their chips contain arrays of dozens of qubits based on a more conventional technology: tiny loops of superconducting wires through which current oscillates between two electrical states. These qubits, like other standard approaches, are beset with errors, but Google researchers are hoping they can marry the Majorana’s innate error protection to their quantum chip.

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