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Feb 15, 2024

Study: Traumatic brain injury leads to widespread changes in neural connections

Posted by in categories: biotech/medical, health, neuroscience

A head injury serious enough to affect brain function, such as that caused by a car accident or sudden fall, leads to changes in the brain beyond the site of impact, Tufts University School of Medicine scientists report in the journal Cerebral Cortex. In an animal model of traumatic brain injury, the researchers found that both hemispheres work together to forge new neural pathways in an attempt to replicate those that were lost.

“Even areas far away from the injury behaved differently immediately afterward,” says first author Samantha Bottom-Tanzer, an MD/Ph. D. student in neuroscience at the School of Medicine. “Traumatic brain injury research tends to focus on the region of injury, but this study makes a good case that the entire brain can be affected, and imaging in distal regions can provide valuable information.”

Bottom-Tanzer and colleagues are the first to use an combining fluorescent sensors of neuronal activity and electrodes to record how many parts of the brain talk to each other after a brain injury. The team tracked neural activity in mice for up to three weeks post-injury during periods of exercise and rest.

Feb 15, 2024

Odysseus Spacecraft Launches in Bid for First U.S. Moon Landing Since 1972

Posted by in category: space travel

A U.S. company’s 14-foot-tall spacecraft began speeding to the moon, where the vehicle is expected to try to make history by pulling off the first-ever commercial lunar landing.

The lander, called Odysseus and developed by Houston-based Intuitive Machines, isn’t carrying crew, but rather is ferrying scientific and commercial payloads. It was launched at 1:05 a.m. ET Thursday from NASA’s Kennedy Space Center in Florida on a SpaceX rocket and later separated from the upper part of that vehicle to start a roughly 239,000-mile journey, according to a livestream.

The spacecraft had a successful launch and connected to radio communications with the company’s mission operations center in Houston, Intuitive Machines said.

Feb 15, 2024

SpaceX launches mission to the moon that could make history

Posted by in category: space travel

SpaceX has launched a mission to the moon that will make history if it achieves a successful landing on the lunar surface week.

Feb 15, 2024

Nova-C Launch: A New Chapter in Lunar Exploration Begins

Posted by in categories: economics, space

No American spacecraft has made a soft landing on the Moon since NASA’s Apollo 17 in 1972, but that could change soon as the Intuitive Machines’ Nova-C lander launched from the historic Launch Complex 39A at NASA’s Kennedy Space Center at 1:05 am EST (10:05 pm PST) last night. With a currently scheduled landing date of February 22, Nova-C (also called IM-1 Odysseus) is slated to land in Malapert-A crater, which is approximately 190 miles (300 kilometers) from the Moon’s south pole. This landing will also mark the first time a private company will perform a soft landing on the Moon and holds the potential to test technologies that could be used on future human missions with NASA’s Artemis program.

“NASA scientific instruments are on their way to the Moon – a giant leap for humanity as we prepare to return to the lunar surface for the first time in more than half a century,” NASA Administrator Bill Nelson said in a statement. “These daring Moon deliveries will not only conduct new science at the Moon, but they are supporting a growing commercial space economy while showing the strength of American technology and innovation. We have so much to learn through CLPS flights that will help us shape the future of human exploration for the Artemis Generation.”

The science instruments that will be traveling with Nova-C include the Lunar Node 1 Navigation Demonstrator, Laser Retroreflector Array, Navigation Doppler Lidar for Precise Velocity and Range Sensing, Radio Frequency Mass Gauge, Radio-wave Observations at the Lunar Surface of the Photoelectron Sheath, and Stereo Cameras for Lunar Plume-Surface Studies. All these instruments are designed to investigate how spacecraft can both land and operate on the lunar surface, specifically near the south pole of the Moon.

Feb 15, 2024

Long-Term Outcomes After False-Positive Mammography Results

Posted by in category: biotech/medical

Previous research has suggested that false-positive mammogram results are associated with higher risk for subsequently developing breast cancer. To further examine this issue, researchers in Sweden used national mammography data to follow 500,000 women (median age, 52) during 30 years (1991–2020). About 45,000 women had false-positive results (i.e., they were recalled for further evaluation but didn’t receive diagnoses of breast cancer at that time). Women with false-positive results were matched with controls to compare rates of subsequent breast cancer diagnosis.

