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A balance of infection and harmony called endosymbiosis helps shape evolution. For the first time, biologists have reproduced this arrangement between microbes in a lab.

So much of life relies on endosymbiotic relationships, but scientists have struggled to understand how they happen. How does an internalized cell evade digestion? How does it learn to reproduce inside its host? What makes a random merger of two independent organisms into a stable, lasting partnership?

Now, for the first time, researchers have watched the opening choreography of this microscopic dance by inducing endosymbiosis in the lab(opens a new tab). After injecting bacteria into a fungus — a process that required creative problem-solving (and a bicycle pump) — the researchers managed to spark cooperation without killing the bacteria or the host. Their observations offer a glimpse into the conditions that make it possible for the same thing to happen in the microbial wild.


Evolution was fueled by endosymbiosis, cellular alliances in which one microbe makes a permanent home inside another. For the first time, biologists made it happen in the lab.

Over a decade after its discovery, the Higgs boson, often referred to as the “God particle,” continues to captivate physicists and deepen our understanding of the universe. Recent findings from the Max Planck Institute promise to unravel even more about this enigmatic particle, potentially opening doors to uncharted realms of particle physics.

The Higgs boson is a cornerstone of the Standard Model of particle physics, responsible for answering one of the universe’s most fundamental questions: how do particles gain mass? This phenomenon hinges on the Higgs field, an invisible energy field that permeates the cosmos. To visualize this, imagine wading through a pool filled with water versus thick foam. While water might let you glide, the foam slows you down—this interaction mirrors how particles gain mass as they traverse the Higgs field. Without it, the building blocks of matter as we know them couldn’t exist.

Why Understanding Higgs Interactions Matters?

AUSTIN, Texas — An Austin entrepreneur is making waves in the world of Artificial Intelligence (AI) by setting his sights on Artificial General Intelligence (AGI). AGI is a type of AI that aims to create machines with human-like learning and reasoning abilities.

“In 2002, together with two other people, I coined the term Artificial General Intelligence.” Founder and CEO of Aigo.ai said.

Voss says that was always the original goal of AI to build thinking machines.

Tomiko Itooka, a Japanese woman who was the world’s oldest person according to Guinness World Records, has died, an Ashiya city official said Saturday. She was 116.

Yoshitsugu Nagata, an official in charge of elderly policies, said Itooka died on December 29 at a care home in Ashiya, Hyogo Prefecture, central Japan.

Itooka, who loved bananas and a yogurt-flavored Japanese drink called Calpis, was born on May 23, 1908. She became the oldest person last year following the death of 117-year-old Maria Branyas, according to the Gerontology Research Group.

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The work, published today in Nature, marks a significant step forward in our ability to study how the human body takes shape during early development.

The notochord, a rod-shaped tissue, is a crucial part of the scaffold of the developing body. It is a defining feature of all animals with backbones and plays a critical role in organising the tissue in the developing embryo.

Despite its importance, the complexity of the structure has meant it has been missing in previous lab-grown models of human trunk development.

In this research, the scientists first analysed chicken embryos to understand exactly how the notochord forms naturally. By comparing this with existing published information from mouse and monkey embryos, they established the timing and sequence of the molecular signals needed to create notochord tissue.

There might not be a mysterious ‘dark’ force accelerating the expansion of the Universe after all. The truth could be much stranger – bubbles of space where time passes at drastically different rates.

The passage of time isn’t as constant as our experience with it suggests. Areas of higher gravity experience a slower pace of time compared with areas where gravity is weaker, a fact that could have some pretty major implications on how we compare rates of cosmic expansion according to a recently developed model called timescape cosmology.

Discrepancies in how fast time passes in different regions of the Universe could add up to billions of years, giving some places more time to expand than others. When we look at distant objects through these time-warping bubbles, it could create the illusion that the expansion of the Universe is accelerating.

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, judgement, and awareness behind Alzheimer’s disease.

Blocking this pathway in mouse brains modeled on Alzheimer’s prevented damage to their synapse connections and reduced the buildup of potentially toxic tau proteins – both hallmarks of the condition.

The researchers, led by a team from the City University of New York (CUNY), believe this pathway – called the integrated stress response (ISR) – causes brain immune cells called microglia to go ‘dark’ and start damaging rather than benefiting the brain.