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Mixing neutrinos of colliding neutron stars changes how merger unfolds, simulations reveal

The collision and merger of two neutron stars—the incredibly dense remnants of collapsed stars—are some of the most energetic events in the universe, producing a variety of signals that can be observed on Earth.

New simulations of neutron star mergers by a team from Penn State and the University of Tennessee Knoxville reveal that the mixing and changing of tiny particles called that can travel astronomical distances undisturbed impacts how the merger unfolds, as well as the resulting emissions. The findings have implications for longstanding questions about the origins of metals and as well as understanding physics in , the researchers said.

The paper, published in the journal Physical Review Letters, is the first to simulate the transformation of neutrino “flavors” in neutron star mergers. Neutrinos are fundamental particles that interact weakly with other matter, and come in three flavors, named for the other particles they associate with: electron, muon and tau. Under specific conditions, including the inside of a neutron star, neutrinos can theoretically change flavors, which can change the types of particles with which they interact.

Impact of sleep duration on executive function and brain structure

Tai et al. examine sleep, cognitive and brain imaging data from middle-to-late life healthy individuals from the UK Biobank. They show that between six and eight hours of sleep duration is associated with the highest cognitive performance and larger grey matter volume in several areas of the brain.

The latest on nucleotide therapy development

Oligonucleotide therapies — engineered strands of DNA or RNA — are transforming modern medicine. These cutting-edge treatments bring a new level of precision in combating disease by targeting specific genes to be silenced, activated or edited. “Nucleotide therapeutics allow us to design predictable outcomes by modifying sequences to address almost any condition,” says Peter Guterstam, product manager at biotechnology company Cytiva.

Due to an influx of research in recent years, many nucleotide-based drug candidates, including genetic therapies and vaccines for cancer and viral infections, are now in advanced clinical trial stages. “The development timeline is much quicker than we are used to,” notes Guterstam.

Significant challenges arise during development of RNA and DNA based therapies. From mRNA vaccines to gene editing, scientists are refining delivery methods, optimizing synthesis, and tackling scaling hurdles.

GIST Research reveals a promising new target to thwart Alzheimer’s decades before symptoms start

A person will have Alzheimer’s years before ever knowing it. The disorienting erasure of memories, language, thoughts—in essence, all that makes up one’s unique sense of self—is the final act of this enigmatic disease that spends decades disrupting vital processes and dismantling the brain’s delicate structure.

Once symptoms surface and doctors make a diagnosis, though, it can often be too late. Damage is widespread, impossible to reverse. No cure exists.

Attempts to develop drugs that clear away toxic accumulations of amyloid-beta and tau proteins—hallmarks of the disease that cause neurons to die—have ended in hundreds of failed clinical trials. Today, some scientists are skeptical over whether removing amyloid plaques is even enough. Others have a hunch that the best line of attack won’t target just one aspect of the disease, but many of them, all at once.

Hit the wrong spot and an asteroid returns on a collision course

Asteroid deflection could save Earth, or accidentally doom it, depending on where we aim the impact.

Scientists caution that asteroid deflection must be precise, as striking the wrong spot risks sending it through a gravitational keyhole that sets up a future collision with Earth. Using lessons from NASA’s DART mission, researchers are developing probability maps to guide safer impact strategies.

Selecting the right spot to smash a spacecraft into the surface of a hazardous asteroid to deflect it must be done with great care, according to new research presented at the EPSC-DPS2025 Joint Meeting this week in Helsinki. Slamming into its surface indiscriminately runs the risk of knocking the asteroid through a ‘gravitational keyhole’ that sends it back around to hit Earth at a later date.

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