Lifeboat Foundation

Karin’s life took a dramatic turn when a farming accident claimed her right arm more than 20 years ago. Since then, she has endured excruciating phantom limb pain. “It felt like I constantly had my hand in a meat grinder, which created a high level of stress and I had to take high doses of various painkillers.”

In addition to her intractable pain, she found that conventional prostheses were uncomfortable and unreliable, and thus of little help in daily life. All this changed when she received groundbreaking bionic technology that allowed her to wear a much more functional prosthesis comfortably all day. The higher integration between the bionics and Karin’s residual limb also relieved her pain. “For me, this research has meant a lot, as it has given me a better life.”

Mechanical attachment and reliable control are two of the biggest challenges in artificial limb replacement. People with limb loss often reject even the sophisticated prostheses commercially available due to these reasons, after experiencing painful and uncomfortable attachment with limited and unreliable controllability.

Automation and sector-wide collaboration will be critical as developers try to move beyond the production challenges that slow growth of the cell and gene therapy sector. So says Julie G. Allickson, PhD, director of Mayo Clinic’s Center for Regenerative Biotherapeutics who argues that, despite considerable investment in infrastructure, production is still the biggest challenge.

“Both industry and academia are challenged by the lack of manufacturing capacity for cell and gene therapies,” she says, citing plasmid production and viral vector production as examples. “Besides these issues, the scalability of production processes can be difficult, especially when coupled to individually expanded cells. When looking at the patient cells variability, quantity and quality of cells is critical to ensure consistency in the product delivered to the patient,” she says.

Tesla has launched an official Application Programming Interface (API) for its vehicles, indicating that the company could be looking at debuting its own app store soon.

Without sharing all the system details, Tesla has launched an initial tier of its own API that’s expected to evolve into next year and will eventually cost money, according to a report from Not a Tesla App earlier this week. The new API tier is called the “Discovery Tier,” and while it’s currently free, that’s expected to change moving into 2024 — though Tesla has yet to detail price points or plans for additional tiers.

Eventually, Tesla is likely to debut its own App Store, generating money from developers who want to develop and host their own services and apps on the automaker’s in-car platform. The current Tesla API is primarily geared toward fleet management, as seen in the Not a Tesla App image below or on the company’s website here.

Many think this lithium ion alternative will nearly double vehicle range and reduce charging time, dramatically changing the perception and performance of electric vehicles.

The preferred “handedness” of biomolecules could have emerged from interactions between electrons and magnetic surfaces on primordial Earth, new research suggests.

One of the biggest unknowns regarding the upcoming Tesla Cybertruck was and still is its size, but a set of new photos posted online on the Cybertruck Owners Club forum shed some light on the matter.

In the images (embedded below), a release candidate (RC) Cybertruck is stopped at a Tesla Supercharger, and a Rivian R1T is parked right next to it, giving us an idea of what to expect when the angular all-electric pickup hits the market toward the end of this year (probably).

Judging from the photos, the Cybertruck seems a bit wider and longer than the R1T. For reference, Rivian’s pickup measures 217.1 inches long, 81.8 in wide (with the side mirrors folded), and 78.2 in tall (with the antenna accounted for and the suspension in its highest setting).

The strange science experiment that blew a worm’s head off… and blew our minds.

This interview is an episode from @The-Well, our publication about ideas that inspire a life well-lived, created with the @JohnTempletonFoundation.

Continue reading “The beauty of collective intelligence, explained by a developmental biologist” »

The Collective Intelligence of Cells During Morphogenesis: What Bioelectricity Outside the Brain Means for Understanding our Multiscale Nature with Michael Levin — Incredible Minds.

Recorded: April 29, 2023.

Continue reading “Incredible Minds: The Collective Intelligence of Cells During Morphogenesis with Dr. Michael Levin” »

Lectiure by Gregory Bateson.