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Adults with a diagnosis of carpal tunnel syndrome are 39% more likely to develop HF during 10 years of follow-up, especially amyloidosis, compared with those without a carpal tunnel syndrome diagnosis, researchers reported.

“The increased rate of HF among patients with carpal tunnel syndrome requires attention because HF is a common disease associated with high mortality,” Mark Luedde, MD, from Christian-Albrechts-University of Kiel and Cardiology Joint Practice in Bremerhaven, Germany, and colleagues wrote in JAMA Network Open. “Early diagnosis of HF is a key to successful treatment, particularly for [transthyretin] cardiac amyloidosis, which has been associated with carpal tunnel syndrome in a recent study.”

In a retrospective study, Luedde and colleagues analyzed data from 81,898 adults from 1,284 general practices in Germany with an initial diagnosis of carpal tunnel syndrome from 2005 to 2020, using the Disease Analyzer database. The mean age of patients was 53 years and 66.7% were women. Researchers used propensity-score matching to match patients without carpal tunnel syndrome to those with carpal tunnel syndrome. The main outcome was the initial diagnosis of HF up to 10 years after the index date of carpal tunnel syndrome diagnosis. As a negative control, researchers analyzed the association of carpal tunnel syndrome with cancer.

Researchers led by Leipzig University have found a application in oncology for the scientific field of Physics of Cancer. This is a milestone for the new research field, proving its clinical relevance for the first time. Based on tissue and cell mechanics and using machine learning, the team developed a marker for cancer cell motility in digital pathology.

The marker delivers new information about breast tumors that will improve the ability to predict the risk of metastasis, even after a decade has passed. The researchers have just published their new findings in the journal Physical Review X.

In a retrospective study of 1,380 female breast cancer patients, conducted in close collaboration with Professor Axel Niendorf from the Pathologie Hamburg-West institute, doctoral researcher Pablo Gottheil from the research group led by Professor Josef Alfons Käs at Leipzig University found that a collective transition of cancer cells to motility, known in specialist circles as “unjamming,” significantly increases the risk of distant metastases.

Breast milk is not simply sustenance. It also is rich in micronutrients that are critical for healthy brain development in infants.

Now, researchers have identified a component of breast milk that promotes how neurons form connections in infants’ brains. Myo-inositol is a small cyclic sugar molecule in breast milk that also is found in a typical adult diet, including in fruits and grains. The study emphasizes the powerful role that what we eat plays in brain function. It was published in PNAS on July 11.

“The effects of micronutrients on the brain are really under-appreciated,” says Thomas Biederer, Ph.D., associate professor of neurology and principal investigator. “As a neuroscientist, our findings were stunning to me.”

Lymphoma is often thought of as a cancer of lymph nodes, but it’s actually a cancer of the lymphocytes. Lymphocytes are white blood cells that manage inflammation in the body.

Chronic inflammation can sometimes lead to a lymphoma known as marginal zone lymphoma.

Marginal zone lymphoma is a rare, slow-growing B-cell lymphoma. Because it’s so rare, marginal zone lymphoma is often treated like other subtypes of B-cell lymphomas, and new treatment options are often explored through clinical trials that group marginal zone lymphoma with other B-cell lymphoma subtypes.

Mozilla Firefox has finally added support for NVIDIA’s upscale technology for video content known as the RTX Video Super Resolution (VSR).

Patreon: https://www.patreon.com/seanmcarroll.
Blog post with audio player, show notes, and transcript: https://www.preposterousuniverse.com/podcast/2022/06/06/200-…ultiverse/

The 200th episode of Mindscape! Thanks to everyone for sticking around for this long. To celebrate, a solo episode discussing a set of issues naturally arising at the intersection of philosophy and physics: how to think about probabilities and expectations in a multiverse. Here I am more about explaining the issues than offering correct answers, although I try to do a bit of that as well.

Continue reading “Mindscape 200 | Solo: The Philosophy of the Multiverse” »

As we continue the search for evidence of dark energy, one scientist proposes a radical new idea about what’s going on in the cosmos.

Summary: A new study reveals that individuals with stronger ‘mindreading’ abilities, or the capacity to understand others’ feelings and intentions, are more successful in cooperative tasks. This trait, also known as ‘theory of mind,’ is not directly tied to intelligence and can potentially be improved through training programs.

The research demonstrated that those with high theory of mind were more effective in cooperation, particularly when paired with individuals with similar abilities. The study underlines the potential to foster enhanced cooperation in various settings like schools, workplaces, or colleges by improving these abilities.

In this talk we introduce Shivon Zilis, Project Director at Neuralink, to her team’s work and the ethical impacts of implanting technology into the brain. We learn about the latest developments in Neuralink’s technology and the goals the team keeps in mind when designing and implementing technology that could change the way humans interact and understand technology.

Visit https://cucai.ca/ to learn more.

Continue reading “The Future of Brain Machine Interfaces — Shivon Zilis, Project Director at Neuralink | CUCAI 2021” »