Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 2290

Scientists have made a pivotal advancement in creating compact laser technology using organic semiconductors. This development promises diverse applications, from enhancing OLED displays to aiding in disease detection and environmental monitoring. The new laser, which emits green light in short pulses, overcomes the traditional need for an external laser in organic semiconductor lasers. Credit: SciTechDaily.com.

Scientists have achieved a breakthrough in creating an electrically driven organic semiconductor laser, paving the way for advanced and versatile laser applications.

Researchers at the University of St. Andrews are leading a significant breakthrough in a decades-long challenge to develop compact laser technology.

Read more | >

New research has unveiled an advancement in Light Detection and Ranging (LIDAR) technology, offering unparalleled sensitivity and precision in measuring the distance of remote objects.

This research, published in Physical Review Letters, is a result of a collaboration between the group of Professor Yoon-Ho Kim at POSTECH in South Korea, and the Quantum Science and Technology Hub at the University of Portsmouth.

Coherent LIDAR has long been a cornerstone in distance measurement, but its capabilities have been restrained by the time of the light source. In a pioneering move, researchers have introduced two-photon LIDAR, eliminating the range limitations imposed by coherence time, to achieve accurate and precise ranging of a remote object situated far beyond the coherence time dictated by the spectral bandwidth of the light source.

Read more | >

The advancement of higher cognitive abilities in humans is predominantly associated with the growth of the neocortex, a brain area key to conscious thinking, movement, and sensory perception. Researchers are increasingly realizing, however, that the “little brain” or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans, explains Prof. Henrik Kaessmann from the Center for Molecular Biology of Heidelberg University.

His research team has – together with Prof. Dr Stefan Pfister from the Hopp Children’s Cancer Center Heidelberg – generated comprehensive genetic maps of the development of cells in the cerebella of humans, mice, and opossums. Comparisons of these data reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development spanning over 160 million years of mammalian evolution.

Read more | >

Genome and Structure:

HIV’s genome is a 9.7 kb linear positive-sense ssRNA.1 There is a m7G-cap (specifically the standard eukaryotic m7GpppG as added by the host’s enzymes) at the 5’ end of the genome and a poly-A tail at the 3’ end of the genome.2 The genome also has a 5’-LTR and 3’-LTR (long terminal repeats) that aid its integration into the host genome after reverse transcription, that facilitate HIV genetic regulation, and that play a variety of other important functional roles. In particular, it should be noted that the integrated 5’UTR contains the HIV promoter called U3.3,4

HIV’s genome translates three polyproteins (as well as several accessory proteins). The Gag polyprotein contains the HIV structural proteins. The Gag-Pol polyprotein contains (within its Pol component) the enzymes viral protease, reverse transcriptase, and integrase. The Gag-Pol polyprotein is produced via a −1 ribosomal frameshift at the end of Gag translation. Because of the lower efficiency of this frameshift, Gag-Pol is synthesized 20-fold less frequently than Gag.5 The frameshift’s mechanism depends upon a slippery heptanucleotide sequence UUUUUUA and a downstream RNA secondary structure called the frameshift stimulatory signal (FSS).6 This FSS controls the efficiency of the frameshift process.

Read more | >