The results include:

Feb 15, 2024

‘Beyond what’s possible’: New JWST observations unearth mysterious ancient galaxy

Posted by in category: cosmology

Our understanding of how galaxies form and the nature of dark matter could be completely upended after new observations of a stellar population bigger than the Milky Way from more than 11 billion years ago that should not exist.

A paper published today in Nature details findings using new data from the James Webb Space Telescope (JWST). The results find that a in the —observed 11.5 billion years ago (a cosmic redshift of 3.2)—has an extremely old population of stars formed much earlier—1.5 billion years earlier in time (a redshift of around 11). The observation upends current modeling, as not enough dark matter has built up in sufficient concentrations to seed their formation.

Swinburne University of Technology’s Distinguished Professor Karl Glazebrook led the study and the international team, who used the JWST for spectroscopic observations of this massive quiescent galaxy.

Feb 15, 2024

Generative AI could be society’s new equalizer. Here’s why

Posted by in category: robotics/AI

An expert highlights how generative #AI could distribute #productivity gains across multiple social sectors and act as a balance wheel for wider society.

Feb 15, 2024

OpenAI Hiring Detective to Find Who’s Leaking Its Precious Info

Posted by in categories: robotics/AI, security

OpenAI is looking to hire an “insider risk investigator” to “fortify our organization against internal security threats.”

According to the company’s job listing, first spotted by MSPowerUser, the gumshoe is supposed to help the company safeguard its assets by “analyzing anomalous activities, promoting a secure culture, and interacting with various departments to mitigate risks.” Per the Wayback Machine, the job listing has been up since mid-January.

“You’ll play a crucial role in safeguarding OpenAI’s assets by analyzing anomalous activities, promoting a secure culture, and interacting with various departments to mitigate risks,” the listing reads. “Your expertise will be instrumental in protecting OpenAI against internal risks, thereby contributing to the broader societal benefits of artificial intelligence.”

Feb 15, 2024

Engineer designs molecules for our quantum future

Posted by in categories: engineering, quantum physics

Editor’s note: This story is part of Meet a UChicagoan, a regular series focusing on the people who make UChicago a distinct intellectual community. Read about the others here.

Wide is the spectrum of scientific inquiry, ranging from the philosophical— What is information?—to the banal — Where did I put that Allen wrench?

For University of Chicago graduate student Chloe Washabaugh, there is joy to be found in all of it. A Ph.D. student in quantum engineering at the Pritzker School of Molecular Engineering, Washabaugh fashions molecules into tiny quantum information processors, designing them to sense, send or store data—whatever the need.

Feb 15, 2024

New Mechanism Reveals How Tumors Evade Immune Detection

Posted by in category: biotech/medical

Scientists have dedicated their lives to finding a cure for cancer. America became a science hub for cancer research, particularly after President Richard Nixon declared the “war on cancer” in 1971. As a result, extensive research has been published on how cancer functions and different ways to target both solid and hematologic malignancies. Unfortunately, there is currently not a cure for cancer. Although some patients are treated and enter remission, tumors can reoccur. In addition, some tumor types are harder to treat than others. Although the science community is hopeful to effectively treat each type of cancer, more work is needed to discern why some tumors are harder to treat than others.

Many tumors evade the immune system through different mechanisms and mutations. Therapy-resistant cells may stay dormant for a period of time before proliferating, which results in cancer recurrence. Additionally, different surface markers prevent immune cell activation which target cancer. This allows the tumor to proliferate without an immune cell response. Many different immunotherapies being developed target these surface markers to activate T cells, which kill or lyse infections. The type of immunotherapy that refers to the blockade of cell-to-cell interactions is known as checkpoint inhibitors. Checkpoint proteins are surface markers that help the immune cell differentiate from self. More specifically, these cells provide a signal for immune cells to avoid lysing healthy cells and protect from autoimmunity. However, tumors use a selection of checkpoint proteins to avoid immune cell detection.