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A new multi-platform ransomware-as-a-service (RaaS) operation named VanHelsing has emerged, targeting Windows, Linux, BSD, ARM, and ESXi systems.

VanHelsing was first promoted on underground cybercrime platforms on March 7, offering experienced affiliates a free pass to join while mandating a deposit of $5,000 from less experienced threat actors.

The new ransomware operation was first documented by CYFIRMA late last week, while Check Point Research performed a more in-depth analysis published yesterday.

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a transgene—that is, a gene that has been artificially inserted into an organism—into cynomolgus monkeys, which is a species of primate closely related to humans. The paper is published in the journal Nature Communications.

Small animal models such as mice do not fully replicate the complexity of human diseases, particularly in areas like infectious disease and neuropsychiatric disorders. This limitation has made non-human primates an essential model for .

However, genetic modification of these primates has been challenging. For example, conventional virus-based methods require specialized containment facilities and are limited in terms of the size of transgenes that the viruses can carry. Also, these methods do not allow for precise selection of modified embryos before implantation.

A couple weeks ago, I participated in the Mercor x Etched x Cognition Hackathon. The theme of the hackathon was “inference-time compute”— and this is what I worked on for 24 hours, with some added rigor, visualizations, and analysis.

You can view the original work here and the code here — my contribution is the hallucinations section for both.

Thanks to Allison Lim and Vijay Kumaravelrajan (alphabetical order) for helping me edit this!

This nonrandomized clinical trial reports outcomes for children with low-risk relapsed Hodgkin lymphoma treated with second-line chemotherapy and involved-field radiotherapy without autologous stem cell transplant.

A joint team of professors—Hajun Kim, Taejoon Kwon, and Joo Hun Kang—from the Department of Biomedical Engineering at UNIST has unveiled a novel diagnostic technique that utilizes artificially designed polymers known as peptide nucleic acid (PNA) as probes. The research is published in the journal Biosensors and Bioelectronics.

The fluorescence in situ hybridization (FISH) technique works by detecting fluorescent signals generated when probe molecules bind to specific genetic sequences in bacteria. This innovative FISH method employs two PNA molecules simultaneously. By analyzing the of 20,000 bacterial species, the research team designed PNA sequences that specifically target the ribosomal RNA of particular species.

The method is significantly faster and more accurate than traditional bacterial culture and (PCR) analysis, and it holds promise for reducing mortality rates in critical conditions such as sepsis, where timely administration of antibiotics is crucial.

Description: The American College of Physicians (ACP) developed this guideline based on the best available evidence on the comparative benefits and harms of pharmacologic treatments of acute episodic migraine headache, patients’ values and preferences, and economic evidence about these pharmacologic treatments. Methods: This guideline is based on a systematic review and network meta-analysis of the comparative benefits and harms of pharmacologic treatments of acute episodic migraine headaches, as well as systematic reviews of patients’ values and preferences and comparative cost-effectiveness analyses. The Clinical Guidelines Committee evaluated the following clinical outcomes using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach: pain freedom and pain relief at 2 hours; sustained pain freedom and sustained pain relief up to 48 hours; need for rescue medication within 24 hours; nausea, vomiting, and restored physical function at 2 hours; and overall and serious adverse events (AEs). Additional data on AEs were captured through U.S. Food and Drug Administration medication labels. Audience and Population: The audience for this clinical guideline is physicians and other clinicians. The population is adults with acute episodic migraine headache (defined as 1 to 14 headache days per month) managed in outpatient settings. Recommendation 1: ACP recommends that clinicians add a triptan to a nonsteroidal anti-inflammatory drug to treat moderate to severe acute episodic migraine headache in outpatient settings for nonpregnant adults who do not respond adequately to a nonsteroidal anti-inflammatory drug (strong recommendation; moderate-certainty evidence). Recommendation 2: ACP suggests that clinicians add a triptan to acetaminophen to treat moderate to severe acute episodic migraine headache in outpatient settings for nonpregnant adults who do not respond adequately to acetaminophen (conditional recommendation; low-certainty evidence).

🌍 What if Earth was no longer ours? Imagine a reality where alien fungal lifeforms took over the planet, reshaping cities, nature, and even human civilization itself.

👁️ This AI-generated Sci-Fi short film is a mind-bending journey into an alternate Earth—a world overtaken by bioluminescent alien fungi, spore-based civilizations, and an eerie, surreal atmosphere.

🔬 Inspired by nature’s most resilient organisms, this vision of the future combines biology, science fiction, and cosmic horror into one epic cinematic experience!

🎧 Best experienced with headphones!
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💡 Created with:
🎨 MidJourney V6.1 (AI Art)
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