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Feb 24, 2024

Next Generation Neural Interfaces: Research on Emerging Technologies at Imperial College London

Posted by in categories: biotech/medical, health, neuroscience

The era of bioelectronic healthcare is dawning upon us. As electronic systems shrink in size and improve in functionality, we see more and more emerging devices that can track vital signs, such as heart rate and blood pressure, realising the grand vision of highly connected sensor nodes monitoring patients’ health beyond the hospital doors. The real revolution in digital healthcare, however, lies in bringing not only the diagnostics but also the therapy to the patient which requires interfacing the world of electronics with biology.

Interfacing the nervous system provides an immense opportunity to observe (through recording) and modify (through stimulation) the functional state of the biological system to fundamentally understand various diseases and health conditions, and to ultimately develop suitable therapies through closed-loop systems [1]. Consequently, a host of neural interface modalities, with varying levels of invasiveness, have been developed over the past decades. Among all, interfacing at the individual neuron level allows the highest level of information transfer from the brain.

Despite the success of devices such as Cochlear Implants, interfacing at the individual neuron level is still severely limited due to challenges such as selectivity (for stimulation) and thermal-limitations imposed on data transmission to prevent neural tissue damage. The latter is a major bottleneck in improving information transfer rate of neural recording systems as they scale up. Hence, there is currently a tremendous drive to develop new enabling technologies for neuroscience to provide insightful views on how motor or sensory information is represented and transformed by the brain, as well as revealing how this complex system is affected by neurological injuries and disease.

Feb 24, 2024

(PDF) Universe as a partially computable information-processing system

Posted by in category: futurism

PDF | Universe as a partially computable information-processing system | Find, read and cite all the research you need on ResearchGate.

Feb 24, 2024

FRAUDULENT Scientific Study EPIDEMIC Destroying Credibility of Medical Research: Report

Posted by in categories: biotech/medical, electronics

Briahna Joy Gray and Robby Soave discuss a new report on credibility in academic papers. #science #research.

About Rising:
Rising is a weekday morning show with bipartisan hosts that breaks the mold of morning TV by taking viewers inside the halls of Washington power like never before. The show leans into the day’s political cycle with cutting edge analysis from DC insiders who can predict what is going to happen. It also sets the day’s political agenda by breaking exclusive news with a team of scoop-driven reporters and demanding answers during interviews with the country’s most important political newsmakers.

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Feb 24, 2024

Genetically engineered T cells for cancer immunotherapy

Posted by in categories: biotech/medical, chemistry, computing, genetics, nanotechnology

Relying on sub-wavelength nanostructures, metasurfaces have been shown as promising candidates for replacing conventional free-space optical components by arbitrarily manipulating the amplitude, phase, and polarization of optical wavefronts in certain applications1,2,3. In recent years, the scope of their applications has been expanded towards complete spatio-temporal control through the introduction of active metasurfaces. These developments open up exciting new possibilities for dynamic holography4, faster spatial light modulators5, and fast optical beam steering for LiDAR6. Large efforts have been channeled into various modulation mechanisms7. Microelectromechanical and nanoelectromechanical systems (MEMS and NEMS)8,9,10,11 have the advantages of low-cost and CMOS-compatibility, but the speed is limited up to MHz. Phase-change materials12,13,14 have fast, drastic, and non-volatile refractive index change, but lack continuous refractive index tuning and have a limited number of cycles constraining applicability to reconfigurable devices. Through molecule reorientation, liquid crystal can have index modulation over 10%, while under relatively low applied voltages Tunable liquid crystal metasurfaces, U.S. patent number 10,665,953 [Application Number 16/505,687]15. Techniques of liquid crystal integration have also advanced after decades of development. However, the tuning speeds are limited to kHz range16. Thermal-optic effects can induce relatively large refractive index changes17,18, but the speed is inherently limited and the on-chip thermal management can be challenging. The co-integration of transparent conductive oxide and metallic plasmonic structures5,6 has been demonstrated in epsilon-near-zero (ENZ) regime to control the wavefront of reflected light, but the low reflection amplitude induced by the optical loss of the materials and the ENZ regime is unavoidable.

