Lifeboat Foundation: Safeguarding Humanity
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A recent study by European scientists shows that highly sensitive sensors based on color centers in a diamond can be used to record electrical activity from neurons in living brain tissue. The work is published in the journal Scientific Reports.

Before people encounter symptoms of diseases such as dementia, slight changes have usually occurred already in the . It may be that parts of the brain are swelling up or clumps of proteins are forming. These small changes might influence how in the brain signal each other and communicate, how information is processed and memorized.

Medical scientists want to study these minor changes that occur in the very early stages of a disease. That way, the intention is to learn more about the causes of the disease to provide new insights and more efficient treatments. Today, microscopic studies on the brain are performed with one of two strategies: Optical inspection of brain tissue samples from animals or deceased patients that suffer from the studied disease or measurements of the signals from the nerve cells using wires, coloring, or light.

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Physicists at RIKEN have developed an electronic device that hosts unusual states of matter, which could one day be useful for quantum computation.

When a material exists as an ultrathin layer—a mere one or a few atoms thick—it has totally different properties from thicker samples of the same material. That’s because confining electrons to a 2D plane gives rise to exotic states. Because of their flat dimensions and their broad compatibility with existing semiconductor technologies, such 2D materials are promising for harnessing new phenomenon in .

These states include quantum spin Hall insulators, which conduct electricity along their edges but are electrically insulating in their interiors. Such systems when coupled with superconductivity have been proposed as a route toward engineering topological superconducting states that have potential application in future topological quantum computers.

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In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams at the University of Würzburg have identified new details in this process.

As complicated as their name is, they are important for the human organism in the fight against pathogens and cancer: Vγ9Vδ2 T cells are part of the immune system and, as a subgroup of white blood cells, fight cells and cells infected with pathogens. They recognize their potential victims by their altered cell metabolism.

Research teams from the University of Würzburg and the University Hospital of Würzburg, together with groups in Hamburg, Freiburg, Great Britain and the U.S., have now gained new insights into how these cells manage to look inside the cell. Thomas Herrmann, Professor of Immunogenetics at the Institute of Virology and Immunobiology and his colleague Dr. Mohindar Karunakaran at Julius-Maximilians-Universität Würzburg (JMU), were responsible for the study published in the journal Nature Communications.

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Rotor Technologies is now in production on a full-size unmanned helicopter for civilian use. Based on the Robinson R44 Raven II, the R550X flies for more than three hours, at speeds up to 150 mph (241 km/h), carrying up to 1,200 lb (550 kg) of cargo.

According to Torklaw, helicopters have about 9.84 crashes per 100,000 hours of flight time. That’s curiously low, given their reputation and the fact that “general aircraft” have 7.28 crashes per 100,000 hours. But still, they’re notoriously tricky to fly, and there are a growing number of projects attempting to make them much easier, using simple fly-by wire joystick controls, or even simpler one-finger tablet control schemes.

Safest of all, of course, is to leave the humans on the ground altogether, and that’s what New Hampshire company Rotor Technologies has been focused on from its modest hangar at Nashua Airport, about 30 miles (50 km) outside Boston. It’s been flying two R22-based autonomous chopper prototypes since December last year, across nine locations in New Hampshire, Idaho and Oregon. It wrapped up its test campaign in November, having logged “more than 20 hours” of flight time.

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The negative side of not having it on a disk or flash drive.

Sony announced on Monday that it would remove all Discovery content, including shows like “MythBusters” and “Deadliest Catch,” from user libraries, even if they had been purchased on the PlayStation Store.

The company, which owns and operates PlayStation game consoles, said in a brief statement that the Discovery shows would be deleted on Dec. 31, attributing the decision to “our content licensing arrangements with content providers.”

The move came as Warner Bros. Discovery, which owns Discovery content, is seeking to add more subscribers to its Max and Discovery+ streaming services, in competition with others like Netflix and Disney+.

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One of the focus areas at Together Research is new architectures for long context, improved training, and inference performance over the Transformer architecture. Spinning out of a research program from our team and academic collaborators, with roots in signal processing-inspired sequence models, we are excited to introduce the StripedHyena models. This release includes StripedHyena-Hessian-7B (SH 7B), a base model, and StripedHyena-Nous-7B (SH-N 7B), a chat model. StripedHyena builds on the many lessons learned in the past year on designing efficient sequence modeling architectures: H3, Hyena, HyenaDNA, and Monarch Mixer.

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While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins.

A team of researchers led by the University of Massachusetts Amherst leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.

The research, published in the journal Molecular Cell, explores members of a family of proteins called serpins, which are implicated in a number of diseases. The research is the first to investigate how the location and composition of carbohydrates attached to the serpins ensure that they fold correctly.

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