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The objective for the body and more specifically cells is to monitor its energy potential and well being just like we’d monitor anything else with a modern information system/information technology (IS/IT).

Apoptosis is an intentional death of a cell that triggers a “natural” death, Necrosis is an unintentional death of a cell due to damage. While there are some inherent dangers with existing and making it as difficult today to avoid necrosis as it was yesterday, we can aim to scientifically identify apoptosis and manage it. Most of us are familiar with apoptosis, we call it cancer…a phenomenon where cells don’t know when to call it quits and we suffer as a result of the growth.

The specific technology doesn’t exist yet, but we require a mechanism to measure and regulate mitochondrion decisions on-demand. Let’s get to work people! Is there a way that we could constantly monitor mitochondrial regulation without losing blood regularly like a the annoying finger prick monitoring that diabetics have to currently endure.

Lance Becker does a good job of further elaborating on this topic and charging us with a new objective of creating the technologies that will assist in life management and extension.

Dear SCUN:

My scientific results force me to be worried.

I feel that I must repeat my kind request to you: Please, endorse judge Niemeier and his Cologne Court’s request for a scientific “safety conference” regarding CERN’s currently running nuclear collisions experiment.

For this experiment is based on outdated scientific knowledge from more than three years ago. The ignored new knowledge (derived from Einstein’s 1907 equivalence principle, Pauli’s quantum mechanics and Poincaré’s chaos theory) implies that the experiment has by now accumulated an approximately 1 percent probability of “earth evaporation” with a 2-cm left-over called a black hole forming in a few years’ time.

Worse: If CERN continues as planned for the next two months, the risk rises to 3 percent according to the best currently available knowledge (three times higher luminosity).

If “three percent” does not look like a large risk to you, imagine your child not returning from the boarding school to which you sent him with a probability of three percent. No parent would accept such a risk.

Therefore, dear Security Council: please, do allow for a public hearing of the un-disproved danger entailed by CERN’s refusal to double-check.

Take care,
Sincerely yours,
Otto E. Rossler, Father of Lampsacus and the Rossler attractor

CERN continues even though the matter is before the UN Security Council.

There is no counterproof to my published and public results. Presently the odds that the planet will be shrunk to 2 cm in perhaps 5 years’ time are 1:70, to be raised to 1:30 in the next two months if CERN continues.

Everyone who loves his child or his life or the planet by a higher factor is my ally. Please, request a response from your mayor and priest and counselor and merchant and newspaper office.

The best advisor in such an unprecedented situation may be your child since children still have a connection to heaven.

But hurry up. Maybe you are even a member of a social network?

Some people say that a calorie restriction (CR) diet is difficult to follow. It used to be. But things have changed: Thanks to great work by leading scientists, current approaches to calorie restriction are just as much about cell signaling as about limiting calories.

It is known, for example, that serious long-term CR dramatically lowers insulin levels.1 Another hormone, with a similar molecular structure, insulin-like growth factor one (IGF-I), shares the same pathway with insulin and is downregulated by CR in animal studies and by calorie restricted humans who do not follow high protein diets.2

And there’s the rub. For if you hope to benefit from calorie restriction and do not pay attention to the special properties of macronutrient intake, individual foods, and food preparation, you may get an unpleasant surprise: excessive stimulation of the insulin/IGF-I pathway. For example, in a study using healthy volunteers, just 50 grams of white potato starch sends glucose and insulin soaring3 to levels associated with increased risk of cancer, heart disease and diabetes.4

Back in the 1930s, when the term calorie restriction was first applied to Dr. Clive McCay’s rat and mouse experiments,5 it was entirely appropriate because the focus was on calories since he was looking at growth retardation. Of course, little was known about the signals involved in the life-extending effects of the diet. All that changed as scientists discovered important cell-signaling patterns that produce the phenomenal life-transforming effects.6

In 2008, The CR Way took the latest CR science and crafted it into a holistic lifestyle that makes following a CR diet easier by transforming it into a happy, positive lifestyle that focuses on living better now and quite possibly living longer. Recipes, food choices, and lifestyle are deliciously and strategically planned to reduce the insulin / IGF-I pathway activity – making disease risk plummet, while increasing the probability of a longer life.
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1. Fontana L, Meyer T.E., Klein S, Holloszy J.O. Long-Term Calorie Restriction Is Highly Effective In Reducing The Risk For Atherosclerosis In Humans. Proceedings of the National Academy of Science USA 2004;101(17):6659–6663.
2. Fontana L, Klein S, Holloszy J.O. Long-term low-protein low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. American Journal of Clinical Nutrition. 2006;84:1456–62.
3.Brand-Miller JC, et al. Mean changes in plasma glucose and insulin responses in 10 young adults after consumption of 50g carbohydrates from potato (high-glycemic index; GI) or barley (low-GI) meal. American Journal of Clinical Nutrition. 2005 Aug;82(2):350–4
4. Guideline for Management of Post-meal Glucose, International Diabetes Federation, 2007 ISBN 2−930229−48−9
5. McCay CM, Crowell MF, Maynard LA. Journal of Nutrition. l0:63–79, 1935
6. McGlothin PS, Averill MS. Advances in Calorie restriction. Antiaging Medicine. 2009 Aug;4(4):440–441

