A post on the Croppie website, for crop circle enthusiasts, described the new pictogram as a ‘reproduction, remaster, even, of the most iconic crop circle of all time’ Cover versions might never quite be as good as the original – but this remaster of a rock classic looks just like the real thing.
A meteor has exploded over the Atlantic Ocean with the force of the atomic bomb dropped on Hiroshima. It’s one of the ways that civilisation as we know it could end, with an asteroid impact sending the human race the way of the dinosaurs. It’s a terrifying prospect, and the film Don’t Look Up with Jennifer Lawrence and Leonardo DiCaprio really didn’t help matter with its demonstration of the paralysis and greed which could doom humanity.
It’s surprisingly reassuring. Aside from “breathing”, “sleeping”, and “putting on Troy McClure’s accent every time you say his name”, I reckon panicking about death is one of the most universal human experiences. Obviously, part of the problem of wondering what happens when you die is that nobody with any real qualifications can answer you.
When Demi Washington, a basketball player at Vanderbilt University came down with COVID-19 in late 2020, her symptoms were mild, just a runny nose. But to ensure her safe return to the court, the school required her to undergo an MRI. The results brought Washington to tears.
This has been announced by Pulsar Fusion, the company responsible for its manufacture. The name Pulsar Fusion may not be familiar to most people, but it may soon achieve an unprecedented milestone in the world of nuclear fusion. Although there are many steps to take, Pulsar Fusion has been working since 2013 to achieve a rocket that breaks all known barriers to date.
Researchers think they understand the conditions which see the precious stones erupt to the Earth’s surface from far below where they are formed.
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One of the oldest known molecules, the ribosome, creates proteins based on a copy of the genetic code found in the genome, known as mRNA. Scientists have believed that the ribosome performed the same type of work with all mRNA, like a standardized assembly line that it did not regulate on its own. However, researchers from the University of Copenhagen have discovered this is not the case.
Their findings are published in the journal Developmental Cell in an article entitled “Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions.”
“It has long been known that there are different types of ribosomes. But it has been assumed that no matter what mRNA you give the ribosome, it will produce a protein. But our results suggest that different types of ribosomes produce specific proteins,” says Anders H. Lund, professor at the Biotech Research and Innovation Center at the University of Copenhagen.
Recombinant adeno-associated virus (rAAV) vectors are a cornerstone of genetic medicine. These hollow virus particles are used to deliver commercial gene therapies like Glybera and Luxturna, as well as many other candidates still in development.
Despite this, the biopharmaceutical industry has yet to find the most effective way of making rAAV vectors at scale. McKinsey analysts recently described vector production as one of the major challenges faced by gene therapy developers. And the situation is only going to get worse as the gene therapy market evolves and begins developing products for larger patient populations.
“With a shift beyond ultra-rare indications, viral-vector manufacturing requires rapid expansion to be able to address various diseases in the commercial space,” the analysts wrote, adding, “The broader application of viral vector-based gene therapies (for example, to more common diseases) requires higher yields and lower cost of goods (COGs).”
