Lifeboat Foundation

A new study has shed light on why having two copies of each chromosome is crucial, identifying a mechanism that maintains biallelic gene dosage.

Researchers have identified a suite of genes that influence head shape in humans, helping to explain head shape diversity and potentially conditions affecting the skull.

Beyond glycemic benefits, users of the app also reported significantly less-related emotional distress than standard care (−1.9 vs 1.7 points in composite survey scores, P =0.03).

“We are currently working on making technology like this accessible to patients outside of research settings because we think it can really help patients in underserved areas who need high-touch care to get their under control,” Nayak said.

The researchers developed their custom voice-based AI app and had it powered by Alexa (Amazon wasn’t involved with the study). The software was equipped with titration algorithms by the American Association of Clinical Endocrinologists and the American College of Endocrinology and included emergency protocols to handle hypoglycemia and hyperglycemia.

A key stress neurotransmitter is increased during heavy alcohol drinking, and may play a role in alcohol withdrawal symptoms, reports a new study in mice.

The field of research focusing on self-propelled particles, known as active particles, is rapidly expanding. In most theoretical models, these particles are assumed to maintain a constant swimming speed. However, this assumption does not hold true for many experimentally produced particles, like those propelled by ultrasound for medical applications. Their propulsion speed varies with orientation.

A team of physicists, led by Prof. Raphael Wittkowski from the University of Münster and including Prof. Michael Cates from the University of Cambridge, conducted a collaborative study to explore how this orientation-dependent speed influences the behavior of particle systems, particularly in cluster formation.

They combined computer simulations with theoretical analysis to uncover new effects in systems of active particles with orientation-dependent speeds. Their findings were recently published in the journal Physical Review Letters.

In the era of big data and advanced artificial intelligence, traditional data storage methods are becoming inadequate. To address the need for high-capacity and energy-efficient storage solutions, the development of next-generation technologies is crucial.

Among these is resistive random-access memory (RRAM), which relies on altering resistance levels to store data. A recent study published in the journal Angewandte Chemie details the work of a research team who have pioneered a method for creating supramolecular memristors, one of the key components in the construction of nano-RRAM.

Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient antiviral immunity characterized by failure to eliminate HBV-infected hepatocytes is associated with chronic hepatitis B. Prophylactic vaccination against hepatitis B successfully established protective immunity against infection with the hepatitis B virus and has been instrumental in controlling hepatitis B. However, prophylactic vaccination schemes have not been successful in mounting protective immunity to eliminate HBV infections in patients with chronic hepatitis B.

Painless lesions investigated in mice

Now, for the first time, researchers have looked into the lesions on mouse skin to assess if there are any metabolic signalling pathways that are responsible for thwarting pain. The aim is to hopefully use this mechanism to help people suffering from debilitating pain through the development of non-narcotic pain medications.

“No one knows why these lesions are painless – but it has been thought that the parasite somehow manipulates the host physiological system,” said Abhay Satoskar, senior author of the study and professor of pathology in The Ohio State University College of Medicine.

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