Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 12440

This is cross-posted from my blog. This milestone by SpaceX is directly relevant to programs by Lifeboat such as the AsteroidShield and SpaceHabitat, and possibly also (eventually) to Space-Based Solar Power.

SpaceX Falcon 1 Rocket Launch photo

Stars My Destination
After the third try, Elon Musk, the founder of SpaceX, co-founder of Paypal, chairman of SolarCity and chairman of Tesla Motors (beat that resumé!) was interviewed by WIRED about the difficulties of making his space rockets reach orbit:

Wired.com: How do you maintain your optimism?

Musk: Do I sound optimistic?

Wired.com: Yeah, you always do.

Musk: Optimism, pessimism, fuck that; we’re going to make it happen. As God is my bloody witness, I’m hell-bent on making it work.

Falcon 1: The First Privately Developed Rocket to Orbit the Earth
Well kids, perseverance pays off. On the 4th try, the 70-foot Falcon 1 rocket reached orbit wit a 364-pound dummy payload: “The data shows we achieved a super precise orbit insertion — middle of the bullseye — and then went on to coast and restart the second stage, which was icing on the cake.” Check out the video of the highlights of the launch.

“This really means a lot,” Musk told a crowd of whooping employees. “There’s only a handful of countries on Earth that have done this. It’s usually a country thing, not a company thing. We did it.”

Musk pledged to continue getting rockets into orbit, saying the company has resolved design issues that plagued previous attempts.

Last month, SpaceX lost three government satellites and human ashes including the remains of astronaut Gordon Cooper and “Star Trek” actor James Doohan after its third rocket was lost en route to space. The company blamed a timing error for the failure that caused the rocket’s first stage to bump into the second stage after separation.

SpaceX’s maiden launch in 2006 failed because of a fuel line leak. Last year, another rocket reached about 180 miles above Earth, but its second stage prematurely shut off.

The Falcon 1, at $7.9 million each, is what you could call the budget model. In fact, $7.9 million is basically pocket changed compared to what government agencies like NASA are used to paying to contractors like Lockheed Martin & co.

SpaceX is also working on the Falcon 9 (12,500 kg to low Earth orbit, and over 4,640 kg to geosynchronous transfer orbit) and Falcon 9 Heavy (28,000 kg to low Earth orbit, and over 12,000 kg to geosynchronous transfer orbit) to help NASA reach the International Space Station, among other things. These should cost between $36.75 million and $104 million each depending on the model and mission, and the first launch is scheduled for the first quarter of 2009.

Continue reading “SpaceX Falcon 1 Rocket Reaches Orbit on 4th Try” | >

Open source has emerged as a powerful set of principles for solving complex problems in fields as diverse as education and physical security. With roughly 60 million Americans suffering from a chronic health condition, traditional research progressing slowly, and personalized medicine on the horizon, the time is right to apply open source to health research. Advances in technology enabling cheap, massive data collection combined with the emerging phenomena of self quantification and crowdsourcing make this plan feasible today. We can all work together to cure disease, and here’s how.

