Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 11367

This is actually pretty significant to see from DARPA; however, not a total shock given the importance of Synthetic Biology and various parties in the military understanding how CRISPR can be used as a weapon.

A new DARPA program could help unlock the potential of advanced gene editing technologies by developing a set of tools to address potential risks of this rapidly advancing field. The Safe Genes program envisions addressing key safety gaps by using those tools to restrict or reverse the propagation of engineered genetic constructs.

“Gene editing holds incredible promise to advance the biological sciences, but right now responsible actors are constrained by the number of unknowns and a lack of controls,” said Renee Wegrzyn, DARPA program manager. “DARPA wants to develop controls for gene editing and derivative technologies to support responsible research and defend against irresponsible actors who might intentionally or accidentally release modified organisms.”

Safe Genes was inspired in part by recent advances in the field of “gene drives,” which can alter the genetic character of a population of organisms by ensuring that certain edited genetic traits are passed down to almost every individual in subsequent generations. Scientists have studied self-perpetuating gene drives for decades, but the 2012 development of the genetic tool CRISPR-Cas9, which facilitates extremely precise genetic edits, radically increased the potential value of—and in some quarters the demand for—experimental gene drives.

Continue reading “Setting a Safe Course for Gene Editing Research” | >

Advancing efforts around Synthetic Bio into the semiconductor space.

“We hope that ongoing advances in our method may lead to the development of new organic electronic devices, including semiconductor and luminescent materials,” say Segawa and Itam.

Thiophene-fused polycyclic aromatic hydrocarbons (PAHs) are known to be useful as organic semiconductors due to their high charge transport properties. Scientists have developed a short route to form various thiophene-fused PAHs by simply heating mono-functionalized PAHs with sulfur. This new method is expected to contribute towards the efficient development of novel thiophene-based electronic materials.

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Physicists have for the first time succeeded in directly visualising on small scales how a material abruptly changes its state from conducting to insulating at low temperatures. Researchers Erik van Heumen of the University of Amsterdam and Alex McLeod from the University of California thereby provide evidence for a 60-year-old theory that explains this phenomenon and pave the way for more energy efficient technologies. The team’s experiments are described in the latest edition of Nature Physics.

Materials that conduct electricity at high temperature but are insulating at lower temperatures have been known for decades. However, until recently it was not possible to directly measure how such phase transitions proceed on small length scales. Using a new technique, Van Heumen and McLeod are now able to visualise the changes taking place in the material during such a phase transition on the nanometer scale.

In their experiments, the team observed a so-called percolation transition taking place among the electrons in the material. Above a certain critical temperature, the electrons can move relatively easily through the material enabling the flow of electrical current. When the temperature drops below a threshold temperature, small imperfections in the material trigger a kind of traffic jam for the electrons. Starting from small nanometer length scales, this traffic jam slowly grows outwards across the entire material. The previously freely moving electrons come to an abrupt halt and the material loses its conducting properties.

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