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Jun 21, 2023

Extreme DNA resolution: Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds

Posted by in categories: biotech/medical, genetics, nanotechnology

Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current. Scientists can determine DNA’s sequence of nucleotides—which encodes genetic information—by analyzing how each one perturbs this current as it passes through. The research has been published in Nature Nanotechnology.

Currently, the passage of molecules through a and the timing of their analysis are influenced by random physical forces, and the rapid movement of molecules makes achieving high analytical accuracy challenging. Radenovic has previously addressed these issues with optical tweezers and viscous liquids. Now, a collaboration with Georg Fantner and his team in the Laboratory for Bio-and Nano-Instrumentation at EPFL has yielded the advancement she’s been looking for—with results that could go far beyond DNA.

Continue reading “Extreme DNA resolution: Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds” »

Jun 21, 2023

Billionaire businessman who traveled to space with Jeff Bezos’s Blue Origin among group missing on Titanic submarine voyage

Posted by in categories: business, space travel

The Titan sub, which is carrying five passengers, is thought to have no more than four days’ worth of emergency oxygen on board.

Jun 21, 2023

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Posted by in category: biotech/medical

Dr David Sünderhauf.

Study removes AMR plasmids using a mobile, broad-host-range CRISPR-Cas9 delivery tool.

Jun 21, 2023

Less-invasive cardiac MRI helps in early evaluation of patients: Study

Posted by in category: biotech/medical

An estimated 3 million people with severe chest discomfort and slightly increased troponin levels visit emergency rooms each year. When the heart muscle suffers damage due to a heart attack, high amounts of protein troponin are produced. It is still unknown how to diagnose and treat people with chest discomfort with detectable or barely increased troponin.

Now, a new study from researchers at Wake Forest University School of Medicine reveals that cardiac magnetic resonance imaging (MRI), is a safe and valuable tool to help evaluate these complex patients.

The study findings appear online today in Circulation: Cardiovascular Imaging, a journal of the American Heart Association.

Jun 21, 2023

AI 100: The most promising artificial intelligence startups of 2023

Posted by in categories: climatology, cyborgs, robotics/AI, sustainability

CB Insights has unveiled the winners of the seventh annual AI 100 — a list of the 100 most promising private AI companies across the globe.

Around one-third of this year’s winners are focused on AI applications across specific industries — such as visual dubbing for the media & entertainment sector or textile recycling for fashion & retail. A total of 40 vendors are focused on cross-industry solutions, like AI assistants & human-machine interfaces (HMIs), digital twins, climate tech, and smell tech.

Additionally, 27 companies in this cohort are developing tools like vector database tech and synthetic datasets to support AI development.

Jun 21, 2023

How North Korea Built the World’s Largest Criminal Empire

Posted by in categories: economics, existential risks

Have you ever wondered how can North Korea afford its nuclear program and the luxury goods for its leadership when its economy is effectively cut off from the world? Well… let me tell you a little secret.

If you want to support the channel, check out my Patreon: https://www.patreon.com/ExplainedWithDom.

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Jun 20, 2023

New study predicts the masses of the largest supermassive black holes in the universe

Posted by in category: cosmology

Near the center of the Milky Way Galaxy sits an immense object that astronomers call Sagittarius A*. This “supermassive” black hole may have grown in tandem with our galaxy, and it’s not alone. Scientists suspect that similar behemoths lurk at the heart of almost all large galaxies in the cosmos.

Some can get really big, said Joseph Simon, postdoctoral researcher in the Department of Astrophysical and Planetary Science at the University of Colorado Boulder.

“The black hole at the center of our galaxy is millions of times the mass of the sun, but we also see others that we think are billions of times the ,” he said.

Jun 20, 2023

Laryngeal cancer: What you should know

Posted by in category: biotech/medical

We spoke with head and neck surgeon Eduardo Diaz Jr., M.D., to learn more about laryngeal cancer.

How common is laryngeal cancer?

It’s much less common than it used to be because fewer Americans are smoking, which is a risk factor for this type of cancer. That said, laryngeal cancers represent about one-fifth of head and neck cancers.

Jun 20, 2023

Brightest Cosmic Explosion of All Time: Scientists May Have Solved the Mystery of Its Persistence

Posted by in categories: energy, space

This quickly turned out to be a record-setter. It was dubbed the Brightest Of All Time, or the “Boat,” as convenient shorthand among astronomers studying and observing the event. Not only did the Boat start out bright, it refused to fade away like other bursts.

We still do not fully know why the burst was so exceptionally bright, but our new study, published in Science Advances, provides an answer for its stubborn persistence.

Continue reading “Brightest Cosmic Explosion of All Time: Scientists May Have Solved the Mystery of Its Persistence” »

Jun 20, 2023

Meta announces new AI model that can replicate the voices of loved ones, but says it’s too risky to release

Posted by in category: robotics/AI

“There are many exciting use cases for generative speech models, but because of the potential risks of misuse, we are not making the Voicebox model or code publicly available at this time,” the company said in a research post. “While we believe it is important to be open with the AI community and to share our research to advance the state of the art in AI, it’s also necessary to strike the right balance between openness with responsibility.”

Representatives for Meta did not immediately respond to Insider’s request for comment, made outside normal working hours.

Meta said in the news release that the model could allow visually impaired people to hear messages from friends in their voices or allow users to speak in foreign languages in their own voice. The company also said the tech opened up the possibility for creators to edit audio tracks for video or create more natural-sounding voices for virtual assistants.