Read more…

1. Language and cultural isolation lead to the situation then Russian researches are not known in West and vice versa. I spent a lot of time translating into Russian and promoting works of Bostrom, Yudkowsky, Circovic, D.Brin, Freitas, A.Kent and other writers on global risks. Here I would like to tell you about some Russian researchers. Though I can’t prove validity of their ideas I think they should be checked internationally in order to roll out them or to take preventive measures. A. V. Karnauhov created a theory of “green house” catastrophe. He shows that climate is non linear system this many positive feedbacks and one of them is often missed – it is that water vapor is also greenhouse gas and growing temperatures would lead to injection of more and more water vapor into atmosphere. Also current level of carbon dioxid should lead to much more temperature increase, but inertia of ocean temperature makes current temperature smaller. But ocean temperature will rise, especially in Arctic, where large amounts of methane stored under seebed on the low shallow waters. This would lead to clarhat gun explosion of metane. Cumulative effect of water vapor, CO2, Metane and surmounting of ocean inertia will lead to very quick exponential global warming, which could have devastating effects as early as in 2020th and make global temperature higher not on 6 degrees but on several tens to the end of the century – which would mean human extinction, and after 200 years all life extinction on Earth Some his ideas you could see in the article: http://www.poteplenie.ru/doc/role.pdf Karnaukhov A.V. Role of the biosphere in the formation of the Earth’s Climate: The Greenhouse Catastrophe, Biophysics, Vol.46, No 6, 2001, pp. 1078–1088. Also I should mention works of Drobishevsky “Danger of the explosion of Callisto and the priority of space missions” http://www.springerlink.com/content/584mw0407824nt72/ He thinks that Jovian satellite Callisto could soon explode because of H and O reaction in its ice. Such explosion will lead to bombardment of the earth by comets and “nuclear winter” for 60 years. He suggested to send there a space mission. But I wrote him that, if he is write, it is very dangerous to send where mission, because it could trigger the explosion by drilling the ice crust. And the last man, about whom I would like to tell you, is a reviewer of my book “the Structure of the global catastrophe” Aranowich, who told me by way that his group has created much more effective way to penetrate the earth crust the Stevenson’s probe. Stevenson’s probe require 10 million ton of melted iron. His probe will weight only 10 tons and will use an energy of radioactive decay. It could reach 1000 km depth by one month – and the main danger is creation of supervolcano. Then I asked him, was any safety analysis done – he said not. But this is only theoretical work and no practical realization is planned.
2. I have wrote a book “The structure of global catastrophe” which aim was to investigate how different scenarios of global risks could interact in time, because all of them could realize in the XXI century. This book is sponsored by Russian Transhumanist movemet. Nick Bostrom wrote short preface to it. The book is mostly ready, but some editorial and organizational problems still persists. I hope it will be published by the end of the year.
3. I am started to translate this book into English. I have translated it by computer and then edit the result – now I am on the page 27 of 390. I need someone with native English who could help me to edit this translation. The book is here: http://avturchin.narod.ru/sgkengl2.doc I hope to finish English translation (in readable, but not high literature quality:) of the book until winter.
4. The shorter version of this book is already published on the name “War and 25 other scenarios of the End of the world”. This name was suggested by editorial house, the original name was: “Gnoseology of catastrophes”. The main idea of the book is that our inability to predict the future is equal to the end of the world.
5. I have translated the most part of Lifeboat site on Russian and I expect it will appear in the Net soon.
6. I have wrote several articles on the theme of global catastrophe: “Is SETI dangerous? English translation — http://www.proza.ru/texts/2008/04/12/55.html, “Atrophic principle and natural catastrophes” http://www.proza.ru/texts/2007/04/12-13.html and “About possibilities of manmade ignition of giant planets and other objects of Solar system” http://www.proza.ru/texts/2008/07/19/466.html which are in Russian.
7. I have created “Global catastrophic risks and human extinction library” there you could find many interesting literature on English and Russian. http://avturchin.narod.ru/Global.htm
8. I think that it is provable that if humanity will unite, it will have a chance to resist global risks, but if it will be divided on military competing parts, it almost doomed. Resent events on Caucasus put again in agenda the question of New cold war. Here we should ask what is the worst outcome of possible Cold war? Common answer is that Nuclear war is that worst outcome. But Nuclear war will not terminate all human population in most realistic scenarios. Much worse outcome is, I think, new arm race, which could lead to quick creation of much more destructive weapons, than nuclear. And the worst outcome of arm race is creation of Doomsday machine. Doomsday machine (DM) is ultimate defense weaponry. The example of such strategy was depicted by Kubrick in his genius movie “Dr. Strangelove”. Here we should say that DM-strategy is more suitable for a weaker state, which is in danger of aggression (or feels so). Quality of Russian nuclear forces is continue to deteriorating and minimum is expected around the year 2010 then most of old soviets rockets should be out of order. Simultaneously after the year 2010 US will rich a peak of their supremacy (because of thousand non nuclear cruise missiles, unique GPS system and antimissile shield it will have ability to make first strike without answer.), but later could lose supremacy because of economic crisis in US and growing arsenal of new Russian missiles. This situation looks dangerous, because from chess we know the principle: “Someone must attack under threat of losing his supremacy”. And antiballistic missile shield (ABM), which is developing now by NATO is very dangerous because it makes direct way to the creation of Doomsday Machine. Before ABM rockets were good as a mean of defense. But now only large underground bomb (gigaton order and with cobalt shield) could be a strategic defense. Such ideas is not only my creation but they are circulating in the air. Of course nobody is going to actually use such weapon, but it could be lunched accidentally. It should not be nuclear – it could be also large stockpile of anthrax, manmade supervulcano-threat or something more sophisticated. DM also could be used as a offensive mean. If Osama get it, he could say: everybody should convert in Islam, or I detonate it. The really big problem arise if in answer someone Catholic say: if anyone convert in Islam I will detonate my own Doomsday machine. In this case we finally doomed. But worst case scenarios are low probability ones, so I hope we have a chance to unite.

