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A pair of studies from the laboratory of Evangelos Kiskinis, Ph.D., associate professor in the Ken and Ruth Davee Department of Neurology’s Division of Neuromuscular Disease and of Neuroscience, have uncovered novel cellular mechanisms that are involved in two types of genetic amyotrophic lateral sclerosis, or ALS.

The findings, published in Science Advances and Cell Reports, improve the understanding of ALS, a progressive neurodegenerative disease that attacks in the brain and , and provides support for the future development of targeted therapies.

An estimated 32,000 individuals are currently living with ALS in the U.S., according to the Les Turner ALS Foundation. There are two types of ALS: sporadic (non-genetic), which makes up more than 90% of all ALS cases, and familial (genetic).

Barbara Corcoran almost missed out on “the best hire” she ever made — all because the prospective employee seemed too introverted.

“When I started my business [in 1973], I needed people to join my real estate company,” the millionaire investor and real estate entrepreneur said in a recent TikTok video. “But I had little to offer, and good people were really hard to get.”

In walked Esther Kaplan, who would eventually become Corcoran’s business partner and longtime president of The Corcoran Group. But at the time, Kaplan didn’t seem like the right fit for the sales position she’d applied for, Corcoran said.

An international team of astrophysicists including Princeton’s Andy Goulding has discovered the most distant supermassive black hole ever found, using two NASA space telescopes: the Chandra X-ray Observatory (Chandra) and the James Webb Space Telescope (JWST).

The black hole, which is an estimated 10 to 100 million times more massive than our sun, is 13.2 billion light-years away in the galaxy UHZ-1, which means the telescopes are peering back in time to when the universe was “extremely young,” Goulding said — only about 450 million years old.

“This is one of the most dramatic discoveries to come out of the James Webb Space Telescope” and the discovery of the most distant growing supermassive black hole known, said Michael Strauss, professor and chair of astrophysical sciences at Princeton, who discussed the findings with the researchers but was not part of the research team. “Indeed, it completely smashes the old record.”

Tesla has signed a deal with the EG Group, a massive gas station and convenience store operator, to sell its Supercharger hardware to be deployed as an EG-branded product.

It’s the second of such deals that Tesla has made in just a few weeks.

Last month, Tesla surprised many when it announced it reached a deal with BP to sell them $100 million worth of Supercharger hardware to be deployed at BP gas stations across the US under the BP brand.