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Most cancers are thought to evade the immune system. These cancers don’t carry very many mutations, and they aren’t infiltrated by cancer-fighting immune cells. Scientists call these cancers immunologically “cold.”

Now new research suggests such cancers aren’t as “cold” as once thought. Researchers from the La Jolla Institute for Immunology (LJI), UC San Diego Moores Cancer Center, and UC San Diego, have found that patients with “cold” tumors actually do make cancer-fighting T cells.

This discovery opens the door to developing vaccines or therapies to increase T cell numbers and treat many more types of cancer than currently thought possible.

Researchers at the University of Colorado Anschutz Medical Campus studying interactions between nerves and tumor microenvironments have found that commonly used drugs like botox may stop or slow the progression of certain head and neck cancers.

The study, published online today in the journal Med, examined how nerves within the tumor environment impact the immune system and cancer growth.

“We have long known that the intensity of nerve interactions within the are associated with worse outcomes in head and neck squamous cell carcinoma,” said the study’s lead author Laurel Darragh, an MD/Ph. D. student focused on radiation oncology at the University of Colorado School of Medicine. “This prompted us to investigate how these nerve interactions impact the adaptive immune system and tumor growth.”

Eyes with lower pigment (blue or grey eyes) don’t need to absorb as much light as brown or dark eyes before this information reaches the retinal cells. This might provide light-eyed people with some resilience to SAD.


Other theories propose it happens due to an imbalance in serotonin and melatonin in the body. Serotonin makes us feel energetic, while the release of melatonin makes us feel sleepy. Since melatonin is made from serotonin, people with SAD may potentially produce too much melatonin during the winter months, leaving them feeling lethargic or down.

All these studies are inconsistent and, in some cases, contradictory. But because SAD is likely due to a combination of many biological and physiological factors working together, these different explanations for what causes SAD may well be interconnected.

We have uncovered evidence that a person’s eye colour can have a direct effect on how susceptible they are to SAD.

The “Beneficial AGI Summit & Unconference” is a new event organized by SingularityNet and TrueAGI in collaboration with others. The Millennium Project is one of the sponsors of the event and our Jerome Glenn, Executive Director and co-founder of The Millennium Project, and José Cordeiro, MP Board member and RIBER and Venezuela Nodes Chair, are members of the organizing committee of the event. The Beneficial AGI summit will take place both online and physically and c/o Hilton Panama in Panama City. The streaming is free, get your ticket.

The objective of the conference is to bring together the leading voices in AI in actions to catalyze the emergence of beneficial AGI. Key themes of the event are: Constitution & Governance Framework, Global Brain Collective, Simulation / Gaming Environments, Scenarios analysis process, Potential scenarios (from 1 to 7).

On the first two days of the BGI Summit, Feb. 27–28, top thought leaders from around the globe will engage in comprehensive, detailed discussions of a wide range of questions regarding various approaches to AGI and their ethical, economic, psychological, political, environmental and other implications. The focus will be on discussing issues, making conceptual progress, forming collaborations, and engaging in the practical actions aimed at catalyzing the emergence of beneficial AGI based on the ideas and connections set in motion by all involved.

In a new study, scientists have mapped magnetic fields in galaxy clusters, revealing the impact of galactic mergers on magnetic-field structures and challenging previous assumptions about the efficiency of turbulent dynamo processes in the amplification of these fields.

Galaxy clusters are large, gravitationally bound systems containing numerous galaxies, hot gas, and dark matter. They represent some of the most massive structures in the universe. These clusters can consist of hundreds to thousands of galaxies, bound together by gravity, and are embedded in vast halos of hot gas called the intracluster medium (ICM).

ICM, consisting mainly of ionized hydrogen and helium, is held together by the gravitational pull of the cluster itself. Magnetic fields in large-scale structures, like galaxy clusters, play pivotal roles in shaping astrophysical processes. They influence the ICM, impact galaxy formation and evolution, contribute to cosmic ray transport, participate in cosmic magnetization, and serve as tracers of large-scale structure evolution.