Following is a discussion of two potential threats to humanity – one which has existed for eons, the second we have seen recently resurfacing having thought it had been laid to rest.

First, a recent story on PhysOrg describes the work researchers at Vanderbilt University have performed in isolating antibodies from elderly people who had survived the 1918 flu pandemic. This comes three years after researchers at Mount Sinai and the Armed Forces Institute of Pathology in Washington, D.C isolated the same virus which caused this outbreak from the frozen bodies of people in Alaska who had died in the pandemic.

In addition to being an impressive achievement of biomedical science, which involved isolating antibody-secreting B cells from donors and generating “immortalized” cell lines to produce large amounts of antibodies, this research also demonstrates the amazing memory the immune system has (90 years!), as well as the ability scientists have to use tissue samples from people born nearly a century ago and fashion them into a potential weapon against future similar outbreaks. Indeed, these manufactured antibodies proved effective against 1918 flu virus when tested in mice.

Furthermore, such research provides tools which could help generate antibodies to treat other viruses which still blight humanity (such as HIV) or are seen as potential threats, such as avian influenza.

http://www.physorg.com/news138198336.html

Second, nuclear annihilation. Russia’s recent foray into Georgia and the ensuing tensions with the west have brought the specter of the cold war back from the dead, and with it increasing levels of aggressive rhetoric from both sides and more or less veiled threats of action, some of it diplomatic, some military.

During the past twenty years, ever since the fall of the former Soviet Union, we have become used to living in a world no longer directly and overtly threatened by complete annihilation through world war III. Is this about to change? It would seem that despite current tensions, present conditions are far from fostering a renewed cold war.

Modern day Russia (and China can be described along similar lines) is inexorably tied to the world economy and does not represent a conflicting ideology striving for world domination as was the case during the most of the latter half of the twentieth century. This deep international integration stems from the almost global acceptance of the market economy as the preferred driving force for economic growth, albeit under different forms of government. Both Russia and China are (currently) fueled more by the will being recognized as premier global forces rather than the will to rule the world, the former wishing to return to its previous position and reclaim the respect it feels it lost during the last couple of decades, and the latter rising anew after centuries in the shadows.

Of course, the coming elections in the US may change the tone prevalent in the international brinkmanship game, although the involvement of the EU, led by French premier Sarkozy means that such strong statements coming from Western Europe are not set to change fundamentally.

So, unless further surprises are in store for us (a possibility which cannot be ignored when dealing with political and military maneuvering, especially those involving the tense conditions prevalent in many of the former Soviet republics), a compromise will eventually be reached and respected. The seeds of a calming effort have already been felt in recent days with much less inflammatory declarations from both sides, and signs of a Russian willingness to tone down at least the public face of disagreements with the EU and US. This is likely set to continue…at least until the next outbreak of nationalistic violence or political sword-brandishing in a region in which tensions run high.

An interesting analysis of the current situation can be found at: http://www.cnn.com/2008/WORLD/europe/08/29/oakley.eu.russia/

The Singularity Institute for Artificial Intelligence has announced the details of The Singularity Summit 2008. The event will be held October 25, 2008 at the Montgomery Theater in San Jose, California. Previous summits have featured Nick Bostrom, Eric Drexler, Douglas Hofstadter, Ray Kurzweil, and Peter Thiel.

Keynote speakers include Ray Kurzweil, author of The Singularity is Near, and Justin Rattner, CTO of Intel. At the Intel Developer Forum on August 21, 2008, Rattner explained why he thinks the gap between humans and machines will close by 2050. “Rather than look back, we’re going to look forward 40 years,” said Rattner. “It’s in that future where many people think that machine intelligence will surpass human intelligence.”

