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Life Science Animation presents a groundbreaking 2D video animation that delves into the world of peptide-based cancer immunotherapies. In collaboration with Micropep, we explore Enterome’s OncoMimics platform, a novel approach to activating pre-existing memory T cell immunity for a more robust anti-tumor response.

Current immunotherapies often fall short as they only stimulate naïve T cell responses, leading to limited efficacy. Enterome’s innovative solution utilizes bacterial peptides, known as OncoMimics, that mimic tumor antigens. These OncoMimics are derived from common microbiome bacteria and are naturally tolerated by the human body.

In this video, we illustrate how OncoMimics cross the gut barrier, activating memory T cells and leading to a rapid and potent proliferation. The result? A targeted attack on tumor cells, leading to their destruction. Enterome’s OncoMimics are currently in human clinical development for the treatment of both solid and liquid tumors.

At Life Science Animation, we specialize in creating video animations that help explain complex scientific concepts, including those in biotech and aG tech. Our animations make science accessible and engaging for all audiences.

Continue reading “Revolutionizing Cancer Treatment with Enterome’s OncoMimics: A 2D Animation” | >

Similar to human teenagers, teenage galaxies are awkward, experience growth spurts and enjoy heavy metal — nickel, that is.

A Northwestern University-led team of astrophysicists has just analyzed the first results from the CECILIA (Chemical Evolution Constrained using Ionized Lines in Interstellar Aurorae) Survey, a program that uses NASA’s James Webb Space Telescope (JWST) to study the chemistry of distant galaxies.

According to the early results, so-called “teenage galaxies” — which formed two-to-three billion years after the Big Bang — are unusually hot and contain unexpected elements, like nickel, which are notoriously difficult to observe.

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Science: Research suggest that dinosaurs 🦕 🦖 may have influenced how humans age today.

Human aging may have been influenced by millions of years of dinosaur domination according to a new theory from a leading aging expert. The ‘longevity bottleneck’ hypothesis has been proposed by Professor Joao Pedro de Magalhaes from the University of Birmingham in a new study published in BioEssays. The hypothesis connects the role that dinosaurs played over 100 million years with the aging process in mammals.

While some reptiles and amphibians show no significant signs of aging, all mammals—including humans—show a marked .

Professor de Magalhaes’ hypothesis suggests that during the Mesozoic Era, mammals faced persistent pressure for rapid reproduction during the reign of dinosaurs, which over 100 million years led to the loss or inactivation of genes associated with , such as processes associated with tissue regeneration and DNA repair.

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In a new study using brain scans of former NFL athletes, Johns Hopkins Medicine researchers say they found high levels of a repair protein present long after a traumatic brain injury such as a concussion takes place. The repair protein, known as 18 kDa translocator protein (TSPO), is known to be present in the brain at high levels in the immediate aftermath of brain injury as part of the inflammatory response and to facilitate repair. The new findings, published Oct. 30 in JAMA Network Open, suggest that brain injury and repair processes persist for years after players end collision sports careers, and lead to long-term cognitive problems such as memory loss.

“The findings show that participating in repeated collision sports like football may have a direct link to long-term inflammation in the brain,” says Jennifer Coughlin, M.D., associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. Ongoing studies like the current one, she says, add details about how the brain heals — or doesn’t — and how repeated brain injuries, even mild ones that players routinely shake off, may over time affect cognitive abilities.

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Learn more about Clinical Trials and Immunotherapy for Head and Neck Cancer. Featuring speakers: Dan Paul Zandberg, MD (Director, Head and Neck and Thyroid Cancer Disease Sections, Division of Hematology and Oncology, UPMC Hillman Cancer Center), Ricardo Zwirtes, MD (VP, Clinical Development, SQZ Biotechnologies), Jeffery Shoop (Two-Time Head and Neck Cancer Survivor. (Presented by SQZ Biotechnologies, SPOHNC and Head and Neck Cancer Alliance)

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