In modern photonics, a multitude of technologies for tunable optics and frequency conversion19,20 are realized with nonlinear materials that have low loss and a strong χ effect, such as lithium niobate21,22, aluminum nitride23, and organic electro-optic (OEO) materials24. Their ultrafast responses make it possible to use RF or millimeter-wave control25. Developments in computational chemistry have also led to artificially engineered organic molecules that have record-high nonlinear coefficients with long-term and high-temperature stability26,27. However, their potential in modifying free-space light has been relatively unexplored until recently. Several OEO material-hybrid designs have demonstrated improved tunability of metasurfaces28,29,30. Utilizing dielectric resonant structures and RF-compatible coplanar waveguides, a free-space silicon-organic modulator has recently accomplished GHz modulation speed31. However, all demonstrations to date require high operating voltages ± 60V, due to low resonance tuning capability (frequency shift / voltage), which hinders their integration with electronic chips.

In this work, we propose combining high-Q metasurfaces based on slot-mode resonances with the unique nano-fabrication techniques enabled by OEO materials, which drastically reduces the operating voltage. The low voltage is mainly achieved from the ability to place the electrodes in close proximity to each other while hosting high-Q modes in between and the large overlap of the optical and RF fields in OEO materials. In the following sections, we first provide the design concepts and considerations for achieving a reduced operating voltage. Next, we numerically demonstrate the advantage of a particular selected mode compared to other supported modes in the structure. Finally, we experimentally realize our concepts and characterize the performance of the electro-optic metasurface.

Feb 24, 2024

Scientists Say The Universe Is In Someone’s Brain — And it’s Not Looking Good

Posted by in categories: robotics/AI, space

Read The Article Here https://time.com/6208174/maybe-the-universe-thinks/The concept that the Universe resembles a brain, a neural network, or a self-organizi…

Feb 24, 2024

New Color-Changing Invention Enables “Time Travel” Within Cells

Posted by in categories: biotech/medical, time travel

Researchers at Trinity College Dublin, working together with the Royal College of Surgeons in Ireland (RCSI), have developed special fluorescent, color-changing dyes that, for the first time, can be used to simultaneously visualize multiple distinct biological environments using only one singular dye.

When these dyes are encapsulated in delivery vessels, like those used in technologies like the COVID-19 vaccines, they “switch on” and give out light via a process called “aggregation-induced emission” (AIE). Soon after delivery into the cells their light “switches off” before “switching on” again once the cells shuttle the dyes into cellular lipid droplets.

Feb 24, 2024

Scientists are designing a supercollider so powerful it could push the boundaries of modern physics

Posted by in category: physics

CERN is designing the largest and most powerful supercollider of all time. It could solve some of the biggest mysteries of our universe.

Feb 24, 2024

MIT engineers test an idea for a new hovering rover

Posted by in categories: energy, space

Year 2021 face_with_colon_three


Because they lack an atmosphere, the moon and other airless bodies such as asteroids can build up an electric field through direct exposure to the sun and surrounding plasma. On the moon, this surface charge is strong enough to levitate dust more than 1 meter above the ground, much the way static electricity can cause a person’s hair to stand on end.

Engineers at NASA and elsewhere have recently proposed harnessing this natural surface charge to levitate a glider with wings made of Mylar, a material that naturally holds the same charge as surfaces on airless bodies. They reasoned that the similarly charged surfaces should repel each other, with a force that lofts the glider off the ground. But such a design would likely be limited to small asteroids, as larger planetary bodies would have a stronger, counteracting gravitational pull.

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Feb 24, 2024

MIT Scientists May Have Found a Cheap Way of Storing Huge Amounts of Energy in Cement

Posted by in categories: energy, sustainability, transportation

A team of MIT researchers has figured out a way to create a supercapacitor simply by mixing cement, the binding ingredient of concrete, and a fine charcoal product called carbon black together with water.

Better yet, this mixture could allow a home to store a full day’s worth of energy in its foundation, potentially paving the way to an efficient renewable energy storage solution that doesn’t rely on mining rare Earth metals.

Roads made up of the material could even power electric cars wirelessly, the researchers say, or windmills could store their generated energy in their base.

Feb 24, 2024

Innovation in Metalworking: Welding Metal Foam Without Melting Its Bubbles

Posted by in category: innovation

North Carolina State University researchers have discovered a new welding method for composite metal foam (CMF), preserving its light, strong, and thermally insulating properties, vital for numerous applications.

Researchers at North Carolina State University have now identified a welding technique that can be used to join composite metal foam (CMF) components together without impairing the properties that make CMF desirable. CMFs hold promise for a wide array of applications because the pockets of air they contain make them light, strong and effective at insulating against high temperatures.

Characteristics and Challenges of CMF.