I got this tweet today, as a part of a larger conversation that technological breakthroughs could help predict disruptive economic times. During the past 10 days or so, the US and global financial markets have taken a deep plung, as a result of, well, according to the CIOs (chief investment officers) and politicians, we don’t know. The new industry pins the almost unanimous economic decisions of sell sell sell, to the latest new is geo-political interactions and/or financial specific news.

We see headlines like “Downgrade Ignites a Global Selloff” at the Wall Street Journal, referring to the Standard & Poor’s downgraded credit rating of US treasuries, which by the way soared during the selloff of equities, because of their relative strength.

More importantly than what to buy, none of the headlines, nor the vague analysis captures the actual root-cause of this regular, or rather, irregular economic downturn occurring over the past decade. The general ideal that one should be able to buy low and sell high that once held true in the 20th century no longer exists. The root of the problem is in our use of technologies to error-proof redundant problems in the modern work world. Further, we know that mostly all errors exist by the hands of humans. Thus, error-proofing can be synonymous with human-proofing. We usually think of technologies that replace human activity as a device or software…”the robots”, and those do exist, but they are less of a threat than the methodological technologies.

We rarely think of a routine as a technology, but they are. Benchmarking is a technology. With all of the methodological expertise being poured into corporations over the past 30 years, we’ve finally got somewhere, efficient. How many times have you heard that word at the office? Since the late 1960s and the creation of Poka Yoke by Dr. Shigeo Shingo, and on to Lean-Manufacturing, and Six-Sigma, and most recently the 3rd version of IT Infrastructure Library (ITILv3), we are actively depleting the work force to ensure our qualitative (effectiveness) and quantitative (efficiency) superiority to the competition.

Its a difficult dialogue to have, because a valid argument is: what’s wrong with business being efficient? My answer would be: Nothing at all. The problem comes into play when human-kind has rendered its ability to distribute value, obsolete. In the past we’ve distributed value through a currency of some sort, and that currency (in primitive times and modern day) is backed by more than gold or bonds, it is also backed by faith in a philosophical system that a woman/man get paid for an “honest days work”, quite the primitive slogan. In a knowledge economy where people aren’t performing back-breaking work at the volumes that they used to, and 10 knowledge workers of the 1980’s can be performed by 1 Project Manager using 30 years of benchmarked data with soft/hardware help, it’s difficult to spread the wealth that we once did.

When the markets sell off equities into cash, they are saying that the economy is inflated and weak. There are no buyers for the products being produced, because there are no jobs. There are no jobs, because of all of the error-proofing that proceeded them; and finally, it is exceedingly difficult to quantify what people’s knowledge, experience, existence is worth in the old paradigm. While it feels better to point the finger at the CEOs and Politicians today, of which I’d likely get a finger or two, the problem is that we are trying to distribute the wealth that still exists using an antiquated model.

If one looks at the M1&M2 numbers at the US Federal Reserve, they’ll notice that all of the money we need to fix/build anything still exists. This is the same across the globe. When the news says that money supply is lower, what they actually mean is that money distribution is lower, because the money supply, as the link shows is rarely diminished. As an economy retracts, funds return to its originator. The wealthiest of our species cannot justify how to spread a trillion dollars around, at the moment, because there fewer and fewer tasks to assign a wage and a human resource. I’ve got a few solutions to recommend in my next book project, Integrationalism: Essays on ownership and distributing value in the 21st century.

No other high-ranking personality on the planet is paying attention to the fact that a scientific proof of danger stays un-refuted for 3 years: That the planet will be shrunken to 2 cm (a black hole) in about 5 years’ time with a probability of 3 percent if the currently running grandiose LHC experiment is not halted immediately.

Since your mind is a unique bridge between the Eastern and the Western world view, you are the only institution on the planet which with authority can demand the necessary scientific safety conference. Even though this particular now and this particular existence is not everything, the sparing of suffering is a holy vocation.

Allow me to convey to you cordial greetings from your friend John S. Bell.

In deep respect

Sincerely yours,

Otto E. Rossler, chaos researcher