Other featured speakers include:

  • Dr. Ben Goertzel, CEO of Novamente, director of research at SIAI
  • Dr. Marvin Minsky
  • Nova Spivack, CEO of Radar Networks, creator of Twine.com
  • Dr. Vernor Vinge
  • Eliezer Yudkowsky

You can find a comprehensive list of other upcoming Singularity and Artificial Intelligence events here.

Something to post to your websites and to vote online.

Aubrey de Grey can get $1.5 million for the Methuselah Foundation if enough people vote.

Voting ends September 1st, take a second to vote now.
Any US Amex cardmember or US resident (who makes a guest account) can vote.

Here is the page where you can vote “nominate”

The Methuselah Foundation Page with some more details if you are interested, to vote though you only need click on the above link…

The UK’s Guardian today published details of a report produced by Britain’s Security Service (MI5) entitled, ‘Understanding radicalization and violent extremism in the UK’. The report is from MI5’s internal behavioral analysis unit and contains within it some interesting and surprising conclusions. The Guardian report covers many of these in depth (so no need to go over here) but one point, which is worth highlighting is the claim made within the report that religion is and was not a contributory factor in the radicalization of the home-grown terrorist threat that the UK faces. In fact, the report goes on to state that a strong religious faith protects individuals from the effects of extremism.This viewpoint is one that is gathering strength and coincides with an article written by Martin Amis in the Wall Street Journal, which also argues that ‘terrorism’s new structure’ is about the quest for fame and thirst for power, with religion simply acting as a “means of mobilization”.

All of this also tends to agree with the assertion made by Philip Bobbit in ‘Terror and Consent’, that al-Qaeda is simply version 1.0 of a new type of terrorism for the 21st century. This type of terrorism is attuned to the advantages and pressures of a market based world and acts more like a Silicon Valley start-up company than the Red Brigades — being flexible, fast moving and wired — taking advantage of globalization to pursue a violent agenda.

This all somewhat begs the question of, what next? If al-Qaeda is version 1.0 what is 2.0? This of course is hard to discern but looking at the two certain trends, which will shape humanity over the next 20 years — urbanization and virtualization — throws up some interesting potential opponents who are operating today. The road to mass urbanization is currently being highlighted by the 192021 project (19 cities, 20 million people in the 21st century) and amongst other things, points to the large use of slum areas to grow the cities of the 21st century. Slum areas are today being globally exploited from Delhi to Sao Paulo by Nigerian drug organizations that are able to recruit the indigenous people to build their own cities within cities. This kind of highly profitable criminal activity in areas beyond the vision of government is a disturbing incubator.

150px-anonymousdemotivator.jpg
Increased global virtualization complements urbanization as well as standing alone. Virtual environments provide a useful platform for any kind of real-life extremist (as is now widely accepted) but it is the formation of groups within virtual spaces that then spill-out into real-space that could become a significant feature of the 21st century security picture. This is happening with, ‘Project Chanology’ a group that was formed virtually with some elements of the Anonymous movement in order to disrupt the Church of Scientology. While Project Chanology (WhyWeProtest Website)began as a series of cyber actions directed at Scientology’s website, it is now organizing legal protests of Scientology buildings. A shift from the virtual to the real. A more sinister take on this is the alleged actions of the Patriotic Nigras — a group dedicated to the disruption of Second Life, which has reportedly taken to using the tactic of ‘swatting’ — which is the misdirection of armed police officers to a victim’s home address. A disturbing spill-over into real-space. Therefore, whatever pattern future terrorist movements follow, there are signs that religion will play a peripheral rather than central role.

Originally posted on the Counterterrorism blog.

My proposal for the Society for Risk Analysis’s annual meeting in Boston has been accepted, in oral presentation format, for the afternoon of Wednesday, December 10th, 2008. Any Lifeboat members who will be in the area at the time are more than welcome to attend. Any suggestions for content would also be greatly appreciated; speaking time is limited to 15 minutes, with 5 minutes for questions. The abstract for the paper is as follows:

Global Risk: A Quantitative Analysis

The scope and possible impact of global, long-term risks presents a unique challenge to humankind. The analysis and mitigation of such risks is extremely important, as such risks have the potential to affect billions of people worldwide; however, little systematic analysis has been done to determine the best strategies for overall mitigation. Direct, case-by-case analysis can be combined with standard probability theory, particularly Laplace’s rule of succession, to calculate the probability of any given risk, the scope of the risk, and the effectiveness of potential mitigation efforts. This methodology can be applied both to well-known risks, such as global warming, nuclear war, and bio-terrorism, and lesser-known or unknown risks. Although well-known risks are shown to be a significant threat, analysis strongly suggests that avoiding the risks of technologies which have not yet been developed may pose an even greater challenge. Eventually, some type of further quantitative analysis will be necessary for effective apportionment of government resources, as traditional indicators of risk level- such as press coverage and human intuition- can be shown to be inaccurate, often by many orders of magnitude.

