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New research sheds light on what’s going on inside our heads as we decide whether to take a risk or play it safe. Scientists at Washington University School of Medicine in St. Louis located a region of the brain involved in decisions made under conditions of uncertainty, and identified some of the cells involved in the decision-making process.

The work, published July 27 in The Journal of Neuroscience, could lead to treatments for psychological and psychiatric disorders that involve misjudging risk, such as problem gambling and anxiety disorders.

“We know from human imaging studies that certain parts of the brain are more or less active in risk-seeking people, but the neural circuits involved are largely unknown,” said Ilya Monosov, PhD, an assistant professor of neuroscience and senior author on the study. “We found a population of value-coding neurons that are specifically suppressed when animals make a risky choice.”

We spend our lives surrounded by high-tech materials and chemicals that make our batteries, solar cells and mobile phones work. But developing new technologies requires time-consuming, expensive and even dangerous experiments.

Luckily we now have a secret weapon that allows us to save time, money and risk by avoiding some of these experiments: computers.

Dr. Demis Hassabis is the Co-Founder and CEO of DeepMind, the world’s leading General Artificial Intelligence (AI) company, which was acquired by Google in 2014 in their largest ever European acquisition. Demis will draw on his eclectic experiences as an AI researcher, neuroscientist and video games designer to discuss what is happening at the cutting edge of AI research, including the recent historic AlphaGo match, and its future potential impact on fields such as science and healthcare, and how developing AI may help us better understand the human mind.

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Studies are showing that anatomical patterning found in the brain’s cortex may be controlled by genetic factors.


The highly consistent anatomical patterning found in the brain’s cortex is controlled by genetic factors, reports a new study by an international research consortium led by Chi-Hua Chen of the University of California, San Diego, and Nicholas Schork of the J. Craig Venter Institute, published on July 26 in PLOS Genetics.

The human brain’s wrinkled cerebral cortex, which is responsible for consciousness, memory, language and thought, has a highly similar organizational pattern in all individuals. The similarity suggests that genetic factors may create this pattern, but currently the extent of the role of these factors is unknown. To determine whether a consistent and biologically meaningful pattern in the cortex could be identified, the scientists assessed brain images and genetic information from 2,364 unrelated individuals, brain images from 466 twin pairs, and transcriptome data from six postmortem brains.

They identified very consistent patterns, with close genetic relationships between different regions within the same brain lobe. The frontal lobe, which has the most complexity and has experienced the greatest expansion throughout the brain’s evolution, is the most genetically distinct from the other lobes. Their results also suggest potential functional relationships among different cortical brain regions.