Lifeboat Foundation

An advanced biosensor brain–computer interface is bringing thought-controlled robots a step closer to reality.

Hack your way out of the wrong reality.

Today, at the Moriond conference, the ATLAS and CMS collaborations have both presented the observation of a very rare process: the simultaneous production of four top quarks. They were observed using data from collisions during Run 2 of the Large Hadron Collider (LHC).

Both experiments’ results pass the required five-sigma statistical significance to count as an observation—ATLAS’s observation with 6.1 sigma, higher than the expected significance of 4.3 sigma, and CMS’s observation with 5.5 sigma, higher than the expected 4.9 sigma —making them the first observations of this process.

The top quark is the heaviest particle in the Standard Model, meaning it is the particle with the strongest ties to the Higgs boson. This makes top quarks ideal for looking for signs of physics beyond the Standard Model.

Hailey-Hailey disease is a rare, inherited condition characterized by patches of blisters appearing mainly in the skin folds of the arm pits, groin and under the breasts. It is caused by a mutation in the gene that codes for a specific protein involved in the transportation of calcium and manganese ions from the cell cytoplasm and into a sac-like organelle called the Golgi apparatus.

Scientists at Tohoku University, together with colleagues in Japan, have uncovered some aspects of this protein’s structure that could help researchers understand how it works. The findings, published in the journal Science Advances, help build the foundations for research into finding treatments for Hailey-Hailey disease and other neurodegenerative conditions.

The protein the team studied is called secretory pathway Ca²⁺/Mn²⁺-ATPase, or SPCA for short. It is located in the Golgi apparatus, a cellular sac-like structure that plays a crucial role in protein quality control before they are released into cells. The Golgi apparatus also acts like a sort of calcium ion storage container. Calcium ions are vital for cell signaling processes and are important for proteins to function properly, so maintaining the right calcium ion balance inside cells is necessary for their day-to-day activities.

A team of chemists and computer scientists from the Swiss Federal Institute of Technology Lausanne, the University of California and Institut des Sciences et Ingenierie Chimiques, Ecole, have developed an ecosystem of tools to boost machine-learning-based design of metal-organic frameworks.

In their study, reported in the journal ACS Central Science, Kevin Maik Jablonka, Andrew Rosen, Aditi Krishnapriyan and Berend Smit coded tools to convert data into machine learning inputs to create a system to boost machine-learning frameworks.

Reticular chemistry is the science of designing and synthesizing porous crystalline materials with certain predefined structures and properties (building blocks). These materials, known as metal-organic frameworks (MOFs) have applications in gas storage, separation, catalysis, sensing and drug delivery.

A team of Rutgers University scientists dedicated to pinpointing the primordial origins of metabolism – a set of core chemical reactions that first powered life on Earth – has identified part of a protein that could provide scientists clues to detecting planets on the verge of producing life.

The research, published on March 10 in the journal Science Advances.

<em>Science Advances</em> is a peer-reviewed, open-access scientific journal that is published by the American Association for the Advancement of Science (AAAS). It was launched in 2015 and covers a wide range of topics in the natural sciences, including biology, chemistry, earth and environmental sciences, materials science, and physics.

Genetic Engineering extends far beyond the controversial news headlines that obsess over ‘designer babies’. In the science community, gene-editing tools like CRISPR and PRIME editing will do nothing less than save the planet.

The Rise Of Genetic Engineering (2022)
Writers: Kyle McCabe, Christopher Webb Young.
Stars: Rodolphe Barrangou, George Church, Mary Beth Dallas.
Genre: Documentary.
Country: United States.
Language: English.
Release Date: August 24, 2022 (United States)

Continue reading “The Rise Of Genetic Engineering | Gene-Editing | Documentary” »

A semirigid stamp and a standard photolithography mask-aligner enable a reliable and scalable pickup and release process for van der Waals materials integration at the wafer scale.

Harvard Medical School professor Michael E. Greenberg has won The 2023 Brain Prize for his decades-long research on brain plasticity, alongside University of Cambridge professor Christine E. Holt and Max Planck Institute Director Erin M. Schuman.