More details are available online at the Society for Risk Analysis’s website. James Blodgett will be presenting on the precautionary principle two days earlier (Monday, Dec. 8th).

Researchers have devised a rapid and efficient method for generating protein sentinels of the immune system, called monoclonal antibodies, which mark and neutralize foreign invaders.

For both ethical and practical reasons, monoclonals are usually made in mice. And that’s a problem, because the human immune system recognizes the mouse proteins as foreign and sometimes attacks them instead. The result can be an allergic reaction, and sometimes even death.

To get around that problem, researchers now “humanize” the antibodies, replacing some or all of mouse-derived pieces with human ones.

Wilson and Ahmed were interested in the immune response to vaccination. Conventional wisdom held that the B-cell response would be dominated by “memory” B cells. But as the study authors monitored individuals vaccinated against influenza, they found that a different population of B cells peaked about one week after vaccination, and then disappeared, before the memory cells kicked in. This population of cells, called antibody-secreting plasma cells (ASCs), is highly enriched for cells that target the vaccine, with vaccine-specific cells accounting for nearly 70 percent of all ASCs.

“That’s the trick,” said Wilson. “So instead of one cell in 1,000 binding to the vaccines, now it is seven in 10 cells.”

All of a sudden, the researchers had access to a highly enriched pool of antibody-secreting cells, something that is relatively easy to produce in mice, but hard to come by for human B cells.

To ramp up the production and cloning of these antibodies, the researchers added a second twist. Mouse monoclonal antibodies are traditionally produced in the lab from hybridomas, which are cell lines made by fusing the antibody-producing cell with a cancer cell. But human cells don’t respond well to this treatment. So Wilson and his colleagues isolated the ASC antibody genes and transferred them into an “immortalized” cell line. The result was the generation of more than 100 different monoclonals in less than a year, with each taking just a few weeks to produce.

In the event of an emerging flu pandemic, for instance, this approach could lead to faster production of human monoclonals to both diagnose and protect against the disease.

Journal Nature article: Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

Nature 453, 667–671 (29 May 2008) | doi:10.1038/nature06890; Received 16 October 2007; Accepted 4 March 2008; Published online 30 April 2008

Pre-existing neutralizing antibody provides the first line of defence against pathogens in general. For influenza virus, annual vaccinations are given to maintain protective levels of antibody against the currently circulating strains. Here we report that after booster vaccination there was a rapid and robust influenza-specific IgG+ antibody-secreting plasma cell (ASC) response that peaked at approximately day 7 and accounted for up to 6% of peripheral blood B cells. These ASCs could be distinguished from influenza-specific IgG+ memory B cells that peaked 14–21 days after vaccination and averaged 1% of all B cells. Importantly, as much as 80% of ASCs purified at the peak of the response were influenza specific. This ASC response was characterized by a highly restricted B-cell receptor (BCR) repertoire that in some donors was dominated by only a few B-cell clones. This pauci-clonal response, however, showed extensive intraclonal diversification from accumulated somatic mutations. We used the immunoglobulin variable regions isolated from sorted single ASCs to produce over 50 human monoclonal antibodies (mAbs) that bound to the three influenza vaccine strains with high affinity. This strategy demonstrates that we can generate multiple high-affinity mAbs from humans within a month after vaccination. The panel of influenza-virus-specific human mAbs allowed us to address the issue of original antigenic sin (OAS): the phenomenon where the induced antibody shows higher affinity to a previously encountered influenza virus strain compared with the virus strain present in the vaccine1. However, we found that most of the influenza-virus-specific mAbs showed the highest affinity for the current vaccine strain. Thus, OAS does not seem to be a common occurrence in normal, healthy adults receiving influenza vaccination.