EPFL researchers have developed a powerful method to generate brain-wide, biologically realistic wiring maps of the mouse brain. Their approach bridges experimental data with mathematical and computational modeling to simulate how neurons connect across the entire brain.
The study is published in the journal Nature Communications.
One of neuroscience’s greatest challenges is understanding how the brain is wired. Even with modern imaging tools, it has been a challenge to create detailed maps that show how the brain’s billions of cells (neurons) connect, not just with their local “neighbors” but also to other, more distant cells in the brain.