Summary: A new international study reveals that schizophrenia manifests differently in the brain, reflecting the wide range of symptoms among patients. Researchers analyzed imaging data from over 6,000 individuals and found that while some brain structures vary significantly, others remain highly uniform.
Brain folding patterns in the mid-frontal region were consistently similar across patients, suggesting a less flexible developmental process in early childhood. These findings highlight the need for precision medicine approaches tailored to each patient’s neurobiological profile.
Summary: A new study reveals how prenatal infections followed by early-life stress—known as “two-hit stress”—can lead to brain dysfunction and psychiatric-like behaviors. Researchers found that affected mice showed abnormal cerebellar activity, increased microglial turnover, and impaired brain-wide connectivity.
Notably, microglia replacement therapy successfully reversed these effects, offering a potential new approach for mental health treatments. The findings suggest that sex differences may influence stress resilience, highlighting the need for personalized treatments for psychiatric and neurodegenerative disorders.
The next step involves fetching and executing a Python script from the same SharePoint location that serves as a shellcode loader for KaynLdr, a reflective loader written in C and ASM that’s capable of launching an embedded DLL, in this the Havoc Demon agent on the infected host.
“The threat actor uses Havoc in conjunction with the MicrosoQ Graph API to conceal C2 communication within well-known services,” Fortinet said, adding the framework supports features to gather information, perform file operations, as well as carry out command and payload execution, token manipulation, and Kerberos attacks.
The development comes as Malwarebytes revealed that threat actors are continuing to exploit a known loophole in Google Ads policies to target PayPal customers with bogus ads served via advertiser accounts that may have been compromised.
Phase transitions are a familiar part of life, representing predictable paths by which solids turn to liquids, mixtures turn to solutions, magnets become nonmagnetic. Temperature plays a central role in driving many phase transitions, however there are others that don’t depend on temperature at all—such as instabilities in social networks, bird flocking, and even the process of visual recognition in humans. Phase transitions represent change that impacts all length scales from the tiniest to the global, becoming permanent on time scales from the shortest to the longest. Most enigmatic are phase transitions that happen only at zero temperature, driven by the intrinsic quantum mechanical nature of matter. How are these quantum phase transitions different from temperature driven phase transitions? What are the different phases that can be explored by quantum systems at zero temperature? Living as we do at nonzero temperature, can we experience quantum phenomena that occur at zero temperature? Phase transitions and the ways in which they pattern space and time are at the heart of our developing understanding of quantum matter.
Meigan Aronson is an experimental condensed matter physicist whose research centers on the discovery and exploration of quantum materials. She received her undergraduate degree from Bryn Mawr College, and her PhD in Physics from the University of Illinois at Urbana-Champaign. After a postdoc at Los Alamos National Laboratory, she enjoyed faculty positions at the University of Michigan and at Stony Brook University, where she was also a group leader at Brookhaven National Laboratory. Her research uses neutron scattering to study the emergence of new phases of matter, especially novel types of order that are only found near quantum phase transitions. She is a Fellow of the American Physical Society and the Neutron Scattering Society of America, and has received the Department of Defense National Security Science and Engineering Fellowship. She is currently a Professor in the Department of Physics and Astronomy and a Principal Investigator at the Stewart Blusson Quantum Matter Institute at The University of British Columbia, where she also served as Dean of the Faculty of Science.
This public lecture was recorded at Aspen Center for Physics on Wednesday, February 26, 2025. Thank you to the Nick and Maggie DeWolf Foundation for making our winter lecture series possible since 1985.