Lifeboat Foundation

The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage.

Researchers around the world are seeking to identify techniques that use nanoparticles in the treatment of disease. Such particles are about 100 nanometers—one thousandth of a millimeter—in diameter, and within them researchers are inserting large numbers of even smaller drug molecules.

Optimism for this approach in the treatment of various forms of cancer has been particularly great.

Why does all of this matter? The unfortunate truth is that each of us will experience plenty of mental pain, misery, and frustration in our lifetimes. Mistaking the voice in our head for a thing and labeling it “me” brings us into conflict with the neuropsychological evidence that shows there is no such thing. This mistake — this illusory sense of self — is the primary cause of our mental suffering. When you can’t sleep at night, is it because you are worried about a stranger’s problems, or is it your problems that keep you up? For most of us, we worry about my work problems, my money problems, and my relationship problems. What would happen if we removed the “self” from these problems?

I am distinguishing mental suffering from physical pain. Pain occurs in the body and is a physical reaction—like when you stub your toe or break an arm. The suffering I speak of occurs in the mind only and describes things such as worry, anger, anxiety, regret, jealousy, shame, and a host of other negative mental states. I know it’s a big claim to say that all these kinds of suffering are the result of a fictitious sense of self. For now, the essence of this idea is captured brilliantly by Taoist philosopher and author Wei Wu Wei when he writes, “Why are you unhappy? Because 99.9 percent of everything you think, and of everything you do, is for yourself — and there isn’t one.”

Multiple sclerosis (MS) affects roughly 2.5 million people worldwide and is a neurological disease affecting the brain and spinal cord. More specifically, MS is when the immune system attacks the body’s protective layer around nerve fibers known as myelin sheaths. The breakdown of myelin sheath leads to a disconnect between your brain and body. The immune cells responsible for myelin sheath deterioration include CD4+ T cells, or effector cells, which are part of the body’s first line of defense. In MS, the effector cells do not recognize that the myelin sheath is a normal part of the body. Therefore, the effector cells become the dominant cell type, trying to kill and get rid of the myelin sheath. The immune response will generate inflammation which destroys the myelin sheath leading to a disruption of signals along the nerves from the brain to the body.

A group of researchers at Johns Hopkins University School of Medicine recently published a therapy that controls the symptoms of MS. The goal of the therapy was to stop effector cells from attacking the myelin sheath and to promote the production of T regulatory cells-or T regs-which have been demonstrated to reduce autoimmune effects.

Dr. Giorgio Raimondi, PhD, MSc, Jordan Green, and others used three therapeutic agents to control MS symptoms. Researchers used microparticles, which are small, bioengineered spheres to deliver the agents. The first agent is a combination of two proteins which include Interleukin-2 (IL2) and an antibody that promotes T reg production. IL2 stimulates T cell expansion, while the antibody blocks specific parts of IL2 to specifically expand T regs compared to effector cells. The second agent includes a molecule that presents a protein specific to myelin so that the immune response will generate T regs specifically designed to protect the myelin sheath. Finally, the third agent is rapamycin, which is an immunosuppressant drug designed to reduce effector T cells.

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Government can give Universal basic income to everyone.

https://www.msn.com/en-us/money/other/the-a-i-endgame-is-tha…st-says/vi

Ben Goertzel, CEO of decentralized artificial intelligence marketplace SingularityNET, says “there are far more rewarding things for humans beings to do than [scrambling] around to get resources.”

Continue reading “The A.I. endgame is that no humans need to work for a living, cognitive scientist says” »

Today, we explore a timelapse of the future, specifically future technology. How will technology look 1,000 years from now? In the world today, many technologies are accelerating exponentially. Humans are discovering things that would mystify scientists even a few decades ago, but our progress resembles a blip in the grand scale of our technological evolution over the next millennium.

Sources:
https://pastebin.com/raw/1vAehwKn.

Continue reading “Timelapse of Future Technology: Next 1000 Years” »

A groundbreaking study conducted by researchers from the Duke-National University of Singapore (Duke-NUS) Medical School has shown promising results in repairing damaged heart muscle by transplanting precursor stem cells into pigs.

The research, which focuses on regenerating heart tissue damaged by a lack of oxygen, could revolutionize the treatment of heart failure in humans, a report shared by NewAtlas tells us.

The characteristics of the “egress complex” found in termite mounds can be replicated to enhance the optimize interior climate of buildings.

Of the approximately 2,000 recognized termite species.

A species is a group of living organisms that share a set of common characteristics and are able to breed and produce fertile offspring. The concept of a species is important in biology as it is used to classify and organize the diversity of life. There are different ways to define a species, but the most widely accepted one is the biological species concept, which defines a species as a group of organisms that can interbreed and produce viable offspring in nature. This definition is widely used in evolutionary biology and ecology to identify and classify living organisms.

Year 2014 😗😁

We propose PolyRef, a method for a polymorphic defense to defeat automated attacks on web applications. Many websites are vulnerable to automated attacks. Basic anti-automation countermeasures such as Turing tests provide minimal efficacy and negatively impact the usability and the accessibility of the protected application. Motivated by the observation that many automated attacks rely on interaction with the publicly visible code transmitted to the browser, PolyRef proposes to make critical elements of the underlying webpage code polymorphic, rendering machine automation impractical to implement. We categorize the threats that rely on automation and the available anti-automation approaches. We present two techniques for using polymorphism as an anti-automation defense.