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Dec 12, 2023

Dr. Jamie Justice, Ph.D. — Executive Vice President, Health, XPRIZE Foundation

Posted by in category: life extension

XPRIZE Healthspan — A 7-year, $101 Million Global Competition To Revolutionize The Way We Approach Human Aging — Dr. Jamie Justice, Ph.D., — Executive Vice President, Health, XPRIZE Foundation.

Dec 12, 2023

Scientists Grew ‘Mini Brains’ From Stem Cells. Then, The Brains Sort-of Developed Eyes

Posted by in categories: biotech/medical, neuroscience

Mini brains grown in a lab from stem cells spontaneously developed rudimentary eye structures, scientists reported in a fascinating paper in 2021.

On tiny, human-derived brain organoids grown in dishes, two bilaterally symmetrical optic cups were seen to grow, mirroring the development of eye structures in human embryos.

This incredible result will help us to better understand the process of eye differentiation and development, as well as eye diseases.

Dec 12, 2023

Using solid-state nanopores and DNA barcoding to identify misfolded proteins in neurodegenerative disorders

Posted by in categories: biotech/medical, chemistry, nanotechnology, neuroscience

A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved in neurodegenerative disorders in blood samples. In their study, reported in the Journal of the American Chemical Society, the group used multiplexed DNA barcoding techniques to overcome problems with nanopore filtering techniques for isolating harmful oligomers.

Prior research has shown that the presence of harmful oligomers in the brain can lead to misfolding of proteins associated with neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. Medical researchers have been looking for a way to detect them in the blood as a way to diagnose neurodegenerative disease and to track the progression once it has been confirmed.

Unfortunately, finding them in complex mixtures such as blood has proven to be a daunting task. One approach has shown promise—using sensors—but to date, they cannot track target oligomers as they speed through customizable solid-state nanopore sensors. In this new effort, the research team overcame this problem by using customizable DNA nanostructures.

Dec 12, 2023

Epigenetics linked to the maximum life spans of mammals — including us

Posted by in categories: biotech/medical, chemistry, genetics

Some chemical tags on DNA, called epigenetic factors, that are present at a young age can affect the maximum life spans of mammal species.

Dec 12, 2023

‘Biocomputer’ combines lab-grown brain tissue with electronic hardware

Posted by in categories: biotech/medical, neuroscience

A system that integrates brain cells into a hybrid machine can carry out tasks such as voice recognition.

Dec 12, 2023

Unveiling the Tesla Cybertruck: A Revolutionary Vehicle from Tesla Executives

Posted by in categories: energy, engineering, sustainability, transportation

Sandy talks Cybertruck with 5 Tesla Execs! Lars Moravy: Head of Vehicle Engineering Franz von Holzhausen: Head of Design Drew Baglino: Head of Powertrain (battery + motors) and Energy Pete Bannon: Head of Low Voltage David Lau: Head of Software Munro Live is a YouTube channel that features Sandy Munro and other engineers from Munro & Associates.

Dec 12, 2023

LLM360: Towards Fully Transparent Open-Source LLMs

Posted by in category: futurism

Join the discussion on this paper page.

Dec 12, 2023

Is Consciousness First in Virtual Reality?

Posted by in categories: neuroscience, physics, virtual reality

The prevailing scientific paradigm is that matter is primary and everything, including consciousness can be derived from the laws governing matter. Although the scientific explanation of consciousness on these lines has not been realized, in this view it is only a matter of time before consciousness will be explained through neurobiological activity in the brain, and nothing else. There is an alternative view that holds that it is fundamentally impossible to explain how subjectivity can arise solely out of material processes-“the hard problem of consciousness”-and instead consciousness should be regarded in itself as a primary force in nature. This view attempts to derive, for example, the laws of physics from models of consciousness, instead of the other way around. While as scientists we can understand and have an intuition for the first paradigm, it is very difficult to understand what “consciousness is primary” might mean since it has no intuitive scientific grounding. Here we show that worlds experienced through virtual reality (VR) are such that consciousness is a first order phenomenon. We discuss the Interface Theory of Perception which claims that in physical reality perceptions are not veridical and that we do not see the “truth” but that perception is based on evolutionary payoffs. We show that this theory may provide an accurate description of perception and consciousness within VR, and we put forward an experimental study that could throw light on this. We conclude that VR does offer an experimental frame that provides intuition with respect to the idea that “consciousness is first” and what this might mean regarding the perceived world. However, we do not draw any conclusions about the veracity of this notion with respect to physical reality or question the emergence of consciousness from brain function.

Keywords: consciousness; interface theory of perception; perception; presence; real vs. virtual; virtual reality.

Copyright © 2022 Slater and Sanchez-Vives.

Dec 12, 2023

New space-saving RAM sticks that jam up to 128GB of memory in a laptop get industry’s stamp of approval — CAMM2 standard ratified by JEDEC

Posted by in categories: computing, space

SO-DIMM’s successor is official.

Dec 12, 2023

Phantom touch: Virtual reality can induce a mysterious tactile illusion, scientists find

Posted by in categories: neuroscience, virtual reality

In a new study published in Scientific Reports, researchers have uncovered a phenomenon known as the “phantom touch illusion,” where individuals experience tactile sensations without actual physical contact in a virtual reality (VR) setting. This intriguing discovery raises questions about how the brain processes sensory information.

Previous research has shown that our nervous system can differentiate between self-generated touch and touch from external sources, a process often described as tactile gating. This ability helps us understand our interactions with the world around us.

When you perform an action that results in self-touch, your brain anticipates this contact. It knows that the sensation is a result of your own movement. Because of this anticipation, the brain ‘turns down the volume’ on the sensory response. Essentially, it partially “cancels” or gates out the sensation because it’s expected and self-generated. This is why you can’t effectively tickle yourself – your brain knows the touch is coming and reduces the response.