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Jan 24, 2024

Optoacoustic Cooling of Traveling Hypersound Waves

Posted by in category: quantum physics

We experimentally demonstrate optoacoustic cooling via stimulated Brillouin-Mandelstam scattering in a 50 cm long tapered photonic crystal fiber. For a 7.38 GHz acoustic mode, a cooling rate of 219 K from room temperature has been achieved. As anti-Stokes and Stokes Brillouin processes naturally break the symmetry of phonon cooling and heating, resolved sideband schemes are not necessary. The experiments pave the way to explore the classical to quantum transition for macroscopic objects and could enable new quantum technologies in terms of storage and repeater schemes.

Jan 24, 2024

Researchers design new open-source technology for interfacing with living neurons

Posted by in categories: biological, neuroscience

Mind In Vitro Platforms: Versatile, Scalable, Robust, and Open Solutions to Interfacing with Living Neurons.


Neurons intricately communicate and respond to stimuli within a vast network, orchestrating essential functions from basic bodily processes to complex thoughts. Traditional neuroscience methods, relying on in vivo electrophysiology (within a living organism), often have difficulty addressing the complexity of the brain as a whole.

An alternative approach involves extracting cells from the organism and conducting studies on a culture dish instead (in vitro), providing researchers with enhanced control and precision in measuring neural processes.

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Jan 24, 2024

Liquid lithium on the walls of a fusion device helps the plasma within maintain a hot edge

Posted by in categories: nuclear energy, particle physics

Emerging research suggests it may be easier to use fusion as a power source if liquid lithium is applied to the internal walls of the device housing the fusion plasma.

Plasma, the fourth state of matter, is a hot gas made of electrically charged particles. Scientists at the Department of Energy’s Princeton Plasma Physics Laboratory (PPPL) are working on solutions to efficiently harness the power of fusion to offer a cleaner alternative to fossil fuels, often using devices called tokamaks, which confine plasma using magnetic fields.

“The purpose of these devices is to confine the energy,” said Dennis Boyle, a staff research physicist at PPPL. “If you had much better energy confinement, you could make the machines smaller and less expensive. That would make the whole thing a lot more practical, and cost-effective so that governments and industry want to invest more in it.”

Jan 24, 2024

The True Story of How GPT-2 Became Maximally Lewd

Posted by in categories: materials, robotics/AI

In this video, we recount an incident that occurred at OpenAI while researchers were trying to finetune GPT-2 to be as helpful and ethical as possible. It’s narrated that inadvertently flipping a single minus sign led GPT-2 to become the embodiment of a well-known cardinal sin.

#ai #aisafety #alignment.

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Jan 23, 2024

Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function

Posted by in categories: biotech/medical, genetics

Year 2018 Age related symptoms may be even more simple to reverse by recharging the mitochondria then eventually we can have genetically engineered mitochondria to run longer so the cycles of the human body could run indefinitely.


Singh, B., Schoeb, T.R., Bajpai, P. et al. Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function. Cell Death Dis 9, 735 (2018). https://doi.org/10.1038/s41419-018-0765-9

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Jan 23, 2024

Brain-based computing chips not just for AI anymore

Posted by in categories: biotech/medical, finance, mathematics, robotics/AI

With the insertion of a little math, Sandia National Laboratories researchers have shown that neuromorphic computers, which synthetically replicate the brain’s logic, can solve more complex problems than those posed by artificial intelligence and may even earn a place in high-performance computing.

The findings, detailed in a recent article in the journal Nature Electronics, show that neuromorphic simulations employing the statistical method called random walks can track X-rays passing through bone and soft tissue, disease passing through a population, information flowing through social networks and the movements of financial markets, among other uses, said Sandia theoretical neuroscientist and lead researcher James Bradley Aimone.

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Jan 23, 2024

Stanford professor on the future of life-saving medicine | Steve Quake

Posted by in categories: biotech/medical, robotics/AI

What if AI could tell us we have cancer before we show a single symptom? Steve Quake, head of science at the Chan Zuckerberg Initiative, explains how AI can revolutionize science.

Up next, Harvard professor debunks the biggest exercise myths ► • Harvard professor debunks the biggest…

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Jan 23, 2024

2023 Moon to Mars Architecture Concept Review Outcomes Released by NASA

Posted by in categories: biological, physics, space travel

NASA’s Moon to Mars Architecture has been instrumental in developing, designing, and executing the long-term goals of establishing not only a permanent human presence on the Moon but sending humans to Mars, someday. Today, NASA announced the results from the recent 2023 Moon to Mars Architecture Concept Review, which outlines key objectives, strategies, and key decisions in establishing a human presence on Mars in the future.

The Concept Review discussed in detail the architecture objectives and segments for not only returning humans to the Moon but establishing a long-term presence there through testing new technologies, systems, and equipment that would be used on an eventual human mission to Mars. the Moon to Mars Objectives cover a myriad of goals, including lunar and planetary science, heliophysics, human and biological science, physics and physical sciences, science enabling, applied science, lunar infrastructure, Mars infrastructure, transportation and habitation, and operations.

“Over the last year we’ve been able to refine our process for Moon to Mars architecture concept development to unify the agency,” Nujoud Merancy, who is the Deputy Associate Administrator for Strategy & Architecture for NASA’s Exploration Systems Development Mission Directorate (ESDMD), said in a statement. “Our process in the coming months will focus on addressing gaps in the architecture and further reviewing the decisions the agency needs to make to successfully mount crewed Mars missions.”

Jan 23, 2024

CheXagent: Towards a Foundation Model for Chest X-Ray Interpretation

Posted by in category: futurism

Join the discussion on this paper page.

Jan 23, 2024

Scientists Coax Bacteria Into Making Exotic Proteins Not Found in Nature

Posted by in category: robotics/AI

A Whole New World

Scientists have already found hundreds of exotic amino acids. AI models such as AlphaFold or RoseTTAFold, and their variations, are likely to spawn even more. Finding carriers and “glue” proteins that match has always been a roadblock.

The new study establishes a method to speed up the search for new designer proteins with unusual properties. For now, the method can only incorporate four synthetic amino acids. But scientists are already envisioning uses for them.